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Cha11ter-3 / 3J - 3
ADU'- TERATION AND EVALU ATION OF DRUGS
(3Jl~fQ11J cJiT ~ 11(.Yi - - )
11
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uJ ~11h,,1l1111l<111 hJ ,\tpnd1~ge ,
bJ~
,.. , Adiilf~, 11 ,1/ln dJ Detenoniuon
d;ITTF.
iH an ndmlx1ure or
&uhlili tution of
!/ ~; m;l;;; ~irnui. wlrh Rpuriowi , inferior, defective,
2) _ _ _ _ 'ifiT ~ mTf 11T g;f.:.1;•r1F, '1>..·
cfi TIT~ qr ~flf4¢ -3 IT~ ~ ~JWJT 71' ~ . : , ; -~--~
11 ~f' lr1111, or h11rmf11l 1tuh1w:inceli .
,tl Ad11llt: ru li11n aJ f'i<1rqc b) ~ ·
h) Sublititution
'-' ) Spollugt: d) Admixture CJ j4', m1 dJ ~,w,r
11 _ --~-- 111 lmpalrment in drug quality. 3) - - - - ~qfr 7JUWTT if ITTf.1 g
lnfel'iorl ty
11) b) Sophi1,tication a) ift';@T bJ pt)Zfa l
c) Admlx lure d) Deterioration c) fff~ dJ ~
_ _ _ _ __ iN defined as intention..11 type of 4) - - -- - - &tUfj'(iiQ ~ ¢1 ~ ~ ::
ll(Julferution . ~fc)m rrrmt 1
Spulluge
11) h) Admlx1ure a):f~ b) ftl,!;fUf
c) Sophl Nllcutlon d) lnferiorily c) 'l1~1-Jct r d)~
~ ......---- - lHru.ldillon of an entirely different 5) - - - - ~ ~ ~ ~ ~ ~ ~-;:-
1mb.,11111ce lmilead of' the oriiinal drug. 3R17TQ<TTclq,f<TT7T tl
u) A~mlx tul'c h) Substitution
a) fffwrr b) ~
e,; ) Inferiority d) Spoilage
c) ITTill d) j¢f! l'1
- - ~ ~ - i.11 addition of any substandard drug .
lnfo rlority
11) b) Admixture
6) _ _ _ _ ~ ~ G<TT cfiT ~ tI
r) Spul lagt d) Substitution a) ITTill b) ftlwrr
c) jcf;fil-1 d)~
7l ~ - ~- is accidental addition of one objc<.:t
into nnolher due to ignorance or carelessness. 7) _ _ __ ~ m c11q~ql6l ~ cf>RUT ~
n) Jnteirlol'ily b) Substitution ~ cJ;T ~ ff 611¢R:iich ~ I t
c ) SpolJ11ge d) Admixture a)rnfil b)~
X) _ _ __ _ occurs as a rcsull of microbial c) jchfil1 d) f?f~
ftll{lC.k,
11) Substitution b) Spoilage
8) - - ~ ~ 3IBf)liUT $ qR0111·1f<lfiQ mm t ,
a)~ b) jchf!l1
c..:) Inferiority d) Admixture
c)~ d)f?f~
'J) Naaunsur have a two-celled ovary, while the
spurious fl owers have a _ _ __ celled ovary.
9) -illl<f>fl~ ~ ~-cffl~lcf;I cJB ~ ~ ~. vfefcti '¥
u) TripJe h) Double ~ ~ ~ - - cnl~lcf>I ~ ~ mm~ I
C) Single d) Quadrant a)~ b)~
c) ~ d) 'qgcl
I()) If appropriate conditions of collection, transportation,
and ldcntHication are not maintained, accidental 10) ~ ~ . qfQq151 ~ ~ ~ ~ ~ CfiT
adukeration can occur, which·is tenned as _ _ __ ~ ~ ~ vrrm 611c1>f°f'1ch ~ t m m
u) Substitution ~t_ ~--_'P NvfTIT Ttl
h) Spoilage a)~
c) Deteriorntiou b) jcf>f!l1
d) Uodelihcrllle adulteration c) ITTfl'
I I) evaluation of a drug involves d) 3l4fmch f?tc11qc
determining iti; colour, odour, taste, size. shape,
louch, tex tttrc, etc. 11) ~ - rt - - 'j_<"'-liifi'i ~ ~ • . JWfiR,
n) Physicnl b) Organoleptic
xll', TftT, "fcfR cf~ 'fi"q ~ fcnlTr vTTm I t
a)~
c) Chcmicul d) Biological b) '<'i4k1iifi
c) ~lf!ll!Plifi d)"GT~
pharn1acognosy
C-107
12) . th is a qualitative
which e morphological nd evaluation t .
drtJgs are studied. a sensory char Ype in
acters of
12) . ~ '],Dllciicf> 4i~icf>~ Wf>R ~ ~
a) Biological b) Ch . GCTT3TT ~ '(ii41~cfi ~ ·~ <'fa:TUTT "cf>T 3lunA"
. enuca1 ~ \ilRfT t1
c) Organo lepttc d) Ph ys1cal
.
a) ~fctq, b) '11tllllPlcf>
13) - - - - - are of different fo c) '(ii91~'1cfi d)~
the plants for storing food. nns and are used by
13) ~
a)Flowe~ b)Le ~-"9't"~ ~ ~ tkw11~ "ffm t
c) Barks aves . til!ITx'T~1'.fTGR~~~tl
d) Underground a)~ b)~
structures
I4) A - - - - - contains all th c) ~ d ) ~ '<1'1-tF11q
organs originating from a node e photosynthetic
O 14) ~ - - - ~ ~ ~ cR 1R ~ TfTo1 ~
a) Simple leaf b) C . n a stem.
~ ffi ~ ~ >fq;Nf ti~Jl'lch 3trT ~ ~ I
c) Compound leaf d) S onifer leaves
heath leaves a)~~ b)~a,1ffi'r
c) ~ ~ d) 3TTcRUT 1ffi'r
J5) How many leaflets are present in
a) Five b) N a compound leaf? 15)~~~~"4?lcJ>~~t1
T umerous
c) en d) Twelve a)"91'q b)~
c)~ d)~
16) - - - - - are the reprod •
found in a variety of form ductive plant parts 16) - : : - - - - - ~-tfim ~ ~ 3TTf met t "GIT
plant in different manners. s an also grow on the ~ ~ "if ~ '1fIB t ~ ~ ~ ~
a) Fruits b) Seeds
-cftm
1R '31"IB t I
a)~ b)~
c) Flowers d) Bark
c)~ d)mc;r
17) - - - - - - globular-, oblong-, or ellipsoidal 17) _ _ _ _ _ •l~&llcf>I( ~lll<'11cf>l'1 <TT ~O::Slcf>li/.
shaped ~lant p~s having seeds are often specialise~ 3TTcf,N~ti'rilcf@~ll3lcfffi~~~
to help m seed dispersal. ~m~~~~tl
a) Flowers b) Fruits a)~ b)~
c) Seeds d) Bark c) ~ d) mc;r
19) _ _ _ _ _ _ fruits develop from a single carpel 19) ::::~~~=-- ~ ~ ~ ~ m !°fict>cf>t c\-l-1
•11~-11~<.1'1 ~ fclq;ffta ~ i 1
or from syncarpous gynoecium.
a)~ b) ~
a) Aggregate b) Simple
c) ~ d) 31~c.:w'n&1
c) Compound d) Indehiscent
20) _ _ _ ~cnl~~~~~
20) ______ fruits are categorised into dry and
~ fcnm \I{lcTT t. "GIT~~ 1lx ~ ~
fleshy fruits based on whether the mesocarp is dry or
~ fct> ~fllcf>lll ~ m ~ t 1
fleshy.
b) Compound a)~ b)~
a) Aggregate c) ~ d) ~rT'flt>.,..."'-.-c.-\~~...,..'n~<:1
CJ Simple d) Indehiscent
21 J _ _ _ _ _ _ fruits develop from more than one 21) =:::~::;:::;=- ~ ~ ~ ~ ~ <TT '-,!ll\cfilc\-l-1
carpels or apocarpous gynoecium. •11~.-fl~llli "fl fclq,ffta ~ ~I
a) Compound b) Aggregate a)~ b)~
c)~ d)~=,&,~"'c~..,~~~~=e1
c) Simple d) Indehiscent
22) _ _ _ _ _ fruits develop from numerous 22) - - ~ ~ "W!T ~ ~ IDxT Pclcf>ffta ~ ~ I
flowers combined together. a)~ b)~
a) Simple b) Aggregate c) 3l~c.-\~C'1 d) ~
c) lndehiscent d) Compou
nd
~ \
-----
ac::01..tu of ....- ~ ~
i.) ~ t i c ~ cdl, ~ by ' ~
c ) ADl~"tic
• b)
d) P'a'ae)lic
.
~I\ Which ot
the fulJo,,a. ·
Anisoqtic
•---•?
&) Spear.
,-mg pbnt has
.... ,.;:,"tic
mml b) Vasan
c ) Damn. d ) Digiwis
Chapter-4 / 3T -4
SECO NDAR Y META BOLIT ES (
_ _ _ _ are heterocyclic nitrogenous compounds.
I) _ _ _ _ _ rf1$~1'11rf cfi fclt4Sl-q¢61ll ~ tI
I)
b) Terpenoids a) '-1C'i:6&11$~fl b) o<tl-ll~~fl
a) Alkaloids
c) Glycosides d) Tannins c) •&11$cf>lfl1$-s d)~
2) In 1805, the first therapeutica lly useful alkaloid, 2) 1805 "Jl, ~ fM<hctflll ~ ~ '34q),ft . .-q<4>--.>--n-<11~.......'5,
_ _ _ _ _ isolated from Papaver somniferum was ~ fl1fl.:i~i<li ~ ~~ ~ 7fll'T m1 _ _ _ I
introduced. a)~ b) '-1~1lfH
a) Cocaine b) Atropine c) frtcf>ll°erf d) ~
c) Nicotine d) Morphine
3) ~;;;;:;;;;;- ~ tj')m ~ ~ '11~~1'11'1-~ 1@
_ _ _ _ _ gave the name alkaloids to nitrogen-
3)
4lfrlct>'i q;l' qW>&ii~~fl ~ ~ m I
containing basic compounds , obtained from plants.
a)~ b)~~
b) W. Meissner
a) Galen
c) C.A. SeydJer d) Ladenburg c) "ffi:~. mm d) ~-%rfiPf
35) _ i s th~ general method of glycosides extraction. 35) - - 1C'll~ctih1I~-$ P,1:q5~o1 qft ~ ~ I t
a) Expression b) Stas-Otto a)~ b) ~--3lTcl
c) Steam distillation d) Chemical method c) ~ 3lRfcR d) '<l'filll P, cf> ~
36) 1C'll~qlh11~-& ~ '1cTT cfiT fc1("!14cf> cfi ~ 11 - -
36) The glycoside-containing drug is finely powdered q~t4qDj ct!' ~ mi
q)f ~ ~ ciflT@R ~
and extracted by continuous hot percolation method
using _ _ _ __ as u solvent.
a) Alcohol b) Chloroform ~~~ vITTTT !~) cM1~14>14
c) Benzene d) Ether c) ~ d) t~
37) ~'11Plctie1 qm l) ~ ~ 'llT _ _ ~ ~
37) A pink or - - ~ - - colou.r appears in the
ammonical layer which confirms the presence of <fc'fT \ill ◄ 14~,1~ -crt)a,oy ct, ~ ~~lfcM"l1'1 ctr
t
anthraqulnone moiety during Bomtrager's teKt. llT? ff~~ cm ~~t ,
a) Blue, b) Red u) ~ b) ~
c) White d) Brown c) ~ d) ~
-qt~ ll, - - 1<'1l~cti' l~11~ -s ctr
38) In Haemolysis test, RBCs will gel ruptured due to the 38) ~«1'<iC14"1
presence of _ ~ -- - glycosides. ~cff~RBC~~I
11) Saponin b) Anthraqulnone a) ~ b) ~~rfcN111
c) Triterpenoid d) Cardiac c) ~tGc::~.-,'h~\S d) ~
alycoliides?
m-m-qt~ ~ ullffl t?
a) ~ 'tlt&l"T b) til~1q lffi ~~
a) Legal test b)j Snlkowaski test
c) ~cmifiWM ~~ d) ~ ~&lUT
c) Haemolysis test d) fioam test
40) f)ii.:,~Rgc:1 l) ~ ~ - m ~ z~1f4:q1l1
40) Which of the following tests is performed for
1C'll~'l11fll.:S cfi ~ ~ vf@l t?
unthraquinone glycosidos?
b) 8orntrager's test a) ~cmt161<F1 -qt~ b) f.il4~•j'( qt~
a) Haemolysis test
Foam test d) Salkownski test c) Ql1lf 'tltafl1T d) fll~1q l~ 'tltWJT
c)
41) Chemical test for coumnrin glycm,ide is 41 > ~ •<'-IIG<t>ltire ~ ~ fffi/ ~1flt4Plcf> Gt~ _ t1
II) ARI ~ ~ llfta:rur b) ~ <RI ~<'1 <Fi trf!WJT
a) Fluorescence test h) Haernoly Nis test c) · til('Cf> lqi~ tltWJT <I) ~ ~efOT
Salkowaski te11t d) Pomn test !1
c)
42) ~ .fl~ ~~ cm '<l'til4Rl <ti ~lffOT _
42) Chemical test of tlavonoid glycosidos is - - -- n) ARI c?l~ 'tltWJT b) ~ ~Wll
a) Fluorescence test b) Buljet test C) 3fll1Frim ~Wll d) ~ ~aTUT
c) Ammonia .test d) Legal ttsl
C- 114
67
) - - - - - are the hydrocarbon secretion of
coniferous trees.
a) Tannins b) Resins
c) Glyoosides d) Volatile oils
68) Ginger is obtained from
a) Guaiacum officinale Linn -----
b) Cannabis saliva Linn
c) Pinus po/ustris Miller
d ) Zingiber officinale Roscoe
69) Cannabis, belonging to family Moraceae, contains
- - - - - in their glandular hair.
a) Resins b) Tannins
c ) Alkaloids d) Glycosides
70) Production of resins takes place in the ducts and
- - - - present in the plant
a) Xylem b) Cavities
c) Phloem d) Fibres
71) - - - - - - resin results in deep blue
colouration of the solution.
a) Colophony b) Alco
c) Guaiacum d) Gum
72) Podophyllum produces _ _ _ _ _ _ action.
a) Laxative b) Purgative
c) Sedative d) Anthelmintic
73) Asafoetida acts as a
a) Sedative
-----
b) Antbelmintic
c) Laxative d) Purgative
74 ) Cannabis acts as a _ _ _ __
a) Purgative b) Sedative
c) Laxative d) Anthelmintic
*Answers ~-tii<'tltwtl)*
1) a 2) d 3) b 4) a 5) a 6) b 7) C 8) b 9) d IO) a
11 ) d 12) a 13) b 14) C 15) b 16) C 17) d 18) C 19) C 20) d
2 1) b 22) a 23) d 24) b 25) C 26) d 27) a 28) b 29) C 30) C
31 ) b 32) d 33) b 34) d 35) b 36) a 37) b 38) a 39) a 40) b
4 1) a 42) C 43) d 44) C 45) b 46) a 47) d 48) b 49) C 50) b
51 ) C 52) b 53) C 54) b 55) C 56) d 57) a 58) b 59) b 60) C
6 1) b 62) t1 63) b 64) d 65) C 66) a 67) b 68) d 69) a 70) b
7 1) C 72j b 73) C 74) b