Drug order Mode of action Indication Contraindication Adverse effect Nursing responsibility/

Precautions

Generic name: Hydrochlorothiazide a Hydrochlorothiazide Documented  Anaphylaxis  Monitor signs of flu

Hydrochlorothiazid cts on the distal is used to treat hypersensitivity to  Anorexia electrolyte, or acid
e (rx) convoluted tubules edema (fluid hydrochlorothiazide or  Confusion base imbalances,
and inhibits the retention; excess sulfonamides  Disorder of including dizziness
Brand name: sodium chloride co- fluid held in body hematopoieti drowsiness, blurre
Microzide, transporter system. tissues) caused by c structure vision, confusion,
hydrodiuril, hydro, This action leads to a various medical  Dizziness hypotension, or
esidrix, hctz, oretic diuretic action that problems, including  Epigastric muscle cramps an
Drug class: lowers blood heart, kidney, and distress weakness. Report
diuretics, thiazide pressure, but there is liver disease and to excessive or
 Fatigue
Dosage: also a potassium loss treat edema caused prolonged sympto
 Headache
12.5mg in the urine. by using certain to the physician.
25mg medications including  Hepatotoxicit
 Assess dizziness
50mg estrogen and y
weakness that mig
Frequency: corticosteroids. affect gait, balance
Every other day and other function
Route: activities
Oral (see appendix c).
Report balance
problems and
functional limitatio
to the physician, a
caution the patien
and family/caregiv
to guard against fa
and trauma.
 Assess blood
pressure periodica
 and compare to
normal values
(see appendix f) to
help document
antihypertensive
effects.
 When used to trea
edema, help
determine drug eff
by assessing
peripheral edema
using girth
measurements,
volume displacem
and measurement
pitting edema
(see appendix n).
monitor signs of
pulmonary edema
such as dyspnea a
rales/crackles
(see appendix k).
Document whethe
peripheral and
pulmonary sympto
are controlled
adequately by diur
therapy.
 Monitor signs of
hyperglycemia
(drowsiness, fruity
breath, increased
 urination, unusual
thirst). Patients wi
diabetes mellitus
should check bloo
glucose levels
frequently.
 Levels of dofetilide
(tikosyn) and caus
abnormal heart
rhythms. Thiazide
diuretics can redu
how the body
responds to
norepinephrine an
render norepineph
less effective.
Generic name: Rifampin is thought to This medication is a  Diabetes.  Upset
Rifampin inhibit bacterial DNA- rifamycin antibiotic stomach  This medication is
 Porphyria.
dependent RNA used to prevent and  Heartburn taken on an
Brand name: polymerase, which treat tuberculosis and  Decreased blood-  Nausea
Rifadin, appears to occur as a other infections. this clotting from low  Menstrual empty stomach wit
rimactane result of drug binding antibiotic treats vitamin k. changes
 Alcoholism. full glass of water (
Drug class: in the polymerase only bacterial  Or headache 
Antitubercular subunit deep within infections. It will not  Liver problems. ounces or 240
agents the DNA/RNA work for viral
 Abnormal liver milliliters) 1 hour
channel, facilitating infections (such
function tests.
Dosage: direct blocking of the as common before or 2 hours a
Capsule elongating RNA. This cold, flu).   A yellowing of the
effect is thought to be eyes or skin from meals; or take as
 150 mg concentration related buildup of bilirubin
called jaundice. directed by your
 300 mg
doctor. If you
Frequency: have nausea, do n
Daily / AC take antacids
Route:
Oral with rifampin since
will lessen the
effectiveness of thi
drug. However, if y
need to take antac
wait at least 1 hour
after taking this dru

 If you are unable to

swallow the capsu
you may open the
capsule and sprink
the contents onto a
spoonful of cool, so
applesauce or jelly
Eat the entire mixtu
right away. Do not
prepare a supply fo
 future use.

 If you have a liquid

form, shake the bo
well before each d
Use a medication-
measuring device
carefully measure
prescribed dose.

 Rifampin is frequen
used in combinatio
with other antibiotic
prevent or treat ce
kinds of infections
(e.g.,
latent/active tuberc
is, meningococcal
disease). Your
dose/schedule/trea
 nt length will vary,
depending on wha
you are treated for
the best effect, tak
this medication at
evenly spaced time
or exactly as direct
To help you
remember, take th
medication at the
same time(s) every
day.

 Continue to take th
medication until the
prescribed amount
finished, even if
symptoms disappe
after a few days.
Stopping the
medication too ear
may allow bacteria
continue to grow,
which may result in
return of the infecti
Generic name: Xanthine oxidase Allopurinol is used to Hypersensitivity to  Stomach  Discontinue at firs
Allopurinol (rx) inhibitor; inhibits treat gout and certain allopurinol upset sign of allergic
conversion of types of kidney  Nausea reactions (first sign
Brand name: hypoxanthine to stones. It is also  Diarrhea, or rash, vasculitis, or
Zyloprim, aloprim xanthine to uric acid; used to prevent  Drowsiness  stevens-johnson
Drug class: decreases production increased uric acid syndrome, drug ra
xanthine oxidase of uric acid without levels in patients with eosinophilia a
inhibitors;  disrupting synthesis of receiving cancer systemic symptom
vital purines chemotherapy. (dress) and/or
antigout agents These patients can generalized vascu
have increased uric irreversible
Dosage: acid levels due to hepatotoxicity)
Tablet release of uric acid  Take this medicati
100mg from the dying by mouth, usually
300mg cancer cells. once daily or as
Allopurinol works by directed by your
Frequency: reducing the amount doctor.
Daily / pc of uric acid made by  Take this medicati
Route: the body. Increased after a meal to red
Oral uric acid levels can stomach upset.
cause gout and  If your dose is mo
kidney problems. than 300 milligram
day, you will need
take several small
doses during the d
to get this amount
(ask your doctor fo
directions).it is bes
drink a full glass o
water with each do
and at least 8 mor
glasses (8 ounces
 each) of fluid a da
 If your doctor has
directed you to dri
less fluid for other
medical reasons,
consult your docto
further instructions
 Your doctor may a
instruct you on ho
decrease acid in y
urine (e.g., avoidin
large amounts of
ascorbic acid/vitam
c).dosage is based
your medical cond
and response to
treatment.
 Use this medicatio
regularly to get the
most benefit from
To help you
remember, take it
the same time(s) e
day.
 For the treatment
gout, it may take u
several weeks for
medicine to have a
effect. You may ha
more gout attacks
several months af
starting this medic
 while the body
removes extra uric
acid.
 Allopurinol is not a
pain reliever.
 To relieve pain fro
gout, continue to t
your prescribed
medicines for gou
attacks (e.g.,
colchicine, ibuprof
indomethacin) as
directed by your
doctor.tell your do
if your condition
persists or worsen