CLAUDIO, TANYA VICTORIA LEAN T.

BSN 2B

NAME AND DOSE, ROUTE, MECHANISM OF INDICATION CONTRAINDICATION ADVERSE/SIDE NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY ACTION EFFECTS
N OF DRUG AND DURATION
OF
ADMINISTRATIO
N

Generic Name: Inhibits First-line therapy of Hypersensitivity, acute CNS: Peripheral Assess laboratory examinations
Isoniazid Dosage: mycobacterial cell active tuberculosis, liver disease, Previous neuropathy;
300mg, wall synthesis and in combination with hepatitis from isoniazid. convulsions; Monitor liver/renal function.
Brand name: 15mg/kg interferes with other agents.
INH metabolism. Prevention of Dermatologic: Instruct patient that compliance
Isotamine Frequency: Bacteriostatic, tuberculosis in Morbilliform, with dosage schedule for duration
Nydrazid Once daily bactericidal patients maculopapular in necessary to gain benefits.
action. exposed to active
Classification: Route: GIT: Nausea; vomiting; Caution patient in alcohol while
Bacterial action disease.
Antituberculars PO, IM epigastric distress in theraphy may increase risk of
against
liver damage.
susceptible
Hepatic:
organisms. Tell patient to report peripheral
Hepatotoxicity,
jaundice neuritis

Metabolic: Pyridoxine
deficiency; pellagra;
hyperglycemia;

NAME AND DOSE, ROUTE, MECHANISM OF INDICATION CONTRAINDICA ADVERSE/SIDE NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY ACTION TION EFFECTS
N OF DRUG AND DURATION
OF
ADMINISTRATIO
CLAUDIO, TANYA VICTORIA LEAN T.
BSN 2B

N
Administer on an an empty stomach, 1 hr
Generic Name: Inhibits RNA Active tuberculosis Hypersensitivity, before or 2 hr after meals.
Rifampicin Dosage: synthesis by (with other agents). concurrent
10mg/kg blocking RNA Elimination of indinavir, Administer in a single dailydose.
Brand name: transcription in meninggococcal nelfinavir,
Rifadin Frequency: susceptible carriers. Unlabeled pyrazinamide, or Consult pharmacist for rifamoin
Rimactane Once a day organisms Use: saquinavir. suspension for patients unable to swallow
Rofact Prevention of capsules
Route: Therapeutic disease caused by
Classification: Oral Effects: Prepare patient for the reddish-orange
Haemophilus
Antitubercular Bactericidal action influenzae type B coloring body fluids (urine, sweat,
Agents against susceptible in close contacts. sputum, tears, feces, saliva); soft contact
organisms. lenses may be permanently stained, advise
patients not to wear them during therapy

Warning: arrange for follow-up visits for

liver and renal function tests, CBC and
opthalmic examination.

NAME AND DOSE, ROUTE, MECHANISM OF INDICATION CONTRAINDICA ADVERSE/SIDE NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY ACTION TION EFFECTS
N OF DRUG AND DURATION
OF
ADMINISTRATIO
N
Ethambutol CNS: confusion,
CLAUDIO, TANYA VICTORIA LEAN T.
BSN 2B

diffuses into dizziness, Be alert for signs of hepatitis, including

Mycobacterium Contraindicated in hallucinations, anorexia, abdominal pain, severe nausea
Generic Name: Dosage: cells.12 Once Ethambutol is patients headache, malaise. and vomiting, yellow skin or eyes, fever,
Ethambutol 1200 mg inside the cell, indicated in who are known to sore throat, malaise, weakness, facial
ethambutol inhibits combination with be EENT: optic neuritis edema, lethargy, and unusual bleeding or
Brand name: Frequency: other anti- hypertensive to this
the bruising. Report these signs to the
Myambutol Daily tuberculosis drugs drug. It GI: HEPATITIS, physician immediately.
arabinosyltransfera
ses (embA, embB, in the treatment of is also abdominal pain,
Classification: Route: pulmonary anorexia, nausea, Instruct patient to report any vision
and embC), contraindicated in
Antitubercular PO tuberculosis. vomiting.
preventing patients with disturbances or eye pain and inflammation
formation of the known optic that might indicate optic neuritis.
neuritis unless Metab:
cell wall
clinical hyperuricemia. MS: Instruct patient and family/caregivers to
components
judgement joint pain. report other troublesome side effects such
arabinogalactan
and determines that it as severe or prolonged headache, fever, or
Neuro: peripheral GI problems (nausea, vomiting, loss of
lipoarabinomannan may be used.
neuritis. appetite, abdominal pain).
, and preventing
cell division. Misc: anaphylactoid
reactions, fever.

NAME AND DOSE, ROUTE, MECHANISM OF INDICATION CONTRAINDICA ADVERSE/SIDE NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY ACTION TION EFFECTS
N OF DRUG AND DURATION
OF
ADMINISTRATIO
N
fever, Assess patient’s condition before theraphy
CLAUDIO, TANYA VICTORIA LEAN T.
BSN 2B

joint pain or and regularly there after to monitor drug

Generic Name: Pyrazinamie gets Used in Hypersensitivity, swelling, effectiveness.
Pyrazinamide Dosage: activated to combination with Cross-sensitivity easy bruising or
15-30mg Pyrazinoic acid in other agents in the with ethionamide, bleeding (nosebleeds, Instruct patient and family/caregivers to
Brand name: the bacilli where it treatment of active isoniazid, niacin or bleeding gums), report other troublesome side effects such
Tebrazid Frequency: interferes with fatty tuberulosos nicotinic acid may stiff joints, as severe or prolonged skin problems
Zynaphar Once daily acid synthase FAS exist; Severe liver redness or swelling (rash, acne, itching), GI problems
I. This interferes impairment joints (especially at (diarrhea, nausea, vomiting, loss of
Classification: Route: with the bacteriums appetite), or difficult/painful urination.
night),
Antituberculotic Oral ability to nausea,
synthesize new upper stomach pain, Advise patient about photosensitivity and
fatty acids, itching, to use sunscreens, protective clothing, and
required for growth tiredness, avoid prolonged sun exposure. Advise
and replication. loss of appetite, patient to also report any rashes or other
Pyrazinamide dark urine, skin reactions.
diffuses into active clay-colored stools,
M. and
yellowing of the skin
or eyes (jaundice)

NAME AND DOSE, ROUTE, MECHANISM OF INDICATION CONTRAINDICA ADVERSE/SIDE NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY ACTION TION EFFECTS
N OF DRUG AND DURATION
OF
ADMINISTRATIO
N
Monitor signs of angioedema, including
indicated for the high levels of Blurred vision. rashes, raised patches of red or white skin
CLAUDIO, TANYA VICTORIA LEAN T.
BSN 2B

Losartan and its treatment of potassium in the (welts), burning/itching skin, swelling in
Generic Name: Dosage: principal active hypertension in blood. difficult breathing. the face, and difficulty breathing. Notify
Losartan 50 mg metabolite block adults and pediatric physician immediately of these signs.
Potassium the vasoconstrictor patients 6 years of renal artery dizziness, faintness, or
Frequency: and aldosterone- age and older, to stenosis. lightheadedness when Assess blood pressure periodically and
Brand Name: Once daily secreting effects of lower blood getting up suddenly compare to normal values to help
Cozaar angiotensin II by pressure. Lowering low blood pressure. from a lying or sitting document antihypertensive effects. Report
Route: position. low blood pressure (hypotension),
selectively blood pressure
Classification: Oral liver problems. especially if patient experiences dizziness
blocking the lowers the risk of
Angiotensin fast or irregular or syncope.
binding of fatal and nonfatal mild to moderate heartbeat.
receptor
angiotensin II to cardiovascular kidney
blockers (ARBs) nausea or vomiting. If treating diabetic neuropathy, establish
the AT1 receptor (CV) events, impairment. baseline electroneuromyographic values at the
found in many primarily strokes
beginning of drug treatment whenever
tissues, (e.g., and myocardial pregnancy. numbness or tingling in
possible. Periodically reexamine these values
vascular smooth infarction. the hands, feet, or lips.
to monitor peripheral nerve function and
muscle, adrenal decreased blood stomach pain. document whether drug therapy delays the
gland). volume. weakness or heaviness progression of neuropathic disease.
of the legs.

NAME AND DOSE, ROUTE, MECHANISM OF INDICATION CONTRAINDICA ADVERSE/SIDE NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY ACTION TION EFFECTS
N OF DRUG AND DURATION
OF
ADMINISTRATIO
N

Generic Name: Dosage: Inhibits the Angina pectoris Contraindicated CNS: dizziness, Monitor the patient carefully. Some
Amlodipine 5 mg movement of due to coronary with allergy to light-headedness, patients especially those with severe
CLAUDIO, TANYA VICTORIA LEAN T.
BSN 2B

calcium ion influx artery spasm amlodipine, headache, asthenia, obstructive coronary artery disease, have
Brand Name: Frequency: across the impaired hepatic or fatigue, lethargy developed increase frequency, duration or
Norvasc OD membranes of Chronic stable renal function, sick severity of angina or acute MI after
cardiac and angina, alone or in sinus syndrome, CV: peripheral initiation of calcium channel blocker
Classification: Route: smoothmuscle combination with heart block, edema, arrythmias theraphy or at time of dosage increase.
Calcium Channel Oral cells, thus other drugs. lactation
Blockers; decreasing Use cautiously Dermatologic: Monitor BP frequently during initiation of
Antianginal myocardial Essential with CHF, flushing, rash theraphy.
Agents contractility and hypertension, alone pregnancy
or in combination GI: nausea,
oxygen demand;
with other anti abdominal
also dilates
hypetensive discomfort
coronary arteries
and arterioles.

NAME AND DOSE, ROUTE, MECHANISM OF INDICATION CONTRAINDICA ADVERSE/SIDE NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY ACTION TION EFFECTS
N OF DRUG AND DURATION
OF
ADMINISTRATIO
N
CNS: Anxiety, Advise patient to notify presciber if pulse
Inhibits stimulation Angina, heart acute Heart failure, confusion, dizziness, rate falls below 60 bpm or is significantly
of beta1 - receptor failure, myocardial drowsiness, fatigue, lower than usual.
Generic Name: Dosage: sites in decreased infarction, atrial Bradycardia Headache
Metoprolol 25 mg cardiac output and fibrillation, atrial <45bpm Be aware that patients who take
myocardial oxygen flutter and CV: Angina, metoprolol may be at risk for AV block
CLAUDIO, TANYA VICTORIA LEAN T.
BSN 2B

Brand name: Frequency: demand. These hypertension. Hypersensitivity to arrythmias,

Lopressor Once a day effects help relieve metoprolol or its orthostatic Be aware that abrupt withdrawal of drug
angina and reduce Some off-label uses components hypotension can precipitate thyroid storm in patient
Classification: Route: blood pressure. of metoprolol with hyperthyroidism or thyrotoxicosis.
Beta blockers Oral include EENT: Nasal
supraventricular congestion, Taste Abrupt discontinuation of drug can cause
tachycardia and Disturbance myocardial is chemia, MI or Severe
thyroid storm. hypertension especially in patient with
GI: Constipation, cardiac diseases.
Diarrhea, Nausea,
Vomiting Check blood pressure an hour or two after
administering the drug.
MS: Backpain,
Myalgia

RESP: Dyspnea

NAME AND DOSE, ROUTE, MECHANISM INDICATION CONTRAINDIC ADVERSE/SIDE EFFECTS NURSING RESPONSIBILITIES
CLASSIFICATIO FREQUENCY OF ACTION ATION
N OF DRUG AND DURATION
OF
ADMINISTRATIO
N
Monior VS and blood glucose levels
Exact mechanism Adjunct to diet Allergy to Endocrine: Hypoglycemia,
Generic Name: Dosage: is not undertood; to lower metformin; CHF; lactic acidosis Check for drug compatibility because many
Metformin 850 mg possibly increases glucose with diabetes drugs interact with oral hypoglycemic
peripheral type 2 (non- complicated by GI: Anorexia, nausea, agents.
Brand name: Frequency: utilization of insulin fever, severe vomiting, epigastric,
Glucophage, Once a day glucose, decreases dependent) infections, severe discomfort, heartburn, Do not discontinue this medication without
Glucophage XR hepatic glucose diabetes trauma, major diarrhea, flatulence consulting your health care provider.
Route:
production and mellitus in surgery, acidosis,
CLAUDIO, TANYA VICTORIA LEAN T.
BSN 2B

Classification: Oral alters intestinal patients serious hepatic Hypersensitivity: Allergic Monitor urine or blood for glucose and
Anti-diabetics, absorption of impairment, skin reactions, eczema, ketones as prescribed.
Biguanides glucose. pruritus, erythema, urticaria
Swallow ER tablets whole; do not crush, cut
or chew

Report fever, sore throat, unusual bleeding

or bruising, rash, dark urine, light-colored
stools, hypo or hyperglycemic reactions.