Drug Mechanism of action Indication / Adverse effect Nursing Responsibilities

name Contraindica
tion
Generic Aspirin is known as a Indication: Body as a Before
name: salicylate and a Aspirin in Whole: Hypersensi Dx.
Aspirin nonsteroidal anti- CKD patients tivity
Brand inflammatory drug to decrease (urticaria, bronchos  Lab tests:
name: (NSAID). It works by cardiovascula pasm, anaphylactic frequent PT and
ZORprin blocking a certain r risk and to shock (laryngeal INR with
Classificati natural substance in slow renal edema). CNS: Dizz concurrent
on: your body to reduce disease iness, confusion, anticoagulant
CENTRAL pain and swelling. progression. drowsiness. Speci therapy; more
NERVOUS al frequent fasting
SYSTEM http:// Contraindica Senses: Tinnitus, blood glucose
AGENT; www.robholland.com tion: hearing levels with
ANALGESI › data History of loss. GI: Nausea, diabetes.
C, Web results hypersensitiv  Assessed for
SALICYLAT CYCLOSPORINE - ity to the allergy
E; RobHolland.com salicylates
history of the
ANTIPYRET including
IC; methyl patient.
ANTIPLATE salicylate (oil  Obtained vital
LET of sign
Route: wintergreen);
P.O sensitivity to Tx.
Dosage: other NSAIDs;  Performed a
350–650 patients with thorough
mg "aspirin physical
triad" (aspirin assessment as a
sensitivity, baseline data
nasal polyps, before
asthma); administering
drug.
Drug to drug  Assisted patient
interactions : in taking
Aminosalicyli medication
c acid  Prepared the
increases risk right medication
of and the dosage
SALICYLATE Edx.
toxicity.
Ammonium  Instructed
chloride and patient to avoid
other alcohol when
ACIDIFYING taking large
AGENTS doses of aspirin.
decrease  Encouraged
renal patient to
elimination consult physician
and increase before using
risk of aspirin for any
SALICYLATE fever
toxicity. accompanied by
rash, severe
headache, stiff
neck, marked
irritability, or
confusion (all
possible
symptoms of
meningitis).
 Instructed
patient to
observe and
report signs of
bleeding (e.g.,
petechiae,
ecchymoses,
bleeding gums,
bloody or black
stools, cloudy or
bloody urine).

During

Dx.

 Assessed pain
and/or pyrexia
one hour
before or after
medication.
 Assessed other
medication for
possible
interactions –
especially
warfarin which
is a special
hazard
 Assessed
patient for
 signs of
bleeding
(petechiae,
ecchymosis,
bloody or black
stools, bleeding
gums).

Tx.

 Discontinued
drug if there is a
rebound effect.
 Provided a glass
of water.
 Provided safety
measures.
(proper
positioning,
breathing
pattern, and
identifying
hazardous
area).

Edx.

 Instructed
patient to drink
adequate fluids
while taking
aspirin
 Informed the
client that it
may
experience
these side
effects:
Nausea, GI
upset,
heartburn (take
drug with
 food); easy
bruising, gum
bleeding
(related to
aspirin’s effects
on blood
clotting).
 Advised patient
not cut, crush,
or chew
sustained-
release
products.

After:

Dx.

 Implemented
appropriate
manual
therapy
techniques,
physical
agents, and
therapeutic
exercises to
reduce pain
and decrease
the need for
aspirin and
other NSAIDs.
 Assessed pain
and other
variables
(range of
motion, muscle
strength) to
document
whether this
drug is
successful in
 helping
manage the
patient’s pain
and decreasing
impairments.
 Assessed blood
pressure
periodically
and compare
to normal
values (See
Appendix F).
Aspirin and
other NSAIDs
can increase
blood pressure
(BP) in certain
patients.

Tx.

 Be alert for
signs of GI
bleeding,
including
abdominal
pain, vomiting
blood, blood in
stools, or black,
tarry stools.
Report these
signs to the
physician
immediately.
 Provided
safety
measures.
(established
rapport,
 voiding patient
before
medication,
supporting
psychological
and physical
health
 Assisted
patient to
explore other
nonpharmacol
ogic methods
to reduce
chronic pain,
such as
relaxation
techniques,
exercise,
counseling, and
so forth.

Edx.

 Instructed
patient to
report ringing
in the ears;
dizziness,
confusion;
abdominal
pain; rapid or
difficult
breathing;
nausea,
vomiting,
bloody stools.
 Advised patient
to take extra
precautions to
keep this drug
out of the
reach of
 children; this
drug can be
very dangerous
for children.
 Instructed
patient to use
the drug only
as suggested;
avoid
overdose.
Avoid the use
of other over-
the-counter
drugs while
taking this
drug. Many of
these drugs
contain aspirin,
and serious
overdose can
occur.

Drug name Mechanism of action Indication/ Adverse Nursing

Contraindicatio effect responsibilities
n
Generic name: Intensifies activity of Indication: CNS: Before
Medazolam gamma-aminobenzoic Midazolam is Retrograde Dx.
Brand name: acid (GABA), a major used before amnesia,  Assessed for
Versed inhibitory surgery or a headache, the allergy
Classification: neurotransmitter of the procedure. It euphoria, history of
CENTRAL brain, by interfering with helps to cause drowsiness, patient to
NERVOUS its reuptake and drowsiness, excessive the drugs
SYSTEM promoting its decrease sedation,  Monitored
AGENT; accumulation at neuronal anxiety, and to confusion. vital signs.
BENZODIAZEPI synapses. This calms the decrease your CV:  Ensured
NE ANXIOLYTIC; patient, relaxes skeletal memory of the Hypotensio absence of
SEDATIVE- muscles, and in high surgery or n. Special any
HYPNOTIC doses produces sleep. procedure. This Senses: complication
Route: medication may Blurred s.
IM http:// also be used to vision,
Dose: www.robholland.com › help with diplopia, Tx.
0.08mg data anesthesia or to nystagmus,  Performed a
Web results sedate people pinpoint thorough
MIDAZOLAM who need a pupils. GI: physical
HYDROCHLORIDE - tube or Nausea, assessment
RobHolland.com machine to help vomiting. as a baseline
with breathing. Respiratory: data before
Contraindicatio Coughing, administerin
n: laryngospas g drug.
Intolerance to m (rare),  Ensured that
benzodiazepine respiratory prescribed
s; acute arrest. Skin: dose is
narrow-angle Hives, administered
glaucoma; swelling, .
shock, coma; burning,  Provided
acute alcohol pain, comfort
intoxication; induration measures.
intra-arterial at injection (privacy, and
injection. site, anxiety)
tachypnea.
Drug to drug Body as a Edx.
interactions: Whole:  Advised
Cimetidine Hiccups, patient that
increases chills, he/she may
diazepam weakness. experience
plasma levels, some loss of
increases memory
toxicity; may following
decrease administrati
antiparkinson on.
effects of  Instructed
levodopa; patient with
proper
positioning.
 Encouraged
patient to
avoid the
use of
grapefruit
 products for
a short time
after taking
midazolam.
May interact
with
midazolam
and lead to
potentially
dangerous
effects

During
Dx.
 Assessed
patient of
breathing
techniques
 Assessed
patient for
compliance
to the
medication
to be given.
 Observed for
any
abnormal
swelling,
clotting, and
pain.
Tx.
 Noted
psychic and
physical
dependence
may occur in
patients on
long-term
high dosage
therapy, in
those with
histories of
alcohol or
drug
addiction, or
in those who
self-
medicate.
  Assisted
patient
ambulation
 Ensured
patients
level of
mental
status.

Edx.
 Instructed
patient to
report any
signs of
itching,
swelling in
the ankles,
sore throat,
easy
bruising.
 Encouraged
patients to
notify their
nurse if they
have trouble
breathing or
notice any
swelling.
 Advised
significant
others to
report if
symptoms
persist.

After
Dx.
 Monitored
and record
patient
response to
medication
and level of
sedation.
 Inspected
insertion site
for redness,
 pain,
swelling, and
other signs
of
extravasatio
n during IV
infusion.
 Monitor for
hypotension,
especially if
the patient is
premediated
with a
narcotic
agonist
analgesic
Tx.
 Performed
cardio
respiratory
monitoring
 Provided
safety
measures.
(proper
positioning,
breathing
pattern, and
identifying
hazardous
area).
 Performed
continue
physical
assessment
as baseline
data to the
medication
given.

Edx.
 Instructed
patient not
drive or
engage in
potentially
hazardous
 activities
until
response to
drug is
known. You
may feel
drowsy,
weak, or
tired for 1–2
d after drug
has been
given.
 Instructed
patient to
avoid alcohol
intake.
 Advised to
report with
physician
before
taking any
OTC drugs.