1. Any material intended to be used for the manufacture of a product, 28.

Advantages of plastic containers over glass EXCEPT:

whether raw materials or packaging materials: a. Lightness in weight c. Lower transportation
a. Drug product c. Component b. Permeability d. Resistance to impact
b. Batch d. Finished product 29. Advantages of glass containers EXCEPT:
2. The quantity that is actually produced at any phase of production of a a. Inertness c. Resistance to impact
particular drug based on the initial input: b. Rigidity d. Visibility
a. Theoretical yield c. Actual yield 30. Package component used to prevent damage during shipment :
b. Batch d. Lot a. Inner seal c. Coil
3. It is the instruction to the production or manufacturing department to b. Liner d. Dessicant
produce a drug for distribution: 31. Release or movement of the components of the container into the
a. MO c. SOP contents:
b. MF d. BMR a. Sorption c. Leaching
4. Any portion of a batch: b. Breathing d. Porosity
a. Lot c. Hot 32. Function of a package include:
b. Batchmate d. Material a. For convenience c. For protection of content
5. Checks and test instituted and carried out in the course of the b. For legal compliance d. All of the choices
manufacture of a drug to ensure identity, strength, quality and purity. 33. Multiple dose containers include:
a. In-process control c. Processing a. Vials c. Ampules
b. Testing d. Quarantine b. Cartridges d. Pre-filled syringe
6. The process of packing to obtain finished product 34. Function of a package include:
a. Processing c. Production a. To provide presentation c. For communication
b. Packaging d. Procedures b. To provide containment d. All of the choices
7. Articles intended to be rubbed, pored, sprinkled or otherwise applied to 35. According to the USP monograph instruction, protect from light
the human body for cleansing or beautifying: indicates storage in:
a. Cosmetics c. Excipients a. Dark place c. Light resistant container
b. Active ingredient d. Bulk product b. Flint glass d. Tight glass container
8. Raw materials used in the production: 36. To protect the contents of a bottle from the action of light is to use:
a. Packaging materials c. Components a. Flint glass d. Amber colored glass
b. Starting materials d. Additives b. Green colored glass e. Plastic coated glass
9. Description of the operations to be executed: c. Colorless glass
a. Processing c. Production 37. It refers to the binding of drug molecules to the polymer material of the
b. Procedures d. Packaging plastic container:
10. All substances whether active or excipients that are employed in the a. Sorption c. Adsorption
processing of a finished product: b. Absorption d. Leaching
a. Raw materials c. Components 38. Products that are prone to decomposition by moisture generally are

m
b. Packaging materials d. Bulk product packed with a:

er as
11. Any substance of a drug, which is intended to furnish pharmacological a. Tight container c. Absorbent cotton
activity or other effect in the diagnosis, cure, mitigation, treatment or b. Vacuum seal d. Desiccant packet

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prevention of a disease or to affect any structure of function of the body: 39. Types of glass used for buffered aqueous solution with pH below 7.0

12.
a.
b.
Inactive ingredient
Drug excipient
eH w c. Active ingredient
d. Drug adjuvant
It refers to any distinctive combination of letters and/or numbers or 40.
a.
b.
Type I glass
Type II glass
c. Type III glass
d. NP
All of the following glass types may be subjected to the Powdered Glass

o.
both, by which the complete history of the manufacture, control, Test EXCEPT:
rs e
packaging and distribution of a batch of drug is determined: a. Highly resistant borosilicate glass
a. Drug Registration Number c. Manufacturing Order Number b. Treated soda-lime glass
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b. Batch number d. Finishing Order Number c. Soda-lime glass

13. A wavy condition of horizontal lines in the body of the bottle: d. General purpose soda lime glass
a. Washboard c. Seeds 41. Factors that accelerate instability include
b. Hard blister d. Tear a. Temperature c. Moisture
14. A sunken center portion at the bottom of the bottle: b. Light d. All of the choices
o

a. Soft blister c. Rocker bottom 42. Type of container that protects the content from extraneous solids,
b. Freaks d. Poor distribution liquids, or vapors from loss of the drug:
aC s

15. Hair like string inside the bottle: a. Hermetic c. Tight

a. Filament c. Check b. Well-closed d. Light resistant
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b. Overpress d. Split 43. Highly resistant borosilicate glass is also known as:
16. Odd shapes and conditions that render the container completely a. Type I c. Type III
unusable: b. Type II d. NP
a. Freaks c. Stone 44. To assign in assuring the stability of a dosage form during transport and
y

b. Cracks d. Splits storage, the label shall indicate:

17. Small inclusion of any non-glass material: a. Storage condition c. Concentration of the drug
ed d

a. Mismatch c. Pinhole b. Expiry date d. All of the choices

b. Fin d. Stone 45. According to USP standard, freezer or refrigerator can be used to store
ar stu

18. Partial fractures generally found in the hell area, but sometimes pharmaceuticals that specify storage in a :
occurring at the shoulder: a. Cool place c. Controlled room temperature
a. Soft blister c. Stone b. Cold place d. Dark place
b. Cracks d. Mismatch 46. The temperature of a cool place is:
19. Critical defect in glass containers: a. Not more than 8ºC c. 15-30ºC
a. Chocked bore c. Tear b. 8-15ºC d. 25ºC
is

b. Stone d. Hard blister 47. The usual storage condition specified for biologicals is:
20. Major defect in glass containers: a. Room temperature c. 2-8ºC
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a. Chipped finish c. Overpress b. Below 2ºC d. Cool place

b. Suncker shoulder d. Washboard 48. The prominently printed element on the label:
21. Minor defect in glass containers: a. Brand name c. Pharmacologic category
a. Washboard c. Spike b. Rx symbol d. Generic name
b. Rocker bottom d. Poor distribution 49. In labelling of a product, an unlabelled portion is provided for:
22. Broad classification of glass defects include: a. Viewing the contents d. Art design
sh

a. Checks c. Non-glass inclusion b. Elegance e. Saving of glue applied

b. Marks d. All of the choices c. Save cost of label
23. Primary package systems as differentiated from secondary package 50. Substance that “glue” powder together causing them to form granules:
systems: a. Diluent c. Lubricant
a. Are in direct contact with the product b. Binder d. Disintegrant
b. Have a direct effect on product shelf life 51. An agent that acts between surfaces in relative motion to prevent
c. All of the above friction and wear
d. None of the above a. Diluent c. Lubricant
24. The only true tamper resistant packaging: b. Binder d. Disintegrant
a. Aerosol containers c. Breakable caps 52. Which of the following is not classified as a lubricant?
b. Sealed tubes d. Shrink seals a. Lactose c. Ca Stearate
25. The container of choice for parenterals: b. Stearic acid d. Talc
a. Plastic c. Metals 53. Spans & Tweens are:
b. Glass d. Tubes a. Binders c. Preservatives
26. The container of choice for ointments: b. Diluents d. Surfactants
a. Jars c. Collapsible tubes 54. Use of buffers in parenterals:
b. Cans d. Widemouth bottle a. pH stabilizer c. Tonicity contributor
27. Primary packaging components EXCEPT: b. Sterilizer d. A and C
a. Labels d. Caps 55. The following are preservatives used in dosage forms EXCEPT:
b. Bottles e. Stoppers a. Cellulose c. Methylparaben
c. Tubes b. Propylparaben d. Na benzoate

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 56. Buffers are used: d. Initial dry mixing → Wet mixing → Drying → Dry screening →
a. To bring about the solubility of insoluble substance. Final dry mixing → Compression
b. To maintain the pH of the solution thus attaining maximum 81. If too much Granulating liquid added in wet mixing of powders will
stability. result to these following EXCEPT:
c. As preservative a. Overwetting
d. None of the above b. Too hard granules
57. Materials added to provide cohesion in components for compression: c. Increase in drying time
a. Lubricant c. Fillers d. Break back into powders
b. Binder d. Disintegrant 82. If lesser Granulating liquid added in wet mixing of powders will result to
58. Starch, Povidone, Mg Stearate, and Lactose added to Aspirin tablets are: these following EXCEPT:
a. Actives c. Vehicles a. Underwetting
b. Inerts d. Additives b. Too hard granules
59. The following are Binders, EXCEPT: c. Difficulty in forming tablets
a. Starch c. Bentonite d. Break back into powders
b. Acacia d. Cab-O-sil 83. All of the following are QC TEST for Tablet EXCEPT:
60. One of the following substances is not used as lubricant in tablet a. Dissolution test c. Bloom strength
manufacture: b. Dosage form uniformity test d. Identity test
a. Starch c. Mg stearate 84. Drug that relieves pain:
b. Talc d. Ca Stearate a. Analgesic c. Thrombolytic
61. An adjunct necessity for oral liquids to prevent bacterial contamination: b. Antipyretic d. None of the above
a. Antioxidants c. Preservatives 85. Drug that reduces fever:
b. pH stabilizers d. Buffers a. Analgesic c. Thrombolytic
62. A broad-spectrum preservative effective against bacteria and molds; b. Antipyretic d. None of the above
a. Parabens c. Sodium benzoate 86. The process of reducing substances to fine particles by rubbing them in
b. Alcohol d. Glycerin a mortar with pestle:
63. Substances of varying densities, which make up the major portion of the a. Trituration c. Levigation
tablet, making the compression cycle possible: b. Pulverization by intervention d. Fusion
a. Disintegrants c. Glidants 87. What is the use of Starch in Aspirin tablet formulation:
b. Bulking agents d. Granulating agents a. Preservative c. Diluent
64. Colorants are added to formulation for: b. Binder d. Lubricant
a. Meeting FDA requirements 88. The method for the preparation of compressed tablets wherein the
b. Trying which of them is suitable for the product granulation is formed by compacting large masses of the mixture and
c. Satisfying the request of marketing department subsequently crushing and sizing these pieces into smaller granules.
d. Research during manufacturing a. Dry granulation method c. Direct compression method
e. Aesthetic purpose b. Wet granulation method d. All of the above
65. Materials which help the tablet break up and dissolve to release the 89. A method of preparation of tablets whose components are sensitive to
medicament are called: moisture and elevated temperatures during drying, yet possess inherent
a. Anti-adherents c. Disintegrants cohesive properties:

m
b. Solubilizing agents d. Diluents a. Dry granulation method c. Direct compression method

er as
66. Excipient used to prevent the drying of preparations, particularly b. Wet granulation method d. All of the above
ointments and creams is called: 90. Granulation of choice for Aspirin tablet?

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a. Humectant c. Plasticizer a. Dry granulation method c. Direct compression method

67.
b. Vehicle eH w
d. Solvent
An agent that acts between surfaces in relative motion to prevent
friction and wear.
b. Wet granulation method d. All of the above
91. Which of the following is a common brand name of Aspirin tablet?
a. Aspilet c. Pirinas

o.
a. Diluent c. Disintegrant b. Espeleta d. Esperin
rs e
b. Binder d. Lubricant 92. Which of the following is not a pharmacological and therapeutic use of
68. Solid containing unit dose of one or more medicament that is prepared Aspirin
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by mould method or compression method: a. Thrombolytic d. Antipyretic

a. Tablet c. Lotion b. Analgesic e. None of the choices
b. Capsule d. Liniment c. Anti-inflammatory
69. Most common oral solid dosage form: 93. A medication in a gelatin container that has a primary advantage of
a. Tablet c. Lotion masking unpleasant taste of its contents.
o

b. Capsule d. Liniment a. Tablet c. Lotion

70. Common excipients for tablet include: b. Capsule d. Liniment
aC s

a. Lubricants d. Disintegrants 94. Capsules that are normally used for dry powdered ingredients:
b. Glidants e. All of the choices a. Hard-gelatin capsule c. Dry-filled capsule
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c. Binders b. Soft-gelatin capsule d. A & C

71. The following are common brand names of Paracetamol tablet EXCEPT: 95. Capsules that are primarily used for oils and for active ingredients that
a. Biogesic c. Dolfenal are dissolved or suspended in oil:
b. Tylenol d. Tempra a. Hard-gelatin capsule c. Dry-filled capsule
y

72. What is the use of parabens in the Paracetamol tablet formulation? b. Soft-gelatin capsule d. A & C
a. Preservative c. Diluent 96. What is the use of starch in Aspirin capsule formulation:
ed d

b. Binder d. Lubricant a. Preservative c. Diluent

73. What is the use of Mg stearate in the Paracetamol tablet formulation? b. Binder d. Lubricant
ar stu

a. Preservative c. Diluent 97. Which of the following is a specially designed capsule?

b. Binder d. Lubricant a. Spansule d. Kapseal
74. What is the use of starch in the Paracetamol tablet formulation? b. Pulvule e. All of the choices
a. Preservative c. Diluent c. Kapseal
b. Binder d. Lubricant 98. Capsule shell usually composed of:
75. What is the use of gelatin solution in the Paracetamol tablet a. Gelatin c. Colorants
is

formulation? b. Water d. All of the choices

a. Preservative c. Glidant 99. Partial hydrolysis of collagen from animals:
Th

b. Binder d. Lubricant a. Gelatin c. Glycol

76. What is the use of talc in the Paracetamol tablet formulation? b. Glycerin d. All of the choices
a. Preservative c. Glidant 100. A 600L paracetamol drops was manufactured. If it is packed in 60-mL
b. Binder d. Lubricant bottle, the theoretical yield is:
77. Granulation of choice for Paracetamol tablet formulation? a. 100 c. 10000
a. Wet Granulation c. Direct compression b. 1000 d. 5000
sh

b. Dry Granulation d. Slugging

78. The most widely used method of tablet granulation preparation, due to
the greater probability that the granulation will meet all the physical
requirements for the compression of good tablets:
a. Wet granulation method c. Direct Compression method
b. Dry granulation method d. Fluid bed granulation
79. Which of the following statements is TRUE in using glidants, anti-
adherents and lubricants in tablet granulation?
a. Oppose the efficiency of the binder and the physical forces that act
under compression
b. Cause the adhesion of powder to form granules
c. Causes a compressed tablet to break apart when placed in an
aqueous medium
d. Reduce inter-particulate friction, thereby improving the rate of
flow of granulation
80. Which of the following sequence in tablet manufacture correctly
illustrates wet granulation method of manufacturing tablets?
a. Initial dry mixing → Wet mixing → Wet screening → Drying →
Slugging → Granulation → Final dry mixing → Compression
b. Initial dry mixing → Wet mixing → Wet screening → Drying →
Final dry mixing → Compression
c. Initial dry mixing → Wet mixing → Wet screening → Drying → Dry
screening → Final dry mixing → Compression

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