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comparing
Mental activity
Function: To provide
information to transmit
information to different
neurons; muscles and
glands.
produces the myelin sheath and
functions in repair and regeneration of
damaged nerves
• Point where axon is
not covered by
Schwann cells
• are the gaps
(approximately 1
micrometer in
length) formed
between the myelin
sheaths generated
by different cells.
Morphological
› Unipolar
› Bipolar
› Multipolar
Functional
› Sensory neuron - responsible for converting
various external stimuli that comes from the
environment into corresponding internal
stimuli.
› Motor neuron - Motor neurones are neurones
that carry signals from the spinal cord to the
muscles to produce movement.
› Inter neuron - is a neuron that forms a
connection between other neurons.
Highly specialized intercellular junction
which allow communication by linking
neurons of pathways.
• Terminal bouton
– Not mylinated
– Mitochondria
– Membrane bound
vesicle of
neurotransmitter
• Synaptic cleft
• Presynaptic membrane
– synaptic vesicle
– Voltage regulated Ca+2
gated .
• Post synaptic membrane
Structure of a Nerve
• Endoneurium
• Perineurium
• Epineurium
Oval bodies made of aggregation
of cell bodies out side the CNS
Relay center on neuronal pathway
Epineurium
Two type
› Sensory gnaglia (Somatic ) i.e. Spinal
› Motor ganglia (Autonomic) i.e.
sympathetic ganglia
• Gr. Glia : Glue
• Highly branched cells
that support the neurons
by occupying the space
between them.
• Function
– Provide structural and
metabolic support
• Type
– Astrocytes
– Oligodrndrocytes
– Microglia
– Ependymal cells
Dr Pankaj Maheria 16
Embryological origin:
› Neural ectoderm
Function
› Supporting and
nutritive
› Repair
› Barrier to diffusion
of toxic substance
Star shaped
Perivascular feet
› Blood brain barrier
• Gr. Oligo : Few
Dendrone : tree
• Responsible for
myelination of axon in
the CNS and dendrites
• Single cells : 50 axon
• Location
– Predominate in white
matter
– Much abundant in
gray matter
• Small cells
• Derived from
mesenchymal origin
• Elongated nucleus
• Little cytoplasm
• Fine highly branched
processes
• Immuno stains best
way to see
• Macrophage
monocytes defense
system
Dr Pankaj Maheria 20
• Lining epithelium of
ventricle and spinal
canal
• Cuboidal or low
columnar
• Tightly bounded
Dr Pankaj Maheria 21