Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities

Generic Name Pharmacologic Hinder growth of selected - Amoebic hepatic Contraindicated in patients CNS: seizures, dizziness, Before:
Metronidazole Class: microorganisms, including abscess hypersensitive to the drug, sulfonamides, headache >Assess patient’ infection.
Nitroimidazole most anaerobic bacteria - Intestinal aspirin or other NSAIDs; in those with >Watch carefully for edema
Trade Name and protozoa amoebiasis severe hepatic impairment; in pregnanct EENT: Tearing (topical because it may cause
Flagyl, Metric 21, Therapeutic Class: - Trichomoniasis women in their third trimester. Use only) sodium retention.
Noritade Antibacterial Pharmacokinetics - Retractory catuiously in patients with hx of ulcers >Assess pt’s and family’s
Antiprotozoal Onset: trichomoniasis or GI bleeding, advanced renal disease, GI: abdominal pain, knowledge of drug therapy.
Patient's Dose PO: unknown - Bacterial dehydration, anemia, symptomatic liver anorexia, nausea and
500 mg IVTT q 8 hours IV: immediate infection caused disease, HPN, edema, heart failure, vomiting, diarrhea, During:
Topical: unknown by anaerobic asthma and in poor CYP2C9 drymouth, glossitis >Change sites every 48–72
Maximum Dose microorganisms metabolizers. hr to prevent phlebitis
750 mg q 8 hours Peak: - To prevent Derm: rashes, urticarial, ->Monitor site frequently
PO: 1-2 hrs postoperative Cautious Use milddryness, skin irritation for thrombophlebitis (pain,
Minimum Dose IV: immediate infection in >history of blood dyscrasias; seizures or redness, and swelling).
250 mg q 8 hours Topical: 6-10 hours contaminated neurologic problems Hemat: leukopenia > Monitor for
colorectal >severe hepatic impairment manifestations of
Availability Duration: unknown surgery Local: Phlebitis at Iv site hypersensitivity.
250-750 mg - Pelvic Drug Interactions >Discontinue drug and
inflammatory Do not use with cimetidine, Neuro: peripheral report their appearance
Route disease phenobarbital, warfarin, disulfiram, neuropathy promptly upon
IV fluorouracil manifestations of
Patient's Indication: Misc: superinfection hypersensitivity
Prevention of infection in
the patient who is After:
experiencing diarrhea >Tell pt. that metallic taste
and dark or red brown urine
may occur.
>Instruct to complete full
course of therapy.
>Monitor patient since drug
may cause dizziness/ light
headedness.

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M.F.,&Murr,A.C.(2010) use M.F.,&Murr,A.C. M.F.,&Murr,A.C.(2010) M.F.,&Murr,A.C.(2010) M.F.,&Murr,A.C.(2010) Nurses Pocket M.F.,&Murr,A.C. M.F.,&Murr,A.C.(2010)
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