STUDENT NAME:_________________________________________SECTION:____________

Activity 4: Inflammation Crossword Puzzle. The following entries are all about the different terms related to the processes and
concepts in inflammation. Enjoy and engaged in a mental calisthenics.
HAPPY LEARNING!!!
NOTE: The earlier you submit the higher grade you get. EITHER PRINT OUT, ANSWER, SCAN and SUBMIT or DIGITALIZED ANSWERS
then SUBMIT.

Across
2 Acid-fast bacilli in macrophages, non- caseating
granulomas. Leprosy
8 Microscopic to visible lesion, enclosing wall of histiocytes,
plasma cell infiltrates, necrotic central cells without loss of
cellular outline seen in syphilis.
10 Inflammation characterized by infiltration with
mononuclear cells, tissue destruction and repair involving
angiogenesis and fibrosis. Chronice
15 Predominant form of leukocyte during 24-48 hrs after the
onset of inflammation. Monocytes
17 Cells with pink, granular cytoplasm with indistinct
boundaries considered as a hallmark of granulomas.
Epithelioid Cells
Down
1 Type of morphology of inflammation is manifested by
the presence of large amounts of purulent exudate
consisting of neutrophils, necrotic cells, and edema
fluid. Suppurative
3 A macrophage with ingested microorganism fused
with lysosome is called _______. Phagolylosome
4 Process of coating microorganisms with proteins that
facilitate phagocytosis. Opsonization
5 The process of luekocyte accumulation at the
periphery of blood vessels is called ______.
Margination
6 A short-lived, soluble, free-radical gas produced by
endothelial cells causing smooth muscle relaxation
19 The molecule in the endothelium responsible for this
stage of vascular inflammatory response Rolling. Selectins
20 Enzyme inhibited by glucocorticoids. Phospholipase
21 Type of morphology of acute inflammation characterized
by the outpouring of watery, relatively protein-poor fluid
derived from the serum or endothelial lining of peritoneal,
pleural, and pericardial cavities. Serous
22 A focus of epithelioid cells, rimmed by fibroblasts,
lymphocytes, histiocytes, occasional giant cells. Non-
caseating Tubercle
23 Inflammation which is characterized by plasma protein
exudation and a predominantly neutrophilic leukocyte
accumulation. Acute
24 Initial vascular response to injury. Vasoconstriction
27 The most important lysosomal enzyme involved in
bacterial killing. Elactase
28 It is a protective response intended to eliminate the initial
cause of cell injury as well as the necrotic cells and tissues
resulting from the original insult. Inflammation
31 Central amorphous granular debris, loss of all cellular
detail, acid-fast bacilli. Caseating Tubercle
33 Syndrome that results from a defect in the protein
involved in membrane docking and fusion. Chediakhigashi
35 This activated component of the coagulation cascade
initiates four systems involved in the inflammatory
response, namely the kinin, clotting, fibrinolytic and
complement systems. Hageman Factor
38 Enzyme blocked by NSAIDS. Cycloxygenase
42 The lymphocytic adhesion molecule counterpart of this
endothelial receptor P-Selectin. Sialyl-Lewis X
and vasodilation. Nitricoxide
7 They are a family of small structurally related proteins
that act primarily as chemoattractants for different
subsets of leukocytes. Chemokines
9 A peptide Leukocyte granule constituent which kills
microbes by creating holes in their membranes.
Depensis
10 Occasional non- caseating granulomas in intestinal
walls, with dense chronic inflammatory infiltrate.
Crohh’s Disease
11 Type of morphology of acute inflammation that
histologically appears as an eosinophilic meshwork of
threads or sometimes an amorphous coagulum.
Fibronovs
12 Macrophages in the liver. Kuffer Cells
13 Polypeptide products of many cell types that function
as mediators of inflammation and immune response.
Cytokines
14 It is the cytolytic end product of the complement
cascade, which forms a transmembrane channel
causing osmotic lysis of target cells. Membrane Attack
Complex
16 An ultrafiltrate of blood which contains little protein.
Transupate
18 Cells that are 40-50 um in size, consisting of a large
mass of cytoplasm and many nuclei. Giant Cells
25 One of the major cytokine in acute inflammation. TNF
26 NADPH deficiency or defect resulting in decreased
oxidative burst. CGD
28 The endothelial adhesion molecule responsible for
this stage of vascular inflammatory response of
Intercellular adhesion. Icam
29 Predominant form of leukocyte during the first 6 - 24
hours of inflammation. Nevtrophils
30 Fluid accumulation in extravascular space. Edema
32 The lymphocytic adhesion molecule counterpart of
this endothelial receptor CD-31. CD
34 The lymphocytic adhesion molecule counterpart of
this endothelial receptor ICAM-1. Integrins
36 Process of leukocyte migration toward sites of
infection or injury along a chemical gradient.
Chemotaxis
37 The molecule in the endothelium responsible for this
stage of vascular inflammatory response of
Transmigration. Pecam
39 Fluid in a serous cavity is called ______. Effusion
40 Focal collections of pus that may be caused by seeding
pyogenic organisms into a tissue or by secondary
infections of necrotic foci. Abscess
41 It is an excavation of the surface of an organ or tissue
that is produced by necrosis of cells and sloughing of
inflammatory necrotic tissue. Ulcer
43 Results from increased vascular permeability, leading
to leakage of protein into tissues. Exudate