Tabaco National High School

Tabaco City
rd
3 Summative Exam in General Biology 1
2nd Semester, S.Y. 2020-2021

NAME: _____________________________________________________ Grade level: 11 (STEM) block: _______ Date: _______________

I. Multiple Choice. Read the following items carefully and choose the correct answer from the choices for each
item. Write the CAPITAL letter of your choice on the space provided below.

_______ 1. Which of the following is true to chromatid? 

A. a replicate chromosome  B. a chromosome found outside the nucleus 
C. a chromosome in G1 of the cell cycle D. a special region that holds two centromeres together
_______ 2. In which phase of mitosis do centrioles begin to move apart in cells?
A. prophase B. prometaphase C. metaphase D. telophase
_______ 3.  Which term describes two centrosomes arranged at opposite poles of the cell? 
A. telophase B. anaphase  C. prometaphase D. prophase
________4. A cell holding 88 chromatids at metaphase of mitosis would, at its completion, produce two nuclei
each containing how many chromosomes? 
A. 12 B. 22 C. 44 D. 88
_______ 5. During which phase of cell cycle does DNA replication occur?
A. G0 B. G2 C. G1 D. S
_______6. Suppose you are looking through a microscope at a squashed onion root tip. The chromosomes of
many of the cells are observable. In some cells, replicated chromosomes are aligned along the center or
equatorial plate of the cell. These cells are in which stage of mitosis? 
A. telophase B. prophase C. anaphase D. metaphase
_______7. During which phases of mitosis are chromosomes composed of two chromatids? 
A. from interphase through anaphase B. from G1 of interphase through metaphase 
C. from metaphase through telophase D. from G2 of interphase through metaphase
_______8. Which term describes centromeres uncoupling, sister chromatids separating, and the two new
chromosomes moving to opposite poles of the cell? 
A. telophase B. anaphase C. prophase D. metaphase
_______9. Which of the following is one difference between higher plants and animals regarding mitosis and
cytokinesis? 
A. In plants, sister chromatids are identical, but they differ from one another in animals. 
B. A cell plate in plants begins to form at telophase, whereas in animals a cleavage furrow is initiated at
that stage 
C. the spindles in plants contain microfibrils in addition to microtubules, whereas animal spindles don 
not contain microfibrils.
D. Plant chromosomes become attached to the spindle at prophase, whereas in animals, chromosomes
do not become attached until anaphase.
_______ 10.  Which of the following happens at the end of meiosis I? 
A. Homologous chromosomes are separated. B. The chromosome number per cell is conserved. 
C. Sister chromatids are separated. D. Four daughter cells are formed.
_______ 11. Which of the following characterizes prophase 1 of meiosis from prophase of mitosis?
A. chromosomes become visible B. spindle forms
B. homologous chromosomes pair up D. nuclear membrane breaks down
_______ 12. You have in your possession a microscope slide with meiotic cells on it and a light microscope. What
would you look for if you wanted to identify metaphase I cells on the slide? 
A. A visible nuclear envelope B. Separated sister chromatids at each pole of the cell 
C. Tetrads lined up at the center of the cell D. A cleavage furrow
_______ 13.   If there are 24 chromatids in a cell at metaphase, how many chromosomes are there in each
daughter cell following cytokinesis?
     A) 12 B) 24       C) 48 D) 40
_______ 14. Homologous chromosomes synapse and crossing over occurs. 
A. The statement is true for mitosis only. B. The statement is true for meiosis I only. 
C. The statement is true for meiosis II only. D. The statement is true for mitosis and meiosis I.

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_______ 15. How do the daughter cells at the end of mitosis and cytokinesis compare with their parent cell when
it was in G1 of the cell cycle? 
A. The daughter cells have half the amount of cytoplasm and half the amount of DNA. 
B. The daughter cells have half the number of chromosomes and half the amount of DNA. 
C. The daughter cells have the same number of chromosomes and half the amount of DNA. 
D. The daughter cells have the same number of chromosomes and the same amount of DNA
_______ 16. Which of the following are primarily responsible for cytokinesis in animal cells?
A. kinetochores B. centrioles C. Golgi-derived vesicles D. actin filaments
_______ 17. If the cell whose nuclear material is shown in Figure 1 continues toward completion of mitosis, which
of the following events would occur next?
A. cell membrane synthesis
B. spindle fiber formation 
C. nuclear envelope breakdown 
D. formation of telophase nucleoli
_______ 18. Nerve and muscle cells are in this phase: 
A. G0 B. G1 C. S D. G2.
_______ 19. Where do the microtubules of the spindle originate during mitosis in both plant and animal cells?
A. centromere   B. chromatid   C. centriole  D. centrosome
_______ 20.  Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an
abnormal total number of chromosomes. Why might this occur?
A. Cancer cells are no longer density dependent.
B. Cancer cells are no longer anchorage dependent.
C. Chromosomally abnormal cells can still go through cell cycle checkpoints.
D. Chromosomally abnormal cells still have normal metabolism

II. Label the parts of the following pictures and answer the given questions for each item.

3. _____________________________
____________________ 1.

4.
_____________________________

2. What stage? 5. What stage?

______________________________ _____________________________

6. mitosis/meiosis?
________________________________

8.
________________________

7. mitosis/meiosis?
_____________________________
9. What stage? 10. What stage?
________________________________ _________________________________

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 Tabaco National High School
Tabaco City
rd
3 Summative Exam in General Biology 1
2nd Semester, S.Y. 2020-2021

NAME: _____________________________________________________ Grade level: 11 (STEM) block: _______ Date: _______________

I. Multiple Choice. Read the following items carefully and choose the correct answer from the choices for each
item. Write the CAPITAL letter of your choice on the space provided below.

_______ 1. Which of the following characterized Down’s Syndrome?

A. 19 trisomy B. 21 trisomy C. only one X chromosome D. two X and one Y
_______ 2. Which syndrome occurs when individual somatic cell contains three sex chromosome XXX?
A. Down’s Syndrome B. Super female B. Klinefelter’s Syndrome D. Turner’s Syndrome
_______ 4. One possible result of chromosomal breakage is for a fragment to join a non-homologous
chromosome. What is this alteration called?
A. Deletion B. Disjunction
C. Inversion D. Translocation
_______ 5. Which of the following is true to figure 1?
A. Normal male
B. Normal female
C. Male with Monosomy X
D. Female with Turner’s Syndrome
_______ 6. Which of the following best describes a karyotype? Figure 1
A. A display of every pair of homologous chromosome within a cell, organized according to size
and shape, and can be used to examine abnormal numbers or structures of chromosomes.
B. A set of unique physical characteristics that define an individual
C. The collection of all the mutations present in an individual.
D. None of the above.
_______ 8. Which of the following changes in chromosome will happen if a fragment from one chromosome joins
to a sister chromatid or homologous chromosome?
A. Deletion B. Duplication C. Translocation D. Inversion
For items 9-14, match the labeled component of the cell membrane (Figure 2) with its description. Write
CAPITAL letter of your choice.

______9. peripheral protein

______10. cholesterol 
______11. glycolipid
______12. glycoprotein
______13. cholesterol
______14. transmembrane
_______ 15. Which of the following types of 
molecules are the major structural 
components of the cell membrane? 
A. phospholipids and cellulose
B. nucleic acids and proteins  Figure 2
C. phospholipids and proteins
D. proteins and cellulose
______16. Which of the following is the hydrophilic part of the cell membrane?
A. cholesterol B. ‘tail’ C. phosphate head D. lipids
______17. Which of the following proteins act as passageways for molecules, such as water, to pass through
the cell membrane quickly?
A. channel proteins B. carrier proteins C. protein pump D. none of the choices
______18. Which of the following is true of integral membrane proteins? 
A. They lack tertiary structure.       B. They are not mobile within the bilayer

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 C. They are usually transmembrane proteins.       D.
They are loosely bound to the surface of the bilayer.
______19. Which of the following would likely move through the lipid bilayer of a plasma membrane
most rapidly? 
A. CO 2 B. an amino acid C. glucose D. K
+

______20. Which of the following is the function of cholesterol in the plasma membranes of some animals?

A) makes the membrane less flexible, allowing it to sustain greater pressure from within the cell.
B) enables the membrane to stay fluid more easily when cell temperature drops. 
C) enables the animal to remove hydrogen atoms from saturated phospholipids. 
D) enables the animal to add hydrogen atoms to unsaturated phospholipids.

II. Analyze the following karyotypes and complete and answer the given questions.
A. 1. What is the gender of 
   the person?
2. What is the total number 
    of chromosomes in this
    karyotype? 
3. Normal or Mutated?
If mutated, name the disorder

B. 1. What is the gender of 

   the person?
2. What is the total number 
    of chromosomes in this
    karyotype? 
3. Normal or Mutated?
If mutated, name the disorder

C. 1 What is the gender of 

   the person?
2. What is the total number 
    of chromosomes in this
    karyotype? 
3. Normal or Mutated?
If mutated, name the disorder

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