DOSE,

NAME AND FREQUENCY NURSING

MECHANISM CONTRAINDICATION ADVERSE
CLASSIFICATION ROUTE, INDICATIONS RESPONSIBILIIES
OF ACTION S EFFECTS
OF DRUG DURATION OF
ADMINISTRATION
Generic Name: Dosage: Increases Indications: Contraindications: Metabolic alkalosis, 1. Hypertonic
Sodium Bicarbonate 17 meqs NaHC0 plasma mood changes, solutions must be
3+17 mlSW bicarbonate,  Treatment of metaboli Metabolic or Respiratory tiredness, shortness administered by
Brand Name: which excess c alkalosis; hypernatremia, of breath, muscle trained personnel.
Rhea Sodium Frequency: buffer H ion acidosis; promotion severe pulmonary edema, weakness, irregular Avoid extraversions
Bicarbonate, Hospira NOW concentrations; of gastric, systemic hypocalcemia, heartbeat, muscle as tissue irritation or
Sodium Bicarbonate, reverses and urine hypochlorhydria. hypertonicity, cellulitis may result.
Phil Route: metabolic alkalinization in the  twitching,
Pharmawealth/Atlantic IV Drip acidosis; case of intoxication Drug Interactions: hypernatremia, 2. Administer
Sodium Bicarbonate, neutralizes with weak organic hyperosmolality, isotonic solutions
United Home Sodium gastric  acids; in order to Amphetamines- increase hypocalcemia, slowly; too rapid
Bicarbonate acid, improve the Amphetamines effect by hypokalemia, administration may
which forms  solubility of increase renal tubular stomach cramps, result in death due to
Classification: water, NaCl,  drug substances that  reabsorption flatulence. cellular acidity. Check
Antacid, Antireflux CO2; raises are poorly soluble in rate of flow
Agents and Anti blood ph. neutral acid Antidepressant, tricyclic- frequently.
Ulcerants/ Electrolytes medium; and in the increase TCA effect by
case of hemolysis. increase renal tubular 3. If on low continues
reabsorption. or intermittent NG
sanctioning or
Benzodiazepines- decrease vomiting, assess for
benzodiazepine effect R/T evidence of excessive
increase urine alkalinity chloride loss.

Chlorpropamide- increase 4. Record I and O.

chlorpropamide excretion Observe for dry skin
rate R/T urine and mucous
alkalinization membranes,
polydipsia, polyuria,
Erythromycin- increase
erythromycin effect in
urine R/T increase urine
alkalinization
Ketoconazole- decrease
ketoconazole effects by
increase renal tubular
reabsorption
Tetracycline – tetracycline
effect R/T increase kidney
excretion.
and air hunger, may
indicate a reversal of
metabolic acidosis.
With acidosis, assess
for the relief of
dyspnea and hyper
apnea.
5. Consuming sodium
bicarbonate with
milk or calcium may
result in a milk-alkali
syndrome. Report
immediately if
anorexia, N and V, or
mental confusion
occurs.