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CONCEPTUAL FRAMEWORK

Input Process Output

Based on gathered data from A series of standard viral • This research defines device
newspapers and interviews culture tests validated for that can automatically sense,
among the persons who routine use in the clinical process sensory information,
experienced of getting laboratory, as well as the and perform actions that
screened for COVID-19 with CDC (Centers for Disease benefit people who infected
a nasal swab test, they Control) Automation of and with disabilities.
described it as painful and Nasopharyngeal swab test
unpleasant from others. A will be used to establish a • This form of technology can
COVID-19 test is performed collection of well- be used on a much higher
by inserting a 6 inches long characterized specimens. scale with a greater number
swab into the nose all the way of uses
to the nasal cavity, where it is One aliquot will be tested in
rotated several times for 15 real-time using the requisite • We have an opportunity to
seconds. Then, repeated in viral culture reference expand the usage of assistive
the other nostril to ensure methods, one aliquot will be robotics to help and develop
enough material is collected. used for any Respiratory the country to combat
These tests are currently related disease, reference COVID-19 (Corona Virus
carried out by medical testing, one aliquot will be Disease)
professionals. The researchers used to extract nucleic acid in
present this Robotic real-time, and one aliquot of
Technology, which aids the UTM (Universal
frontline workers in Transport Medium for
minimizing manual testing viruses) will be archived for
and reducing the risk of viral sequencing to confirm
infection while also reducing Influenza-positive specimens.
the requirement for skilled
nurses and doctors. This is
due to the robot's efficiency
and lack of fatigue. This
method has the potential to
cut the time and effort
required for Covid-19 testing
by tenfold, allowing for the
diagnosis of a variety of
respiratory disorders. Each
year the morbidity and
mortality associated with
respiratory tract infections
fluctuate seasonally. This rise
and fall are associated with
the changing prevalence of
respiratory viruses in every
population.

LISTS OF RECOMMENDED CLINICAL SPECIMENS TO COLLECT FROM


OUTPATIENTS, INPATIENTS, AND FATAL CASES IN THE SETTING OF AN
UNEXPLAINED RESPIRATORY DISEASE
The specimens are listed in order of priority; those listed first are those most useful for testing for
the greatest number of different pathogens with a single clinical specimen.

OUTPATIENT INPATIENT FATAL CASES


Upper Respiratory Lower Respiratory All available premortem
• Nasopharyngeal (NP) • Bronchoalveolar lavage, specimens
and oropharyngeal (OP) tracheal aspirate, pleural fluid
• Nasopharyngeal • Sputum Tissue
wash/aspirate • Fixed tissue from all
Upper Respiratory major organs (e.g., lung,
Lower Respiratory • Nasopharyngeal (NP) and heart, spleen, liver,
• Sputum oropharyngeal (OP) swabs brain, kidney, adrenals)
• Nasopharyngeal • Non-fixed tissue from
Blood wash/aspirate lung and upper airways
• Serum: Acute (at (e.g., trachea, bronchus)
onset) and Blood
convalescent (3-6 • Serum: Acute (at onset) and Lower Respiratory
weeks post onset) convalescent (3-6 weeks post • Bronchoalveolar
• Blood (plasma) onset) lavage, tracheal aspirate,
• Whole blood (plasma) pleural fluid
Urine Tissue (e.g., lung) • Sputum

Stool Urine Blood


• Serum
Stool • Blood (plasma)

Deep lung swab for bacterial


culture

REFERENCES
https://clinicaltrials.gov/ct2/show/NCT01083511
https://www.cdc.gov/urdo/downloads/speccollectionguidelines.pdf

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