Questions

) November 25, 2018 ! 0 * 3637

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Q.) Risk factors that

predispose to leukemia
include all EXCEPT

Infectious mononucleosis

Ionizing radiation

Down syndrome

Myelodysplastic syndrome

Q.) The following

statement is TRUE in
acute lymphoblastic
leukemia
 Splenomegaly is less common
than hepatomegaly

It is more common in adult

Testicular involvement is
common

It may progress to mycosis

fungoides

Q.) Confirmation of
myelofibrosis is usually
done by

Immunophenotyping

Bone marrow biopsy

Splenic aspiration

Bone marrow aspiration

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Q.) The following is NOT

a feature of blast cells
observed in leukemias

Thin rim to moderate amount

of cytoplasm

Nucleus with open chromatin

and 1 to 5 nucleoli

High N:C ratio

Large pleomorphic nuclei

Q.) In ALL, the

prognosis is unfavorable

When the total WBC count is

low
 When the age of the patient is
between 2 to 10 years

In a female child

When Philadelphia
chromosome is present

Q.) The syndrome which

has an increased
predisposition for
leukemia is

Down syndrome

Klinefelter syndrome

Peutz Jeghers syndrome

Turner syndrome

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Q.) The monoclonal

antibodies which show
positivity in AML is

CD2 and CD3

CD13 and CD33

CD5 and CD7

CD10, CD19 and CD22

Q.) The cells associated

with formation of
chloroma are

Plasmablasts
 Lymphoblasts

Myeloblasts

Immunoblasts

Q.) Myelodysplastic
syndrome has following
characteristics EXCEPT

There is a risk of development

of AML

It is a congenital stem cell

disorder

It is characterized by dysplasia
in non-lymphoid lineage

It shows megaloblastoid and

ineffective hematopoiesis

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Q.) The Cytochemical
stain which
distinguishes
Myeloblast from
Lymphoblast is

TRAP

Myeloperoxidase

Myeloesterase

Leukocyte Alkaline
Phosphatase

Q.) The cytochemical

stain which shows block
positivity in
 lymphoblast is

Sudan black

PAS

Nonspecific esterase

Myeloperoxidase

Q.) The following is NOT

a common presenting
feature observed in AML

Hepatosplenomegaly frequent

Leukostasis common

Predominantly seen in adults

Leukemic meningitis common

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Q.) Following
biochemical feature is
NOT seen in tumor lysis
syndrome

Hyperuricosuria

Hyperkalemia

Hyperuricemia

Hypercalcemia

Q.) According to WHO,

the minimum
percentage of myeloid
blasts in bone marrow
necessary for the
 diagnosis of AML is

20%

40%

10%

30%

Q.) The following

disorder shows pawn
ball megakaryocytes

Pernicious anemia

Hodgkin lymphoma

Immune thrombocytopenic
purpura

Myelodysplastic syndrome

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Q.) Auer rods are found
in the cytoplasm of

Lymphoblast

Monoblasts

Myeloblast

Megaloblast

Q.) Both pre-B and pre-

T lymphoblasts are
positive for

Alkaline phosphatase
 Terminal deoxynucleotidyl-
transferase

CD19 and CD10

CD5 and CD8

Q.) The monoclonal

antibodies which show
positivity in B-lineage
ALL is

CD13 and CD33

CD2 and CD3

CD10, CD19 and CD22

CD5 and CD7

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Q.) Auer rods represent

Ribosomes

Azurophilic granules

Mitochondria

Secondary granules

Q.) The morphological

type of leukemia which
may show Auer rods is

Chronic myeloid leukemia

 Acute Myeloid Leukemia

Acute lymphoblastic leukemia

Chronic lymphoid leukemia

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DRISHTI SHARMA
Hey, This is Drishti Sharma,
graduated with BSc. from
IGNOU and have completed
a Diploma in Medical
Laboratory Technology. I
love to write and share my words with the world.
I also engage myself in teaching which enhances
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ACUTE LEUKEMIA ACUTE LEUKEMIA QUIZ

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