Interleukin-8,

Mouse Anti-
Human

Catalogue
ANT-111
Number

IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell

chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C,
Synonyms Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil-activating
peptide, MONAP, Emoctakin, K60, NAF, LECT, LUCT, 3-10C, LYNAP, SCYB8, TSG-1,
AMCF-I, b-ENAP.

Type Mouse Anti Human Monoclonal.

Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types

such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in
their storage vesicles, the Weibel-Palade bodies.
When first encountering an antigen, the primary cells to encounter it are the
Introduction
macrophages who phagocytosethe particle. Upon processing, they release
chemokinesto signal other immune cells to come in to the site of inflammation. IL-8
is one such chemokine. It serves as a chemical signal that attracts neutrophilsat the
site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor.

Clone NYR-HIL8.

Immunogen r.Human IL-8.

Ig Subclass Mouse IgG1.

Purification
Ion exchange.
Method

Protein
1mg/ml in PBS (after reconstitution).
concentration

Shipping
Antibody is shipped lyophilized at ambient temperature.
Conditions

Storage In lyophilized form, for long periods, store at 4oC in a dry environment. After
Procedures reconstitution, if not intended for use within a month, aliquot and store at -20oC.

Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60
Reconstitution
seconds before use.

By direct ELISA, 1:20,000 dilution will yield >1.0 O.D using alkaline phosphatase
Titer
conjugated rabbit anti-mouse Ig (Jackson Laboratories).
Applications Direct ELISA, Western Blot, Immuneprecipitation, Immunohistochemistry.

Cross reactivity No cross reactivity with murine IL-8 was detected.

Note This antibody was produced in BALB/c mice.

Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product
Usage may not be used as drugs, agricultural or pesticidal products, food additives or
household chemicals.

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