Professional Documents
Culture Documents
Name: Proviso
Model: Specific Proteins Analyzer
Configuration: Analyzer, accessories and consumables
Intended Use: Quantitative analysis of body glucose components
WARNINGS AND PRECAUTIONS
Meril Diagnostics makes no representation that, upon furnishing this service manual, the
holder of the manual will have the necessary technical capabilities and know-how to
properly troubleshoot and repair any of the equipment specified in the manual. Meril
Diagnostics assumes no liability whatsoever, including consequential and incidental
damages, resulting from improper operation of Meril Diagnostics instruments after
maintenance of Meril Diagnostics instruments has been performed by persons not
employed by Meril Diagnostics Furthermore, Meril Diagnostics assumes no liability
whatsoever for any personal injury or property damage resulting from maintenance
and/or repair of Meril Diagnostics instruments performed by persons not employed by
Meril Diagnostics
Meril Diagnostics urges its customers to comply with all national health and safety
standards such as the use of barrier protection. This may include, but it is not limited to,
protective eyewear, gloves, and suitable laboratory attire when operating or maintaining
this or any other automated laboratory analyzer.
"This Service Manual contains confidential information of Meril Diagnostics and its
receipt or possession does not convey any rights to reproduce, disclose its contents, or
to manufacture, use, or sell anything it may describe.
Reproduction, disclosure, or use without specific written authorization of Meril
Diagnostics is strictly forbidden."
Table of Contents
S.No Content Page No
1 Inroduction
i)Scope
ii)Test terms
iii)Safety precautions
2 Technical Drawing
3 Instrument Description
i)Introduction
ii)Features
iii)Technical parameters
iv)List of Board assemblies
4 Block Diagram
5 Electrical testing
6 Gain Calibration
7 Troubleshooting
8 Error log
9 Service Menu
10 Maintainance
1. INTRODUCTION
1.1 Scope
This manual provides the reference information and procedures needed for servicing
and maintaining the Merilyzer Proviso specific proteins analyzer.
It is available in two electronic versions:
HTML - recommended for viewing because it is quicker to open and easier to navigate.
PDF - recommended for printing because it has a normal page layout and numbering.
Both versions will be included in the Service Resource Kit
Proviso is a 32 bit micro controller based Specific Proteins Analyzer, designed to meet
the demanding requirements of today’s Routine Chemistries applications, with ease of
operation and high precision results.
The Analyzer has Power ON Diagnostics check to check hardware modules during
power ON.
S.No Tests
1 ASO
2 CRP
3 HBA1C
4 RF
5 APOA1
6 APOB
7 AT_III
8 CYSC
9 C3
10 C4
11 D_DIMER
12 FER
13 HCRP
14 IgA
15 IgG
16 IgM
17 LPA
18 uALB
19 uGlobB2
20 TRSF
1.3 Safety Precautions
1.3a Special
This group of warnings concerns conditions that can affect both your immediate personal
safety and the future safety of the instrument’s operators.
WARNING: Risk of personal or operator injury. Covers and interlocks are installed
on the instruments to prevent injury from operating components. If you must
remove covers or disable interlocks to service an instrument:
1. Be alert and use extreme care when working around exposed components to avoid
personal injury.
2. At the end of the service call, always reinstall all instrument covers and ensure
interlocks are enabled to prevent operator injury.
1.3b Electronic
Bring the following warning to the customer’s attention before advising that customer to
do any service, maintenance or troubleshooting procedures on the Analyzer
.
WARNING: Risk of personal injury or contamination. If you do not properly
shield yourself while doing service, maintenance, and troubleshooting
procedures, residual fluids in the Analyzer could injure or contaminate you. Meril Life
recommends that you wear barrier protection, such as appropriate safety glasses, a lab
coat, and gloves throughout the performance of service, maintenance, and
troubleshooting procedures to avoid contact with cleaners and residual fluids in the
Analyzer.
Also, make sure customers are aware of the warning and information labels
2. Technical drawing
3.1 Introduction
Merilyzer Proviso incorporates both turbidimetric & Nephelometric testing methods and
principle of Fix-time transmission Immunoturbidimetry and fix-time immunonephelometry
method.
Turbidimetry measures the intensity of the light transmitted which is inversely
proportional to the amount of particles present in the solution.
Nephelometry directly measures the intensity of light scattered which is proportional to
the amount particles in the solution.
3.2 Features
Main board is responsible for communication between different working modules. It contains
main micro-controller LPC1769 (32 bit) which handles all the operations / activities, calculate the
results & gives output on Display / Thermal Printer or send results to PC through RS-232 serial
cable/serial to USB cable.
Power supply PCB provides regulated DC voltage supply to all electronics components,
namely:
Main Board/ Target/ Transmission-Scattering Photodiode Board Logic Supply
Laser/LED power section
Incubation and PHM Heater Driving
Thermal Printer logic and power section
DC Motor Driving
3.4.c. Target Board Assy.
Target Board has 16 Bit ADC AD7705 which receives signals from Transmission and
Scattering Board and converts it into digital signals which goes to main board micro-
controller for further signal processing and display.
3.4.e.
Scattering Board Assy.
Scattering Photodiode PCB receives scattered signal through sample cuvette and
passes it to Target/PHM Board ADC section.
3.4.f.
Thermal
Printer
Board
assy.
Thermal
printer is
used for result printouts on a thermal paper. Printer board receives power from Power
supply board and control signals from main board.
Smart Card PCB is used to fetch test parameters stored in smart card and send it to
Main Board for result calculation.
3.4.h.
Two Temperature Sensor PCBs are used for sensing Testing Block Temp and Incubator
Block temp. DS18B20 Digital Sensor IC is used for temp sensing purpose.
4. Block Diagram:
5 Electrical Testing
a. Electrical Testing
* After Power ON electrical testing confirm following*
Connect Adapter to DC Jack on Power Supply Board and connect switch assy. Check
1.
voltages at following points on Power Supply board when switch is ON.
Required Volt. Range
Test Point On Power Supply Board Assy.
Connect Adapter to DC Jack on Power Supply Board and connect switch assy also connect
2 J7(Power Supply) to J3(Printer PCB) using cable assy. Check voltages at following points on
Printer board when switch is ON.
Connect J4 (Power Supply) and J1 (Main Board) by cable assy and power ON. Check
3
voltages at following points on Main board.
Connect MB and PS board using cable assembly and Temp sensor board to J3 connector on MB
and heater with mechanical block to J2 on MB.
Observe incubation block temperature attaining to 37°C or not after 15 mins of power ON.
h) Steps to check temp:
Main Menu --> SETTINGS --> HELP -->Press Up key once,Down key
Twice,Right key once, Left key Twice -->1.Edit M/C Params --> ( screen will
display PHM Block Temp and INCUB Block Temp)
Switch OFF instrument. Connect J4 (Power Supply) and J1 (Main Board) , J1 (Target
4 Board) and J7 (Main Board), J2 (Power Supply) and J6(Target Board) by cable assy. Check
voltages at following points on Target Board.
Switch OFF instrument. Connect J4 (Power Supply) and J1 (Main Board) , J1 (Target
5 Board) and J7 (Main Board), J2 (Power Supply) and J6(Target Board), J6(Main Board) to
J1(Smart Card PCB) by cable assy. Check voltages at following points on Smart Card PCB.
Switch OFF instrument. Connect J4 (Power Supply) and J1 (Main Board) , J1 (Target
Board) and J7 (Main Board), J2 (Power Supply) and J6(Target Board), J7 (Target Board)
6
to J1(Scattering Board), J8 (Target Board) to J1(Transmission Board) by cable assy. Check
voltages at following points on Transmission and Scattering Board.
Check transmission count in air ( ie. without cuvette) and set to 60000 by varying R2 on
b)
Transmission PCB.
6.2. Scattering Channel Gain Settings:
Power ON instrument.
Go to Settings -> Counts.
Check scattering count by keeping cuvette with calibration solution.
Set Scattering Counts to 15000 by varying R2 on Scattering PCB.
6 Gain Calibration
Gain calibration is done by adjusting Gain pot on Transmission and Scatterring Board
and by setting Laser/LED voltage.
Check transmission count in air ( ie. without cuvette) and set to 61000 by varying R2
on Transmission PCB.
Sr.
Issue Cause analysis Solution
No.
12. Serial port Loose / no connection of Press/ reinsert the cable assy for the
cables. same.
communication issue Main Board is faulty. Change the main board assy.
8. Error log
9. Service Menu
Fig. 9.a
Click on "Help"
menu.
Fig. 9.b.
Fig. 9.d
Fig 9.e
Fig. 9.f
Fig. 9.g
Fig 9.h
Fig 9.i
10.0 Maintenance
Correct Incorrect
When the instrument is on, feed the printing paper to the feeder under the paper delivery roll
press paper feed, the printing paper will come out automatically.
Printer Maintenance
Take out the roller at first, pull out the print paper.
Take out the roller, clean the printer heater by using the cotton swab
Attention
The power supply voltage is AC 230V. If the power supply is insufficient please use the AC
stabilized voltage supply not less than 200W to ensure the instrument works well.
Merilyzer Proviso should be installed far from electromagnetic radiation source and high
frequency radiation device (radio telephone and wireless phone, etc)
Only the trained personnel can use Merilyzer Proviso.The manufacturer and authorized
agency should be responsible for the training.
Recommended to use Merilyzer Proviso with compatible reagent and cuvettes to ensure the
accuracy of the result.
Please remove the testing sample and reagent before the instrument is shifted to another
location.
Every Merilyzer Proviso has been inspected before packing. Please do not change the setting
and supporting facilities.
Important Notes
Avoid direct sunshine and bright light and keep away from high heat object and strong
electromagnetic interference source.
Do not touch the lower part of the cuvette to ensue the testing accuracy.
The Electronic pipette has wearing parts. Please change after 5000 times of use.
Recommended to use the touch pen for LCD operation.
Remove the cuvette from the testing position after testing and keep the testing position
vacant.
Do not touch the screen while testing .The Go back key can be pressed accidently and the
test will be incomplete .