Name: Deocel May Villoria Section: G1

ACTIVITY # 12 Aspects of Gene Therapy:

Please refer to the video to answer questions 1 & 2 and describe your answers in
not more than 5 sentences.

Questions:
1. Would you subject yourself for gene therapy without its 100% assurance of
effectiveness or future negative side effects? WHY? (5 pts.)
Answer: Yes, for nothing is 100% assured in medicating someone. As said, people
have different DNA so, it has variation effects to the body. Beside doctors will not
prescribe something that could harm their patients. I would rather try to cure myself
than die without trying. But before all, I will ask first the specialist doctor how my
body will react for such medication, and we will ask for approval from DOH.

2. Should gene therapy be limited to medical concerns only? Or could it be use

for aesthetic purposes? Explain. (5 pts.)
Answer: It should be limited for medical purposes only, for it is too risky. It is too
risky in a way that the medicine is not specifically design for aesthetic. As long as
DOH don’t approve something that it can be used for aesthetic then we must not. The
bad uses of gene therapy could lead detriment to society. And so, before using such
medication should seek first to a specialist.
 3. Concept Mapping: Using a Venn diagram, differentiate the 2 forms of gene
therapy. (10 pts.)

VENN DIAGRAM

SOMATIC GENE THERAPY

GERMLINE GENE THERAPY
 alteration of the
genome of somatic  alterations of the
cells by transferring genome of the germ cell
therapeutic genes. SIMILARITIES by introducing
 Somatic gene therapeutic genes.
*Both Somatic and Germline
therapy uses  uses Germ cells such as
Somatic cells. Gene therapies involve
altering of defective genes sperm cells and egg cells.
 As to
or introducing of healthy  As to reproducibility it
reproducibility it NK
genes. passes into the next
does not passes
into the next *Both therapies use gene generation.
generation. transformation methods.  Germline gene therapy is
 Somatic gene less conservative.
therapy is more
conservative.
 4. Flow Chart: Make a flow chart of the basic process of gene therapy. Explain
each part of the process. You may use other references for your guide. (10
pts.)

GENE THERAPY PROCESS

First. Cells Sixth. Altered cells Seventh. Altered

harvested from injected into cells produce
patient. patient's body. desired protein.

Second. In lab,
Fifth. Cells become
virus altered so
genetically altered.
cannot reproduce.

Third. A gene is Fourth. Altered

inserted into the virus mixed with
virus. patient's cells.