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(PDF) The Weight of A Finger-Tip Unit of Ointment in 5-Gram Tubes
(PDF) The Weight of A Finger-Tip Unit of Ointment in 5-Gram Tubes
Authors:
Itaru Dekio
The Jikei University School of Medicine
Eishin Morita
Figures
A finger-tip unit.
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LETTER
Clinic for Atopic Dermatitis, Department of Dermatology, Faculty of Medicine, Shimane University, 89-1 Enya-cho,
Izumo 693-8501, Japan
B.
*Correspondence: Itaru Dekio, Department of Dermatology, Faculty of Medicine, Shimane University , 89-1 Enya-cho, Izumo 693-8501, Japan.
Fax: +81 853 21 8317. E-mail: dekio@mx2.et.tiki.ne.jp
Weight of
Trade name Inner diameter squeezed ointment Length of Weight
(manufacturer) Ingredient of nozzle (mm) per tube (g) ointment line (cm) per FTU (g)
Antebate ointment Betamethasone butyrate 3.8 4.82 ± 0.05 46.9 ± 10.9 0.277
(Torii) propionate 0.05% (17.4 FTU)
Dermovate ointment Clobetasol propionate 0.05% 3.4 4.66 ± 0.03 50.2 ± 3.9 0.250
(GlaxoSmithKline) (18.6 FTU)
Rinderon VG ointment Betamethasone valerate 0.12% 4.2 4.75 ± 0.03 41.0 ± 1.5 0.312
(Shionogi) supplemented with (15.2 FTU)
gentamicin sulfate 0.1%
Furthermore, to determine the relationship between FTU for a 5-mm diameter nozzle is 0.49 g, that for
the diameter of nozzle and the weight of a FTU, we a 4.2-mm diameter nozzle is 0.29 g, and that for a
performed the following calculation using a scheme 3.4-mm diameter nozzle is 0.23 g. So the constant A is
shown in Figure 3 (where D = diameter of syringe- calculated by the substitution of this formula:
shaped ointment, L = length, and r = density):
0.49 = A × 52 , 0.29 = A × 4.2 2 , 0 .23 = A × 3.4 2
(section area) = π ( D/2)2 = ( π/4) D 2
A ≈ 0.02.
(volume) = L × (section area) = (π/4) LD2 In this context, the weight is easily estimated as
follows:
(weight) = ρ × ( volume ) = ( π/4) r L × D2
1 FTU (g) = A × D2 ≈ 0.02 ×
This theoretical calculation shows that the weight of a ( inner diameter of the nozzle, mm)2 .
finger-tip unit is in proportion to a square of the diam-
eter. That is to say, the relationship of the weight and the Lastly, we consider that it is appropriate to consider 1
diameter can be described in the following formula: FTU = 0.25 g (4 FTU = 1 g) but not 1 FTU = 0.5 g
(2 FTU = 1 g) when prescribing steroid ointments in
(weight of 1 FTU) = A × D 2 , 5-gram tubes (2). Moreover, the ‘rule of hand’, that
states 1 FTU of ointment covers the area of two hand-
where A is a constant defined by the concentration of prints (3), should be reconsidered when prescribing
ointment and the length of a finger-tip and D is the ointmentspackedin suchsmalltubeswith smallnozzles.
diameter of the syringe-shaped ointment (inner diam-
eter of the nozzle).
With regard to our data and the report of Finlay et al. Acknowledgement
(1), when we consider the length is fixed to 2.5 cm and
concentrations are the same in the UK and in Japan, 1 We thank Prof. Makiko Kouchi, Digital Human
ResearchCenter,NationalInstituteofAdvancedIndus-
trial Science and Technology, for providing us with his
unpublished data on the length of the distal phalanx of
the index finger of a healthy Japanese population.
D r
D/2
References
1. Finlay AY, Edwards PH, Harding KG. “Fingertip unit” in
L
dermatology. Lancet. 1989;15(8655):155.
2. Long CC, Finlay AY, Averill RW. The rule of hand: 4 hand
Figure 3. Scheme for calculation of the weight of a finger-tip unit of areas = 2 FTU = 1 g. Arch Dermatol. 1992;128:1129–1130.
ointment, where D is the diameter (i.e. the inner diameter of the 3. Kalavala M, Mills CM, Long CC, Finlay AY. The finger-tip
nozzle) of syringe-shaped ointment; L and r are length and density, unit: A practical guide to topical therapy in children.
respectively. J Dermatolog Treat. 2007;18:319–320.
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