TRISHA COLEEN G.

ASOTIGUE DECEMBER 4, 2023

BSED-ENGLISH 2A

GE STS
ACTIVITIES

1. Flow chart. Make a flow chart of the basic process of gene

therapy. Explain each of the process. You may use references for
your guide.

Replacement of mutated gene that

causes disease with a healthy copy of
the gene

Inactivation of mutated gene

that is functioning improperly.

Introducing a new gene into the

body to help fight a disease.
2. Concept mapping. Using a Venn diagram, differentiate the two forms of gene therapy.

Somatic gene therapy Germ-line Therapy

 Involves the manipulation of gene in

the cell.  Involve modification of the gene
 Not inherited by future offspring inside germ cell.
 Surrounded by fewer ethical  Inherited and be pass to the next
issues. generation
 Doesn’t produce sperm BOTH FORM OF GENE  Can produce sperm or egg cell.
or egg cell. THERAPY  This therapy is very costly.
 DNA transferred in the body  DNA transferred in to the cells.
tissue.  Less conservative
 More conservative  Techniques are very complex since it
 Techniques used are relatively involves fetal sample
simple.  Reproducible
 Can be performed under in vitro
condition
 Non reproducible