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  • Covaxin Publications2

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    This document lists 8 publications related to BBV152, an inactivated SARS-CoV-2 vaccine. The publications include results from Phase 1 and Phase 2 human clinical trials demonstrating the safety and immunogenicity of the vaccine. Additional publications show the vaccine effectively neutralizes variants of concern like B.1.1.7, B.1.617, and B.1.1.28 in human and animal studies. Preclinical studies in hamsters and non-human primates found the vaccine to be immunogenic and provide protective efficacy.

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    bharatbiotech

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    This document lists 8 publications related to BBV152, an inactivated SARS-CoV-2 vaccine. The publications include results from Phase 1 and Phase 2 human clinical trials demonstrating the safety and immunogenicity of the vaccine. Additional publications show the vaccine effectively neutralizes variants of concern like B.1.1.7, B.1.617, and B.1.1.28 in human and animal studies. Preclinical studies in hamsters and non-human primates found the vaccine to be immunogenic and provide protective efficacy.

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    © All Rights Reserved
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    8 views1 page

    Covaxin Publications2

    Uploaded by

    Pavani
    This document lists 8 publications related to BBV152, an inactivated SARS-CoV-2 vaccine. The publications include results from Phase 1 and Phase 2 human clinical trials demonstrating the safety and immunogenicity of the vaccine. Additional publications show the vaccine effectively neutralizes variants of concern like B.1.1.7, B.1.617, and B.1.1.28 in human and animal studies. Preclinical studies in hamsters and non-human primates found the vaccine to be immunogenic and provide protective efficacy.

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    of 1

    PUBLICATIONS

    Sr. No Published Title Journal


    1. Phase 2 Human Clinical Trial Safety and immunogenicity clinical
    trial of an inactivated SARS-CoV-2
    https://doi.org/10.1016/S14 vaccine, BBV152 (a phase 2,
    73-3099(20)30942-7 double-blind, randomised
    controlled trial) and the
    persistence of immune responses
    from a phase 1 follow-up report
    2. Phase 1 Human Clinical Trial Safety and immunogenicity of an
    inactivated SARS-CoV-2 vaccine,
    https://doi.org/10.1016/S14 BBV152: a double-blind,
    73-3099(21)00070-0 randomised, phase 1 trial
    3. Neutralization of UK Variant Inactivated COVID-19 vaccine
    (B.1.1.7) BBV152/COVAXIN effectively
    neutralizes recently emerged
    https://doi.org/10.1093/jtm B.1.1.7 variant of SARS-CoV-2
    /taab051
    4. Neutralization of Double Neutralization of variant under
    mutant (B.1.617) investigation B.1.617 with sera of
    BBV152 vaccinees
    https://doi.org/10.1093/cid
    /ciab411
    5. Neutralization of Brazil Neutralization of B.1.1.28 P2 variant
    variant of concern P2 with sera of natural SARS-CoV-2
    (B.1.1.28) infection and recipients of BBV152
    vaccine
    https://doi.org/10.1093/jtm
    /taab077
    6. Hamster Efficacy Study Immunogenicity and protective
    efficacy of BBV152, whole virion
    https://doi.org/10.1016/j.isci inactivated SARS- CoV-2 vaccine
    .2021BBV152-UK .102054 candidates in the Syrian hamster
    model
    7. Non-Human Primate Immunogenicity and protective
    Efficacy Study efficacy of inactivated SARS-CoV-2
    vaccine candidate, BBV152 in
    https://doi.org/10.1038/s41 rhesus macaques
    467-021-21639-w
    8. Preclinical Safety and Th1 Skewed immune response of
    Immunogenicity Whole Virion Inactivated SARS-
    CoV-2 Vaccine and its safety
    https://doi.org/10.1016/j.isc evaluation
    i.2021.102298

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