Phytonadione (Vitamin K) is used as an antidote for overdoses of oral anticoagulants like coumarin and indandione. It works by promoting the liver's synthesis of clotting factors through an unknown mechanism. It is indicated to reverse hypoprothrombinemia caused by oral antibiotics, quinidine, and other drugs. Adverse effects include hypersensitivity reactions, headache, and gastrointestinal upset. Nurses monitor patients for changes in clotting times and bleeding risks after administration.
Phytonadione (Vitamin K) is used as an antidote for overdoses of oral anticoagulants like coumarin and indandione. It works by promoting the liver's synthesis of clotting factors through an unknown mechanism. It is indicated to reverse hypoprothrombinemia caused by oral antibiotics, quinidine, and other drugs. Adverse effects include hypersensitivity reactions, headache, and gastrointestinal upset. Nurses monitor patients for changes in clotting times and bleeding risks after administration.
Phytonadione (Vitamin K) is used as an antidote for overdoses of oral anticoagulants like coumarin and indandione. It works by promoting the liver's synthesis of clotting factors through an unknown mechanism. It is indicated to reverse hypoprothrombinemia caused by oral antibiotics, quinidine, and other drugs. Adverse effects include hypersensitivity reactions, headache, and gastrointestinal upset. Nurses monitor patients for changes in clotting times and bleeding risks after administration.
Drug Data Classificatio Mechanism of Indication Contraindi Adverse Effects Nursing
n Action cation responsibilities
Generic Therapeutic Drug of choice as Promotes - Body as a Before: Name: class: antidote for overdosage liver Hypersensi Whole: - assess vital signs for Phytonadione Vitamin of coumarin and synthesis of tivity to Hypersensitivity baseline data. (Vitamin K) indandione oral clotting Phytonadio or anaphylaxis- - asses drug to Pharmacolog anticoagulants. Also factors by ne like reaction: allergy. ic class: reverses unknown (Vitamin facial flushing, - prepare the drug Brand name: Hormones hypoprothrombinemia mechanism. K); cramp-like pains, properly. Konakion, Mep And secondary to Does not convulsive - explain use and hyton, Phylloqu Synthetic administration of oral reverse -Severe movements, administration of inone Substitutes, antibiotics, quinidine, anticoagulan liver chills, fever, drug to patient and Antidote quinine, salicylates, t action of disease. diaphoresis, family. sulfonamides, excessive heparin. weakness, vitamin A, and Reportedly dizziness, shock, During: secondary to inadequate demonstrate cardiac arrest.. - Monitor patient absorption and synthesis s wide constantly. Severe of vitamin K (as in margin of CNS: Headache reactions, including obstructive jaundice, safety when (after oral dose), fatalities, have biliary fistula, ulcerative used in brain damage, occurred during and colitis, intestinal newborns. death immediately after IV resection, prolonged injection hyperalimentation). GI: Gastric Also prophylaxis of and upset. -Monitor therapeutic therapy for neonatal effectiveness which is hemorrhagic disease.. Metabolic: indicated by Hyperbilirubine shortened PT, INR, mia, kernicterus. bleeding, and clotting times, as well as Hematologic: decreased Paradoxic hemorrhagic hypoprothrombi tendencies. nemia (patients -Be aware that with severe liver patients on large disease), severe doses may develop hemolytic temporary resistance anemia. to coumarin-type anticoagulants. If oral Respiratory: anticoagulant is Bronchospasm, reinstituted, larger dyspnea, than former doses sensation of may be needed. Some chest patients may require constriction, change to heparin. respiratory arrest. After: Skin: Pain at - documentation of injection site, drug administration. hematoma, and - instruct patient to nodule promptly report formation, adverse reactions erythematous (cramp-like pains, skin eruptions convulsive (with repeated movements, chills, injections) fever, diaphoresis, weakness, dizziness, Special Senses: pain at injection site, Peculiar taste hematoma). sensation. -Maintain consistency in diet and avoid significant increases in daily intake of vitamin K–rich foods when drug regimen is stabilized. Know sources rich in vitamin K: Asparagus, broccoli, cabbage, lettuce, turnip greens, pork or beef liver, green tea, spinach, watercress, and tomatoes.
References:
Nursing2020 Drug Handbook eBook: Lippincott ... (n.d.).
Nursing2020 Drug Handbook eBook: Lippincott ... (n.d.).
2011 Nurse's Drug Handbook, 10th Edition - Medical Ebooks Download. (2019, September 20).
Beecham GB, Bansal P, Nessel TA, et al. Lidocaine. (2020).
In: Statpearls (internet). Treasure Island FL: Statpearls Publishing