Vitamin K is used as an antidote for overdosage of coumarin and indandione oral anticoagulants. It reverses hypoprothrombinemia caused by oral antibiotics, quinidine, and other drugs or conditions that inhibit vitamin K absorption and synthesis. Adverse effects include hypersensitivity reactions and fatalities from intravenous injection. Nurses must monitor patients closely, perform baseline and frequent coagulation tests, and adjust therapy based on PT/INR results.
Vitamin K is used as an antidote for overdosage of coumarin and indandione oral anticoagulants. It reverses hypoprothrombinemia caused by oral antibiotics, quinidine, and other drugs or conditions that inhibit vitamin K absorption and synthesis. Adverse effects include hypersensitivity reactions and fatalities from intravenous injection. Nurses must monitor patients closely, perform baseline and frequent coagulation tests, and adjust therapy based on PT/INR results.
Vitamin K is used as an antidote for overdosage of coumarin and indandione oral anticoagulants. It reverses hypoprothrombinemia caused by oral antibiotics, quinidine, and other drugs or conditions that inhibit vitamin K absorption and synthesis. Adverse effects include hypersensitivity reactions and fatalities from intravenous injection. Nurses must monitor patients closely, perform baseline and frequent coagulation tests, and adjust therapy based on PT/INR results.
(Generic name, MECHANISM INDICATIONS CONTRAINDICATIO ADVERSE EFFECTS RESPONSIBILITIES/ brand name, OF ACTION NS OF THE DRUG PRECAUTIONS classification, dosage, route, frequency) Generic Name: Fat-soluble Drug of choice as Hypersensitivity Body as a Whole: Monitor patient Vitamin K naphthoquinone antidote for to Hypersensitivity or constantly. Brand Name: derivative overdosage of AquaMEPHYTON anaphylaxis-like Severe Phytonadione chemically coumarin and reaction: facial flushing, reactions, Classification: identical to and indandione oral Severe liver cramp-like pains, including Vitamins with similar activity anticoagulants. disease convulsive movements, fatalities, have as naturally Also reverses chills, fever, occurred during Route, Dosage & occurring vitamin hypoprothrombine diaphoresis, weakness, and immediately Frequency: K. Vitamin K is mia secondary to dizziness, shock, after IV injection Intramuscular, Term essential for administration of cardiac arrest. CNS: babies 1mg IM soon hepatic oral antibiotics, Headache (after oral Lab tests: after birth biosynthesis of quinidine, quinine, dose), brain damage, Baseline and blood clotting salicylates, death. GI: Gastric frequent Preterm babies Factors II, VII, IX, sulfonamides, upset PT/INR. <1000g, 0.5mg IM and X. excessive vitamin soon after birth A, and secondary to inadequate Frequency, absorption and dose, and synthesis of vitamin therapy duration K (as in obstructive are guided by jaundice, biliary PT/INR clinical fistula, ulcerative response. colitis, intestinal resection, prolonged hyperalimentation). Also prophylaxis of and therapy for neonatal hemorrhagic disease.