arterie

suallyhard
arterial a l AN
NTN e
luminal narrowing
The abdominal aorta is
hardeni
a media. -
he artertes ari
ehr sd arenes ani peripheral
angr
Causesof
miuSular v x l s may

arternal brara:thes
ffecte
e invohoscerotie
be le tunica n
iron an

Ned around
e l uniershni ut ne ar
the oritsot
ences as io
h a e m o n d V n a m * intuences b arterioscler
been
are i i

wher sSuge
arternal brarhing sites Ateria
e is arurreme atthe
equent the sub
emt
d
blood no harr

Gs the esns are sen as shghty raisei fim nhite plaques. Micr Inflam
heinma
o i e r a b o n of
is thickened by
smavth musce cells in
aIumulation ot
the tunca media and
scopi
opolysaccharides e
, anda Arterit

m the intima Splitting and tragmentationot the internal fibrou Arteri

nimto
internal elaste
elasticclami (1) vir
bluetc
Aheroscierosis perito
Haem
disease is of the
animals and greatest importance in human sper
ne
rarely causes clinical disease, beings. t is dirof
bran The main such as
us
aiteration is the accumulation ot intarction of t
vessel walls whichdeposits (atheromal o
tssue. and calcium in upu:
go the lumen.
a s

ebie
to e
Many studies have shown
that the pig, ultimately esults n
experimental
The dog, cat, disease rabbit, and chicke
cow, goat, and produced by the
s at nauraly
the rat are
resistant. feeding of a high
nd
dng wth occurring disease have been
es hypothyroidism
heart which is
mesentery, and kidneysassociated
found in aged
with pigs and brds
Microscopi
els and cally, ipid
cn
globules
are
markedlyhvpercholesterolaemia
ecis and
macrophages,
tibrosis often ulate thickened,
accumulate hickened, fim,
in
firm, and
the cytoplasm of
Anes Meda Caicification develop called 'foam
Tis
some in
arteries. cells' in the cytoplasu
media and int
aor
men
iesion
meua
atd in
volves bothanimals. It is
elastic and usually
muscularassociated
ciated
arteries.
with
with endocard
end
leu
me
94 The
ne causes inci
caus