Student’s name: Valerie Valerio date: 04/19/2021 pd:1

Rheumatoid Factor
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TEAMS do the work.
https://www.youtube.com/watch?v=EB5zxdAQGzU

1. Define arthritis: painful inflammation and stiffness of the joints.

2. Explain what is rheumatoid arthritis.

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A chronic inflammatory disorder affecting many joints, including those in the hands

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and feet.

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3. List the areas of the body does the arthritis impact.
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Hands, wrists, feet, knees, ankles, shoulders and elbows can be affected.
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4. Name the signs and symptoms of rheumatoid arthritis.

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Pain or aching in more than one joint.

Stiffness in more than one joint.
Tenderness and swelling in more than one joint.
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The same symptoms on both sides of the body (such as in both hands or both knees)
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Weight loss.
Fever.
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Fatigue or tiredness.
Weakness.
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Name the tests that are used to diagnose the disease.

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  Biopsy. A biopsy helps a doctor diagnose a medical condition. ...
 Colonoscopy. During a colonoscopy, a tube is inserted into the anus to view the
inside of the large bowel. ...
 CT scan. ...
 CT scans and radiation exposure in children and young people. ...
 Electrocardiogram (ECG) ...
 Electroencephalogram (EEG) ...
 Gastroscopy. ...
 Eye tests.

5. . Explain the function of the rheumatoid factor

are proteins produced by the immune system. Normally, the immune system attacks

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disease-causing substances like viruses and bacteria

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6. Explain the role of anti-CCP and Anti-CRP and how is it used in the diagnosis of
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rheumatoid factor.
A CCP antibody test is used to help diagnose rheumatoid arthritis. It's often done
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along with or after a rheumatoid factor (RF) test. Rheumatoid factors are another
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type of autoantibody. RF tests used to be the main test to help diagnose rheumatoid
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arthritis.
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7. For each scenario below indicate if the patient is positive or negative for rheumatoid
arthritis or not.
Patient #1= Anti-CCP= negative
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RF= positive
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Patient #2= Anti-CCP negative

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RF= negative

8. Explain the function of the synovial fluid in the joints.

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 Synovial fluid, also called synovia, is a viscous, non-Newtonian fluid found in the
cavities of synovial joints. With its egg white–like consistency, the
principal role of synovial fluid is to reduce friction between the articular cartilage
of synovial joints during movement.

9. Explain what is citrullination and how is this process connected to rheumatoid

factor.
Citrullination or deimination of proteins is the reaction for converting the amino
acid arginine into the amino acid citrulline. This reaction is catalyzed by enzymes
called peptidylarginine deiminases

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This study source was downloaded by 100000792114278 from CourseHero.com on 11-27-2021 23:11:17 GMT -06:00

https://www.coursehero.com/file/89366145/Rheumatoid-Factor-Review-Handout-valeriedocx/
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