24.

Software and Firmware Topics

24.6 LIS Connection

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LIAISON XL supports 2 different LIS settings:
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a Complete Protocol, to support all LIAISON XL features;
a Reduced Protocol, to be compatible with most of the existing Liaison
connections.
The Complete Protocol features new data and options (refer to Main UI) in
comparison to those offered by previous Liaison system; otherwise, the Reduced
Protocol offers the same functionalities already available on Liaison, thus limiting the
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traceability measures foreseen for LIAISON XL.
The choice between the two possible configurations depends on the features of the
software used as host. The Reduced Protocol can be implemented using a specific
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combination of parameters and allows to install a LIAISON XL in place of a Liaison
analyzer without introducing any modifications in the existing host interface; otherwise,
any change to the Reduced Protocol creates an hybrid configuration that may require
a change in the host.
So, as a general recommendation:
Implement the Reduced Protocol when a Liaison analyzer shall be replaced
without changes on the host;
Implement the Complete Protocol configuration or any other hybrid setting in all
other cases, every time a new installation shall be implemented or when there is a
need to modify the host in order to use the new features supported by
®
LIAISON XL.

Refer to chapter 28 for a more detailed description of LIS Interface Protocol.

24.6.1 LIS Configuration

Table 24.6-1 shows the Reduced Protocol configuration.
Table 24.6-2 shows the Complete Protocol configuration.
Any change to the values of Table 24.6-1 forces the system in a hybrid configuration,
that shall be anyway reflected into the host features.

Page Sub-Page Element Description Setting

Allows to set the flag type,

according to the number of
digits accepted by the host.
Result flag
System LIS/LAS Possible options: Long
style
Long: result flags are
transmitted as “full size”
string

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 24. Software and Firmware Topics

Short: results flags are

transmitted by a 2
character abbreviation
If enabled, some additional
information are sent to the
host and shall be read on it:

Enable Integral Kit Number;

System LIS/LAS Manufacturer Integral Expiration Date; Off
Record Integral Lot Number;
Calibration ID;
Sample Lane Number;
Sample Tube Position.
Allows to chose if sending to
the host the results
Send
Assay > associated to each replicate
Definition Replicates to No
Calculation and the mean result (Yes
host
setting) or only the mean
result (No setting)
Allows to define the aspect of
the results sent to the host: it
Result is possible to send only the
Assay > aspect for dose (Dose setting), only the
Definition Dose
Calculation host qualitative label (Label
transmission setting) or both dose and
qualitative label (Both
setting)

Table 24.6-1: Reduced Protocol Configuration (“Liaison compatible”)

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Figure 24.6-1: Reduced Protocol Configuration (“Liaison compatible”) – System >

LIS/ LAS window setting

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Figure 24.6-2: Reduced Protocol Configuration (“Liaison compatible”) – Defintion >

Assay > Calculation window setting

Page Sub-Page Element Description Setting

Allows to set the flag type,

according to the number of
digits accepted by the host.
Possible options:
Result flag
System LIS/LAS Long: result flags are Short
style
transmitted as “full size”
string
Short: results flags are
transmitted by a 2
character abbreviation
If enabled, some additional
information are sent to the
host and shall be read on it:
Enable
System LIS/LAS Manufacturer Integral Kit Number Yes
Record Integral Expiration Date
Integral Lot Number
Calibration ID

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24. Software and Firmware Topics

Sample Lane Number

Sample Tube Position.
Allows to chose if sending to
the host the results
Send
Assay > associated to each replicate
Definition Replicates to Yes
Calculation and the mean result (Yes
host
setting) or only the mean
result (No setting)
Allow to define the aspect of
the results sent to the host: it
is possible to send only the
Result aspect
Assay > dose (Dose setting), only the
Definition for host Both
Calculation qualitative label (Label
transmission
setting) or both dose and
qualitative label (Both
setting)

Table 24.6-2: Complete Protocol Configuration

Figure 24.6-3: Complete Protocol Configuration – System > LIS/ LAS window
setting

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 24. Software and Firmware Topics

Figure 24.6-4: Complete Protocol Configuration – Defintion > Assay > Calculation
window setting

Once implemented the LIS configuration, it is necessary to start the connection

selecting Yes option in LIS module drop-down field of System > LIS/ LAS > LIS
subpage.

24.6.2 Connection Scheme

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The LIS connection scheme supported by LIAISON XL analyzer is represented in
Figure 24.6-5. Four different configurations can be deployed: setting the dedicated
option available in System > Settings > Others subpage, it is possible to choose how
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the results of the tests shall be transferred to LIAISON XL archive page
(Automatically/ Manually). In the same way the configuration of the dedicated option
available in System > LIS/ LAS subpage allows to set how the archived results shall
be sent to the host (automatically or not). This flexibility allows end-users to choose
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whether they want to perform a “validation” step directly on the LIAISON XL interface
or in any external device.

The results can be sent to host only from the “Archived” page.

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“Done” or “Archive” LIS

“Failed” page Automatic page Automatic (host)

Result Archiving* System Automatically

(Automatically/Manually) Sends All Results (Y/N)

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Figure 24.6-5: LIAISON XL LIS connection scheme

24.6.3 Troubleshooting

Troubleshooting activities related to LIS connections are supported by two dedicated

records, named ASTM1381 and ASTM1394.
It is possible to enable/ disable each LIS records (ASTM1381 and ASTM1394),
enabling/ disabling the dedicated options available in System > LIS/ LAS > LIS
subpage: in the default configuration, only ASTM1394 is enabled.
The first time a LIS connection is established, D:\LiaisonXL\Data\LIS is
automatically created: then all the log files related to ASTM1381 (C3Bxxxxx files) and
ASTM1394 (C3Rxxxxx files) are stored here. In any case, the easiest way to access
these data is to use the LIS dedicated backup from the Main UI.

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