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Evidence for this early The active agent

use of willow as an within willow bark


analgesic and was salicin, which
antipyretic first would later form the
surfaced in 1862. Edwin basis of the discovery
Smith (1822–1906) of aspirin

Weeping willow
Oxford scientists, John to salicylic acid
Poole and John French,
In 1876, the first
postulated that
clinical trial of
inhibiting platelet
salicin was
function might be key
published by
to treating pathological
Thomas Maclagan
thrombus formation
(1838–1903)

The effect of
The aspirin story –
aspirin on Early
platelets from willow to evidence for
wonder drug salicin
ADRIANA
GONZALEZ
ESPARZA 3MA

A new technique,
light transmission He investigated the
aggregometry effects of salicylate in
provided a tool to relieving the
investigate aspirin’s symptoms of
rheumatic fever
effects on platelets Three key
figures in the
discovery of
aspirin

They acetylated a Arthur Eichengrun


phenolic group Felix Hoffmann
from salicylic acid,
producing And Heinrich Dreser
acetylsalicylic acid.

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