End of Unit Test

SB5 Higher

Name Class Date

1 Ebola is a communicable disease that causes fever and internal bleeding.

Which type of pathogen causes Ebola? Tick one box.
 A bacterium

 B virus

 C fungus

 D protist
(1)
(Total for Question 1 = 1 mark)
1 Obesity is a lifestyle factor that correlates with heart disease (an example of a
cardiovascular disease).
One way of measuring obesity uses body mass index (BMI). The equation for calculating
adult BMI is:
mass (kg)
2
BMI = (height (m))
a A man has a mass of 105 kg and a height of 1.84 m. Calculate his BMI. Show your
working.

BMI = _______________________________
(2)
b The graph shows the correlation between BMI and the risk of dying from heart
disease, compared with someone who has a BMI of 22.0.

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SB5 Higher

Use the graph to identify the risk of dying from heart disease for the BMI that you
calculated in part a.
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(1)

c Describe the correlation between BMI and heart disease shown in the chart.
___________________________________________________________________________________

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(1)
d The man in part a has been advised to exercise and eat more healthily. Explain this
advice.
___________________________________________________________________________________

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(2)
e A heart bypass operation is carried out on people with heart disease that has caused
blockage of coronary arteries (blood vessels that supply heart muscle cells). Explain
the importance of this operation.
___________________________________________________________________________________

___________________________________________________________________________________

(2)
f The table shows the results from an investigation into blood flow through the coronary
arteries of two groups of people. The control group was 10 non-smokers, while the
test group was 10 smokers.

Coronary blood flow

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SB5 Higher
(cm3/min/g)
At rest During
activity
control (non- 0.90 3.37
smoker)
smoker 0.93 2.22
i Compare the data for the control group with the data for smokers.
________________________________________________________________________________

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(2)
ii Suggest, with a reason, one impact on the health of smokers based on the activity
data.
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________________________________________________________________________________

(2)
(Total for Question 2 = 12 marks)
2 a Describe one physical barrier of plants that defends against infection.
___________________________________________________________________________________

___________________________________________________________________________________

(1)

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SB5 Higher

b A farmer notices that a crop in one field has yellow leaves and is not growing well.
Explain how the
farmer could identify if the cause was a lack of certain minerals.
___________________________________________________________________________________

(2)
(Total for Question 3 = 3 marks)
3 Antibiotics are a type of medicine.
In an investigation, students tested the effect of
different antibiotics on a culture of bacteria on
nutrient agar. The results are shown in the
diagram.
a Explain why the equipment and agar were
autoclaved before use in the investigation.
______________________________________________

______________________________________________

______________________________________________

______________________________________________
(2)
g The area of a circle is πr 2, where r is the radius. Use this to calculate the area of the
clear circle around disc C. Show your working.

area = mm2
(2)
(Total for Question 4 = 4 marks)
4 The chart shows the average amount of alcohol consumed per person per year in the UK
for 1994 to 2013.

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SB5 Higher
a Explain the correlation between amount of alcohol consumed and the risk of
developing liver disease.
___________________________________________________________________________________

___________________________________________________________________________________

(2)

h Use the graph to predict how the change in alcohol consumption may affect the
number of liver disease
patients in the UK over the next decade.
___________________________________________________________________________________

___________________________________________________________________________________

(2)
(Total for Question 5 = 4 marks)
5 People who are infected with HIV are said to have AIDS when they are also infected with
other pathogens,
such as the pathogen that causes tuberculosis.
a Explain why someone with HIV is more likely to be infected by the tuberculosis
pathogen than a person who does not have HIV.
___________________________________________________________________________________

___________________________________________________________________________________

(2)
i Give a reason for the health advice for men to use a condom with a new sex partner.
___________________________________________________________________________________

___________________________________________________________________________________

(1)
(Total for Question 6 = 3 marks)
6 The graph below shows a correlation between concentration of haemoglobin in the blood
and density of malarial parasites in the blood. Haemoglobin concentration is a measure of
the density of red blood cells.

a Explain the correlation shown in the graph.

___________________________________________________________________________________

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SB5 Higher
___________________________________________________________________________________

(2)
j One method used to try to prevent new cases of malaria is to spray surfaces and
standing water with insecticide. Explain this approach.
___________________________________________________________________________________

___________________________________________________________________________________

(2)

k Another approach is to give people medicines to kill the pathogen. New medicines are
being developed
to be more effective. Give a reason for the following stages in the development of new
medicines.
i tested on tissue cultures in the lab
________________________________________________________________________________

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(1)
iii tested on a large number of people with malaria in a clinical trial
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(1)
(Total for Question 7 = 6 marks)
7 Some viruses have two pathways in their life cycle.
Describe what happens after a virus has infected a cell during the lytic pathway of the life
cycle.
_________________________________________________________________________________________

_________________________________________________________________________________________

(2)
(Total for Question 8 = 2 marks)
8 The diagram shows how monoclonal antibodies are made.

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SB5 Higher

a Explain the use of lymphocytes and cancer cells to make hybridoma cells.
___________________________________________________________________________________

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(2)

l Monoclonal antibodies have been made that carry cell-killing drugs. Explain the
advantage of using
these monoclonal antibodies rather than the older treatment of giving the person with
cancer large amounts of cell-killing drugs.
___________________________________________________________________________________

___________________________________________________________________________________

(2)
(Total for Question 9 = 4 marks)
2 Although most children in the UK are immunised against diseases such as measles,
mumps, polio and
rubella, a few are not because they are respond badly to the vaccine. Explain how
immunisation of the majority of children protects all the children in a community from
these diseases.
_________________________________________________________________________________________

_________________________________________________________________________________________

_________________________________________________________________________________________

_________________________________________________________________________________________

_________________________________________________________________________________________

_________________________________________________________________________________________

_________________________________________________________________________________________

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SB5 Higher
_________________________________________________________________________________________

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(6)
(Total for Question 10 = 6 marks)
TOTAL FOR TEST = 45 MARKS

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