Laboratory Exercise in Drug Delivery System

Divided Powders

Powders are mixture of finely divided drugs or chemicals in a dry form for internal or external
use. They have good stability than liquids and are useful for bulky drugs with large doses.

Objective
- To prepare divided powders

Materials
- Salt (in lieu of aspirin) Flour (in lieu of lactose)
- Weighing scale White paper
- Mortar and pestle (use an alternative that is available in your home)
- Pill tile (use an alternative that is available in your home)
- Spatula

To make 10 paper tabs

Formula
Aspirin--------------------------------3g
Lactose-------------------------------5g

Procedure
1. Weigh the aspirin and lactose accurately
2. Triturate the two powders
3. Mix the two ingredients using spatulation method
4. Place the powders on a pill tile and use block and divide method, making sure
they are equal in thickness and in height
5. Divide into required quantity
6. Wrap in individual white paper
7. Place in appropriate container
8. Label the container

Worksheet
Laboratory Exercise in Drug Delivery System

Name: ______________________________________ Date: ____________

Group Number: _______________________________ Score: ____________

Divided Powders

Synonym:

Use of the Preparation

Formula for 250 ml

Ingredient Quantity Physical Description Use in formula

Computation

Method of Preparation:________________________________________________

Appropriate Container for the Preparation:_________________________________

Description of the Finished Product:______________________________________

Recommended Storage Condition: _______________________________________

Laboratory Exercise in Drug Delivery System

Questions
1. In preparing powders, what are the steps to be followed?

2. Comminution is an important process in the preparation of powders. Which comminution

technique is applied in this exercise?

3. What advantages do powders offer as to compared to other dosage forms?

4. What instructions are to be given to patient on the proper administration of powders?

Conclusion
Laboratory Exercise in Drug Delivery System