1.Company officials were concerned about the length of time a particular drug product retained its
potency. A random sample of 10 bottles of the product was drawn from the production line and
analyzed for potency. A second sample of 10 bottles was obtained and stored in a regulated
environment for a period of 1 year. The readings obtained from each sample are given:

Fresh Stored
10.2 10.6 9.9 9.7
10.5 10.7 9.6 9.5
10.3 10.2 11.1 9.6
10.9 10.0 10.2 9.8
9.8 10.6 10.1 9.9
Test if the potency of the drug changes after a year. Use 𝛼 = 0.05.

1. State the hypothesis 

Ho=µF=µS
Ha=µF≠µS
(Two-tailed test)

2.Specification of the level of significance

α=0.05

3.Test Statistics
n1=10 S1=1.04
n2=10 S2=1.89
k=2
n1+n2-2 > or ≤ 30
n=20
10+10-2 > or ≤ 30
18≤30 max ( S12 , S22 )
>¿ ≤ F α , ( V ,V 2)
t-test for 2 min ( S 12 , S 22 ) 1

independent samples
1.89
>¿ ≤ F 0.05 , ( k−1, n−2)
1.04
1.81>¿ ≤ F 0.05 , ( 2−1, 20−2)

1.81>¿ ≤ F 0.05 , ( 1 ,18)

4.Determine the critical value/s. 

Zα
, (n1+n2−2 )(two-tailed test)
2
Z 0.05
, ( 10+10−2)
2
Z 0.025, 18=2.101
5.Compute the test value. 
n1 =10 s12=1.04 x́1=¿10.38 x́1 −x́2
2
|t c|=
n2 =10 s =1.89 x́ 2=9.94 ( n1−1 ) S12 + ( n 2−1 ) S 22 1 1
2

√( n 1+ n2−2 )( )
n1 n2
+

10.38−9.94
|t c|=
(√ ( 10−1) 1.04+ ( 10−1 ) 1.89 1 1
10+10−2 )( 10 + 10 )
|t c|=¿0.29

6.Make a decision and conclusion

0.29<2.101

Decision: Fails to reject Ho

Conclusion: The evidence is not sufficient to reject the claim