Name of Dosage, Mech.

of Action Indication Adverse Nursing

Drug Route, Reactions Responsibili
Freq., ties
Timing
Generic: Dosage: Acts on the Furosemide is CV: circulatory >Observe 6
furosemid 40 mg ascending loop indicated for collapse rights in
e (Rx) (1 tab ) of Henle in the the treatment giving
kidney, of edema GU: renal failure medication
Brand: inhibiting associated
Lasix Route: with HEMA: >Test if the
reabsorption of
Oral congestive Thrombocytope patient is
electrolytes nia,
heart failure,  allergic to
sodium and agranulocytosis,
Edema due to the drug.
Frequen chloride, causing cardiac, leukopenia,
cy: excretion of hepatic & neutropenia. >Monitor
BID sodium, calcium, renal disease, weight,
magnesium, burns; mild to INTEG: Stevens- blood
chloride,water, moderate Johnson pressure,
Timing: and some HTN, syndrome,
and pulse
Every 12 potassium; hypertensive rate
hours crisis, acute SYST: Toxic
decreases routinely
heart failure, epidermal
reabsorption of necrolysis with long
sodium and reduced
term use
urinary
chloride and and during
output due to
increases rapid
gestoses,
excretion of dieresis.
chronic renal
potassium in the failure, Use can
distal tubule of nephrotic lead to
the kidney; syndrome. profound
responsible for water and
slight electrolyte
Classificati antihypertensive Contraindicati Side Effects:
depletion.
on: ons:
effect and
Functional peripheral Anuria,  low blood >If oliguria
: hypovolemia, pressure, or azotemia
vasodilatation.
Loop hypokalemia.  dehydrati develops or
diuretic Inhibit on and increases,
reabsorption of Contraindicat
electrolyt drug may
sodium and ed in patients e need to be
Chemical: hypersensitive depletion
water in the stopped.
ascending limb to drug and (for
Sulfonami those with example, >Monitor
of the loop of
de anuria. Use sodium, fluid intake
Henle by
derivative cautiously in potassiu and output
interfering with
patients with m). and
the chloride
binding site of hepatic  jaundice, electrolyte,
cirrhosis and  Loss of BUN, and
the 1Na+, 1K+,
 in those hearing,
allergic to ear pain,
sulfonamides. tinnitus,
Use during  blurred
pregnancy vision
only if /sensitivi
potential ty to light
(photoph
benefits to
obia),
mother clearly
 rash,
outweigh
risks to fetus.
 pancreatit
is,
Precautions:  nausea,
Pregnancy C,  diarrhea,
diabetes  abdomina
mellitus, l pain,
dehydration, and
2Cl- cotransport severe renal dizziness. carbon
system. Loop disease, Increased dioxide levels.
diuretics increase cirrhosis, blood >Watch for
the rate of delivery ascites, sugar and signs of
of tubular fluid hypersensitivi uric acid hypokalemia,
and electrolytes to ty to levels such as
the distal sites of sulfonamides, muscle
hydrogen and breastfeeding, weakness and
potassium ion infants, cramps.
secretion, while electrolyte
plasma volume depletion
contraction
increases
aldosterone
production. The
increased delivery
and high

Source:

Skidmore-Roth, Linda. (11th Edition). Mosby's drug guide for nurses. Elsevier publisher.