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NPTEL (https://swayam.gov.in/explorer?ncCode=NPTEL) » Basic course in Biomedical Research (course)

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Unit 1 - Basic course in Biomedical Research : Cycle 2 (Mar-Jun

2020)

Course outline
Assignment 1: Introduction to health
research
Basic course in
Biomedical
Research : Cycle 2
(Mar-Jun 2020) Your last recorded submission was on 2020-03-27, 21:06 IST Due date: 2020-06-30, 23:59 IST.

Lecture 1: 1) Any systematic error in the design, conduct or analysis of a study that results in an erroneous estimate 1 point
Introduction to of an exposure's effect on the risk of disease is called:
health research
(unit? a) Confounding
unit=1&lesson=2) b) Bias
Quiz : c) Interaction
Assignment 1: d) Stratification
Introduction to
health research 2) Which of the following is not part of ethics review of a project? 1 point
(assessment?
name=55) a) Informed consent document and procedure

Lecture 2: b) Competence of researcher and institute conducting research

Formulating c) Sharing and protection of intellectual property
research question
d) Care and support during and after completion of research
(unit?
unit=1&lesson=3) 3) A study was conducted to assess the extrapyramidal side effects of a new antipsychotic drug in patients 1 point
Quiz : Assignment with schizophrenia. Many of these patients were smokers and some of them were on anticholinergic drugs. What
2: Formulating was the role of the anticholinergic drugs in this study?
research question
(assessment? a) Confounder
name=57) b) Random Variable
Lecture 3: c) Effect Modifier
Literature review d) Independent Variable
(unit?
unit=1&lesson=4)
Quiz : Assignment 4) Before initiating the study, the Principal Investigator must ensure that various approvals are obtained. 1 point
3: Literature review Which of the following approvals is/are absolutely mandatory?
(assessment?
name=61) a) Scientific committee approval
b) Ethics committee approval
Lecture 4:
Measures of c) Technical committee approval
disease frequency d) Regulatory authority approval
(unit?
unit=1&lesson=5)
All

Quiz : Assignment 5) The policy makers want to know whether introduction of a new rotavirus vaccine in the national 1 point
4: Measures of immunization programme is resulting in reduction of morbidity and mortality from rotavirus disease. Which of the
disease frequency following studies will they have to conduct to find an answer?
(assessment?
name=75) Case-control study

Lecture 5:
Ecological study
Descriptive study Field randomized trial
designs (unit?
Case-series
unit=1&lesson=6)
6) What effect does increasing the sample size have upon the random error? 1 point
Quiz : Assignment
5: Descriptive
a) It increases the random error
study designs
(assessment? b) It has no effect on the random error
name=78) c) It reduces the random error
Lecture 6: d) None of the above
Analytical study
designs (unit?
7) Which of the following will best describe the scientific inquiry that seeks to understand the acceptability 1 point
unit=1&lesson=7) and functionality of a health program?

Quiz : Assignment a) Basic science research

6: Analytical study
b) Translational research
designs
(assessment? c) Clinical research
name=77) d) Implementation research
Lecture 7: e) None of the above
Experimental study
designs: Clinical
8) The following statements describe confounding and effect modification. Which of the statement is/are 1 point
trials (unit? correct?
unit=1&lesson=8)
a) In a study of relationship between coffee drinking and oro-pharyngeal cancer; smoking is a confounder
Quiz : Assignment
b) In a study to explore relationship between hepatitis B infection and post-infection hepatic sequelae, habit
7: Experimental
of alcohol drinking acts as an effect modifier and patients with this habit may be excluded from the study
study designs
(assessment? c) 'a' and 'b' are correct
name=62) d) 'a' and 'b' are wrong
Lecture 8: Validity
9) Issues regarding shipment of samples and transfer of data outside the country are examined by: 1 point
of epidemiological
studies (unit?
a) Regulatory review
unit=1&lesson=9)
b) Ethics review
Quiz : Assignment
c) Scientific review
8: Validity of
epidemiological d) None
studies
10)Which of the following disciplines contribute to health research? 1 point
(assessment?
name=79)
a) Bio-medical research
Lecture 9: b) Biostatistics
Qualitative
c) Social science research
research methods: d) All of the above
An overview (unit?
unit=1&lesson=10) You may submit any number of times before the due date. The final submission will be considered for grading.

Quiz : Assignment Submit Answers

9: Qualitative
research methods
(assessment?
name=80)

Lecture 10:
Measurement of
study variables
(unit?
unit=1&lesson=11)

Quiz : Assignment
10: Measurement
of study variables
(assessment?
name=72)

Lecture 11:
Sampling methods
(unit?
unit=1&lesson=12)

Quiz : Assignment
11: Sampling
methods
(assessment?
name=71)

Lecture 12:
Calculating sample
size and power
(unit?
unit=1&lesson=13)

Quiz : Assignment
12: Calculating
sample size and
power
(assessment?
name=70)

Lecture 13:
Selection of study
population (unit?
unit=1&lesson=14)

Quiz : Assignment
13: Selection of
study population
(assessment?
name=76)

Lecture 14: Study

plan and project
management
(unit?
unit=1&lesson=15)

Quiz : Assignment
14: Study plan and
project
management
(assessment?
name=63)

Lecture 15:
Designing data
collection tools
(unit?
unit=1&lesson=16)

Quiz : Assignment
15: Designing data
collection tool
(assessment?
name=64)

Lecture 16:
Principles of data
collection (unit?
unit=1&lesson=17)

Quiz : Assignment
16: Principles of
data collection
(assessment?
name=65)

Lecture 17: Data

management
(unit?
unit=1&lesson=18)

Quiz : Assignment
17: Data
management
(assessment?
name=66)

Lecture 18:
Overview of data
analysis (unit?
unit=1&lesson=19)

Quiz : Assignment
18: Overview of
data analysis
(assessment?
name=74)

Lecture 19: Ethical

framework for
health research
(unit?
unit=1&lesson=20)

Quiz : Assignment
19: Ethical
framework for
health research
(assessment?
name=67)

Lecture 20:
Conducting clinical
trials (unit?
unit=1&lesson=21)
 Quiz : Assignment
20: Conducting
clinical trials
(assessment?
name=68)

Lecture 21:
Preparing a
concept paper for
research projects
(unit?
unit=1&lesson=22)

Quiz : Assignment
21: Preparing a
concept paper for
research project
(assessment?
name=73)

Lecture 22:
Elements of a
protocol for
research studies
(unit?
unit=1&lesson=23)

Quiz : Assignment
22 : Elements of a
protocol for
research studies
(assessment?
name=82)

Lecture 23:
Publication Ethics
(unit?
unit=1&lesson=47)

Quiz : Assignment
23: Publication
Ethics
(assessment?
name=69)

Text Transcripts

Cycle 1 (Sep-Dec
2019) Assignments