Professional Documents
Culture Documents
A THESIS
SUBMITTED TO
KATHMANDU UNIVERSITY
IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE
DEGREE OF MASTER OF SURGERY IN ORTHOPAEDICS
(MS ORTHOPAEDICS)
DEPARTMENT OF ORTHOPAEDICS
NOBEL MEDICAL COLLEGE TEACHING HOSPITAL
NOVEMBER, 2021
DEDICATED TO
MY FAMILY
AND
i
DECLARATION
I hereby declare that I am the sole author of the work relating to this thesis entitled “SHORT
NEPAL” and that it has not been submitted for any degree previously.
I authorize the Kathmandu University to lend this thesis to other institutions or individuals
I further authorize the Kathmandu University to reproduce this thesis by any means
November, 2021
ii
ACKNOWLEDGEMENT
I take this opportunity to express my heartfelt thanks to all the people who have contributed
I am extremely grateful to my preceptor and guide Prof. Dr. Uday Chandra Chaudhary sir for
his valuable supervision, encouragement and invaluable guidance. My special thanks to Prof.
Dr. Dilip Majumdar sir for his immense support and motivation into the study of the subject.
I wish to thank to our in-charge, Associate Prof. Dr Prakash Sitoula sir, Associate Prof. Dr.
Ranjib Jha sir and Asst.Prof. Dr.santosh Thapa sir of our Department of Orthopaedics for
their continued advice and support. I also like to express my gratitude to our lecturers- Dr.
Sandip Adhikari, Dr. Dhiraj Singh, Dr. Suman Dhoj Kunwar, Dr. Bishamber Thapa, Dr.
Aashish Rajthala, Dr. Bikal Gautam and Dr. Lalit Kumar Bohra for their wonderful guidance.
I would also like to thank very helpful physiotherapist Dr. Pramod Kumar Mehta. I am also
staffs and staffs at the orthopaedic ward.My special thanks to Mr. D.D. Baral for lending me
I would like to thank my parents for making me able to serve the needy. I would also like to
Finally, I would like to thank all my patients who have contributed a lot for the completion of
this thesis.
November, 2021
iii
CERTIFICATE BY THE PRECEPTOR
This is to certify that this thesis entitled “SHORT TERM ANALYSIS OF FUNCTIONAL
CENTRE OF EASTERN NEPAL” is a good research work by Dr. Suraj Shahi under my
supervision and guidance in partial fulfillment of the requirement for the degree of Master of
I further affirm that this research project has been duly approved and ethically cleared by the
Institutional Review Committee of Nobel Medical College Teaching Hospital. The data
────────────────
Professor
Department of Orthopaedics
November, 2021
iv
CERTIFICATE OF ETHICAL CLEARANCE
v
GLOSSARY OF ABBREVIATION
AP Antero-Posterior
IP In Patient
CI Confidence Interval
ABSTRACT
medical complications in these fractures, early mobilization is needed. There are many
methods of treatment but the ideal method should be less invasive with stable fixation of
vi
facture. Proximal Femoral Nail Antirotation (PFNA) is biomechanically considered one of
the most effective methods of treatment with promising results. Aims and objectives: To
evaluate the clinical and radiological outcomes in patient who were treated with PFNA in
samples, conducted in Nobel Medical College Teaching Hospital, Biratnagar Nepal from
January 2020 to June 2021. All the samples were clinically evaluated along with obtained
detail history and after the anesthesia clearance the sample were operated. During operative
and complication were noted and in the final follow up Harris Hip Score was used for
assessing functional outcome. Result: The mean age of the sample in this study was 72 years
(55-90 years) . The average time to complete the surgery was 62.6 minutes (minimum 32
minutes- maximum 97 minutes). Fracture union was seen at the average of 13.0 weeks (12-
116 weeks). the mean Harris Hip score at final follow up was 82.4 (70-90) with functional
status of 10% excellent result , 76.7% good and 13.3% fair. Conclusion: Proximal Femoral
procedure reduces the operative time and radiation exposure .Since this is minimally invasive
procedure the blood loss is very less in compared to DHS or plate fixation. The patient can
TABLE OF CONTENTS
DEDICATED TO................................................................................................i
DECLARATION................................................................................................ii
vii
ACKNOWLEDGEMENT................................................................................iii
GLOSSARY OF ABBREVIATIONS..............................................................vi
ABSTRACT......................................................................................................vii
TABLE OF CONTENTS................................................................................viii
LIST OF TABLES.............................................................................................ix
LIST OF FIGURES............................................................................................x
INTRODUCTION..............................................................................................1
REVIEW OF LITERATURE..........................................................................20
OBJECTIVES...................................................................................................26
METHODOLOGY...........................................................................................27
RESULT............................................................................................................32
DISCUSSION....................................................................................................40
CONCLUSION.................................................................................................43
REFERENCES.................................................................................................44
APPENDIX……………………………………………………………………55
LIST OF TABLES
viii
Table 3: Distribution of patients according to side of injury ………………………………..35
ix
LIST OF FIGURES
Figure 6: AO classification…………………………………………………………………..13
x
INTRODUCTION
Background
In elderly, Intertrochanteric fracture is one of the most devastating injuries. The incidence of
these fractures increases with advancing age.[1] These patients are more limited to home
ambulation and are dependent in basic and instrumental activities of daily living. 50 % of
fracture around hip patients in elderly is of trochanteric fracture and these 50 % of fracture are
unstable type of trochanteric fractures. They are usually complicated with associated co-
morbidities like osteoporosis, diabetes, hypertension, renal failure. In such circumstances, non-
operative treatment is mainly reserved for poor medical candidates and non-ambulant patients
with minimal discomfort after fracture. Today operative treatment has largely replaced
conservative measures and the goal of treatment is to achieve accurate or acceptable. anatomical
and stable reduction with rigid internal fixation .in order to achieve early mobilization of
implant design, surgical technique and patient care, intertrochanteric fractures continue to
consume a substantial proportion of our health care resources and remain a challenge to
date[2,3,4].
The intertrochanteric region of the hip consisting of the area between the greater and
lesser trochanters represent a zone of transition from femoral neck to the femoral shaft. This
area is characterized primarily by dense trabecular bone that serves to transmit and distribute
stress similar to the cancellous bone of the femoral neck. The greater and lesser trochanters
are the sites of insertion of the major muscles of the gluteal region, the gluteus medius and
minimus, the iliopsoas and short external rotators. The Calcar femorale, a vertical wall of
1
dense bone extending from the posteromedial aspect of the femoral shaft to the posterior
portion of the femoral neck forms an internal trabecular strut within the inferior portion of
the femoral neck and intertrochanteric region which acts as a strong conduit for stress
transfer.5,6,7,8,9
The musculature of the hip region can be grouped according to function and location.
The abductors of the gluteal region, gluteus medius and minimus which originate from the
outer table of the ilium and insert on to the greater trochanter function to control pelvic tilt in
the frontal plane. The gluteus medius and minimus along with tensor fascia latae are also the
internal rotators of the hip. The hip flexors are located in the anterior aspect of the thigh
include the sartorius, pectineus, iliopsoas and rectus femoris. Iliopsoas inserts on the lesser
trochanter. Gracilis and the adductor muscles(longus, brevis and magnus) are located in the
2
medial aspect of the thigh. The short external rotators, the piriformis, obturator internus.
Obturator externus, superior and inferior gemelli and quadratus femoris all insert to the
posterior aspect of the greater trochanter. The gluteus maximus originating from the ilium,
sacrum and coccyx inserts onto the gluteal tuberosity along the linea aspera in the
INTERTROCHANTERIC LINE: It marks the junction of anterior surface of the neck with
shaft of femur. It begins above at the anterosuperior angle of the greater trochanter and is
continuous below with the spiral line in front of the lesser trochanter. 10 It provides attachment
to the capsular ligament of the hip joint, the upper band of illiofemoral ligament in the upper
part and the lower band of iliofemoral ligament in lower part; origin to the highest fibres of the
vastus lateralis from the upper end and the origin to the highest fibres of vastus medialis from
3
INTERTROCHANTERIC CREST: This marks the junction of posterior part of neck with
shaft of femur. It begins above at the posterosuperior angle of greater trochanter and ends at
the lesser trochanter. The rounded elevation, a little above its middle is called the quadrate
tubercle, which provides insertion to quadratusfemoris extending to the area below it.10
TRABECULAR PATTERN: Ward first described the internal trabecular structure of proximal
femur in 1838. According to the wolf’s law, trabeculae are oriented along the line of stress and
thicker lines come from the calcar and raise superiorly into the weight bearing dome of the
femoral head. Upper end of femur is composed of cancellous bone which shows two different
types of trabeculae, namely the compression and tensile group.8,9The trabeculae6 have been
divided into following five groups: Primary compressive, Secondary compressive, Greater
Ward’s triangle is bounded by primary compressive, secondary compressive and primary tensile
group. Harty and Griffin described the calcar femorale a dense vertical plate of bone extending
from the posteromedial portion of the femoral shaft under the lesser trochanter and radiating
4
Figure 3 : Trabecular Pattern
5
Calcar femorale is a vertical plate of bone that extends from the posteromedial cortex of femur
deep to the lesser trochanter and blends with the posterior cortex of the femoral neck. The calcar
Epidemiology
Hip fractures are an important health-care concern in the elderly population. Currently, hip
fractures affect 18% of women and 6% of men globally with intertrochantertic fracture in ratio
female : male = 2:1 to 8:1.11,12According to Yang et.al, half of the hip fractures are
intertrochanteric.13 Epidemiological studies have demon- strated that the incidence of hip
It is also important to recognize that hip fractures confer significant social and personal
economic burden. Although hip fractures represent only 14% of all fragility fractures, these
demonstrated that apart from initial hospitalization, the cost increases much more due to
increasing need for additional care and super- vision following surgical treatment with a
proportion of patients with hip requiring long-term care.17-19 Thus, the management of hip
MECHANISM OF INJURY
Intertrochanteric fractures in young adults are the results of high energy trauma like road traffic
accidents or fall from height. In contrast, 90 % of fractures occurring in the elderly are due to a
simple fall. The tendency to fall increases with age and is exacerbated by several factors like
poor vision, altered blood pressure, poor reflexes, decreased muscle power, vascular disease and
6
coexisting musculoskeletal pathology.20 Cummings and Nevitt identified four factors that
a. The fall must be oriented that the person lands on or near the hip
c. Deficient local shock absorbers (muscle and bone around the hip)
The forces acting on the hip joint may be static or dynamic. Static force means application of
external loads or forces in such a way that they are. balanced out each other and the joint is not
subjected to acceleration.22 Dynamic forces on the other hand refer to unbalanced loads or forces
associated with acceleration / deceleration. The forces include both gravity as well as forces
generated by muscle activity. The forces acting on the hip joint result from stabilizing the body’s
centre of gravity during stance and locomotion. The centre of gravity of the body is located just
anterior to the second sacral vertebra. The horizontal distance from the centre of gravity of the
body to the centre of hip joint is 8.5 to 10 cm. vertically the centre of gravity is about 3cm above
the hip joint axis and during stance the centre of gravity is the same frontal plane as the common
hip joint axis. The force acting on the hip joint is the sum of the supported body weight and
tension developed in the abductors. The forces acting on the hip joint are normally quite large
and much more than body weight. Loss of one pound of body weight relieves three pounds of
pressure. A long femoral neck is an advantage to hip motion. The ratio of the two lever arms is
important in the generation of total force acting on the hip joint. The shorter the horizontal
distance from the centre of gravity of the body to the hip joint, less muscle force is required of
7
abductors to balance it. Medial displacement of femoral head upon the pelvis may cause a
greater decrease in joint pressure. If the individual leans the trunk directly over the weight
bearing hip, the medial lever arm is reduced to zero so that no muscle force is necessary in the
abductor tensor muscles (as in trendelenberg’s gait) joint reaction force is reduced to body
weight. If the centre of gravity is moved away from the weight bearing hip abductor force is
Operative treatment of intertrochanteric hip fractures with internal fixation creates a fracture
fragment – implant assembly intended to withstand the forces acting on the fracture site. Since
avoiding recumbency is often the goal of internal fixation and since many patients with
trochanteric hip fractures lack the balance, coordination and ability to avoid weight bearing upon
the fractured femur, it is often necessary that the fracture fragment implant assembly be strong
enough to withstand the body weight and the very considerable muscle forces which act on the
trochanteric region of femur. These forces have been shown to be equivalent to as much as three
times the body weight acting upon the femoral head. Creating a fracture fragment implant
assembly capable of withstanding loads of this magnitude is the bio mechanical goal of the
FRAGMENT GEOMETRY: Much clinical attention is focussed upon the number, location
fragment the posterior and medial portion of the trochanteric region is recognized as a major
extending into the medial and posterior femoral cortex is far more therefore likely to displace
into considered unstable, while two parts varus and retroversion. Fractures with posterior and
8
medial cortical comminution are trochanteric fractures are far more likely to be stable.
Although reduction and inter. fragmentary fixation of the lesser fragment of a comminuted
unstable intertrochanteric .fractures can contribute to the stability of the post fixation assembly,
generally agreed that one should ignore the lesser fragments and concentrate on gaining stable
fixation of the major proximal fragment to the major distal fragment attaining posteromedial
cortical contact.25
Fractures may be undisplaced or impacted and, such patients may present with minimal pain at
the hip or may present with thigh pain. They may be ambulant. Whereas patients with displaced
fractures are clearly symptomatic usually cannot stand and are non ambulant.The pain is
localized to the proximal thigh and is exacerbated by passive or active attempts of hip flexion or
rotation.Pain with motion or crepitance testing is not performed unless there are no physical
signs of deformity,and radiological studies are negative for an obvious fracture.Pain with axial
load on the hip has a high correlation with occult fracture. Because of the pain and instability,
Patients with undisplaced fracture may present with virtual absence of clinical deformity
whereas those with displaced fracture exhibit the classical presentation of shortened and
externally rotated extremity. There may be tenderness on palpation in the area of the greater
9
RADIOGRAPHIC AND OTHER IMAGING STUDIES
Standard radiographic examination includes AP view of the Pelvis, Intra-op AP and cross table
lateral view of the proximal femur. The lateral radiograph can help to assess the posterior
comminution of the proximal femur .in needed cases. An internal rotation view of the injured
hip may be helpful to identify undisplaced fractures. Internally rotating the involved femur 10 to
15 deg offsets the anteversion of the femoral neck and provides a true AP view of the proximal
femur a second AP view of the contra lateral side can be useful for preoperative planning.
Additionally, a physician-assisted AP traction view of the injured hip can be helpful in further
reduction techniques.27-29
CLASSIFICATION
Few classifications have focussed on stability and anatomical pattern (Evans; Ramadier;
Decoulx; & Lavarde) while others on maintaining reduction of various types (Jensen's
modification of Evan's, Ender; Tronzo, AO). The commonly used classification is the Boyd and
Griffin classification.30 His classification included all fractures from the extracapsular part of
Type 1: Fractures that extend along the. intertrochanteric line from the greater to the lesser
trochanter. Reduction is usually simple and is maintained with little difficulty. Results are
generally satisfactory.
Type 2: Comminuted fractures, the main. fracture being along the Intertrochanteric line but with
multiple fractures in the cortex. Reduction of these fracture are more difficult because the
10
comminution can vary from slight to extreme. A particularly deceptive form of the fracture is
one wherein there is an anteroposterior linear Intertrochanteric fracture occurs as in type 1 but
Type 3: Fractures that are basically subtrochanteric with at least one fracture passing across the
proximal end of the shaft just distal to (or) at the lesser trochanter. Varying degrees of
comminution are associated. These fractures are usually more difficult to reduce and result in
Type 4 : Fractures of the trochanteric region and the proximal shaft, with fracture in at least two
planes, one of which usually in the sagital plane and maybe difficult to see in the routine
anteroposterior roentgenograms. If open reduction and internal fixation are used two plane
fixation is required because of the spiral, oblique or butterfly fracture of the shaft.
11
Figure 4 : Boyd and Griffin Classification
Evans devised a widely used classification system based on the division of fractures into stable
and unstable groups. He divided the unstable fractures further into those in which stability could
be restored by anatomical or near anatomical reduction and those in which anatomical reduction
would not create stability.31 In Evans type 1 fracture, the fracture line extends upwards and
outwards from the lesser trochanter, in type 2, the reverse obliquity fracture, the major fracture
line extends outward and downward from the lesser trochanter. Type 2 fractures have a tendency
towards medial displacement of the femoral shaft because of the pull of adductor muscles.
12
In Orthopaedic Trauma Association. classification, Group 1 fractures are simple 2 part fractures,
group 2 fractures are comminuted with a posteromedial fragment the lateral cortex of the greater
trochanter however remains intact. Group Three fractures are those in which the fracture line
extends .across both the medial and lateral cortices. This group includes the reverse obliquity
pattern.32
31-A1.1Along intertrochanteric line 31-A1.2 Through greater trochanter 31-A1.3 Below lesser
trochanter
13
Figure 6: AO Classification
14
Treatment
There is a wide variety of treatment options for these fractures. The main goal of hip fracture
improves long-term mortality rate. In turn, surgical treatment is generally indicated unless the
The types of implant used in these fractures have been divided into extramedullary implants and
intramedullary nails. The choice of implant is mainly determined by the fracture pattern (stable
or unstable). Unstable intertrochanteric fractures are those with major disruption of the
posteromedial cortex because of comminution or are fractures with reverse oblique patterns or
The sliding hip screw device has been used for more than a decade for the treatment of these
stabilization that is especially important in the setting of unstable intertrochanteric frac- tures37.
In these situations, the lack of contact between the posteromedial osseous fragments would
result in transfer of greater medial compressive loads to the implant. 38 The intra- medullary
device is closer to the force vector line of action through the center of the femoral head and has
a shorter lever arm. Thus for the same force, the nail experiences less moment and can resist
A biomechanical study found that use of the cephalomedullary device resulted significantly less
15
fracture displacement and similar load to failure compared to sliding hip in the setting of stable
and unstable intertrochanteric fracture models.37 Results from prospective randomized controlled
trials also suggest that intra- medullary fixation was associated with superior radiographic
outcomes (limb shortening or femoral neck shortening) post- operatively and lower rates of
fractures.39,40
The presence of lateral wall fracture in reverse obliquity and transtrochanteric patterns may also
compromise the stability of an intertrochanteric fracture and thus may require intramedullary
fixation.41 Studies evaluating sliding hip screws and intra- medullary constructs found that the
presence of lateral cortical wall fracture was a significant independent predictor of implant and
treatment failure when using sliding hip screws.42,43 From a biomechanical perspective, the
lateral cortical wall acts as a lateral buttress, and thus in the presence of lateral wall fracture,
placement of a sliding hip screw can result in loss of reduction via medialization of the femoral
shaft and lateralization of the proximal femoral component.41,44 Moreover, for reverse obli- quity
fractures, the fracture plane is nearly parallel to the direction of the sliding lag screw, and thus
use of this implant will result in loss of reduction with significant collapse of the femoral
fractures, sliding hip screws were associated with higher failure rates compared to the 95○ blade
plate. However, intramedullary fixation was asso- ciated with lower rate of failure rates
compared to the 95○ blade plate.44,45 In turn, intramedullary nails are superior to sliding hip
screws for the treatment of reverse obliquity and transtrochanteric fracture or any
intertrochanteric fracture with associ- ated lateral wall fracture. This is because the
intramedullary device acts as a substitute lateral wall that can prevent medialization of the
16
femoral shaft and lateralization of the proximal femoral component.38,44 The most common
mechanism of failure of the sliding hip screw fixation is varus collapse of the femoral neck,
PFNA-II : In 2008 PFNA2 was introduced mainly to avoid lateral cortex impingement during
nail insertion which was a common problem in asian population due to shorter and narrower
greater trochanter.
PFNA-II helps in early post operative mobilization, weight bearing and ultimately the early
fracture union. PFNA-II utilizes a helical blade instead of the conventionally used two screws.
The helical blade is believed to provide stability, compression as well as rotational control of the
fracture. Theoretically it compacts the bone during insertion into the neck and hence has higher
cut out strength as compared to other devices. The differences are that mediolateral angle is
reduced from 6 degrees to 5 degrees. Lateral surface is flat and proximal nail diameter is
reduced from !7 to 16.5 mm. These changes avoided intra-operative fractures, post-operative hip
pain, allowed easier insertion, specifically for Asian population and there is less chance of
modification of the conventional PFN which reduces even the minimal complications associated
PFN has some demerits like implant failure, screw cut out and screw migration which is also
called z effect. In this Z effect proximal screw (de-rotation screw) of PFN migrate medially and
distal screws (lag screw) migrate backward, while in reverse Z effect proximal screw (derotation
screw) migrate laterally and distal (lag screw) migrate medially. 50 Intramedullary nailing has
17
advantage of short incision, less operative time, rapid rehabilition and thus decreased medical
strength in osteoporotic bones. Biomechanical studies has demonstrated that PFNA II blade has
a significance of higher cut out resistance than other commonly used screw systems.51
Several clinical and biomechanical studies have analysed the results of different implants such
as the dynamic hip screw (DHS)/Sliding / , the Gamma nail (GN) and the proximal femoral nail
(PFN). Those devices have suffered a varietyof complications like cut-out, screw back out,
COMPLICATIONS
Complications with intertrochanteric fractures arise primarily from fixation rather than union or
LOSS OF FIXATION: Helical blade cutout from the femoral head generally occurs within 3
18
Prevent the excessive collapse of the Proximal fragment
Failure management
less than 2% of patients; its rare occurrence is largely due to the fact that the fracture occurs
stabilization, with subsequent varus collapse, screw cutout through the femoral head. Another
fracture impaction, but this is less with PFN A II. Intertrochanteric nonunion should be
suspected in patients with persistent hip pain that have radiographs revealing a persistent
radiolucency at the fracture site 4 to 7 months after fracture fixation. Progressive loss of
alignment strongly suggests nonunion, although union may occur after an initial change in
present making the diagnosis of nonunion difficult to confirm. Tomography evaluation may
help to confirm the diagnosis; otherwise the diagnosis may not be possible until the time of
surgical exploration. As with any nonunion, the possibility of an occult infection must be
considered and excluded. In some cases, with good bone stock, repeat internal fixation
combined with a valgus osteotomy and bone grafting can be considered however, in most
19
intertrochanteric fracture fixation is internal rotation of the distal fragment at surgery. In
unstable fracture patterns, the proximal and distal fragments may move independently; in such
cases, the distal fragment should be placed in neutral to slight external rotation during fixation of
the plate to the shaft. When malrotation is severe and interferes with ambulation, revision
surgery with plate removal and rotational osteotomy of the femoral shaft should be considered.
OTHER COMPLICATIONS
has been established between location of the implant within the femoral head and the
development of osteonecrosis, although one should avoid the insertion of hip screw in the
postero-superior aspect of the femoral head because of the proximity of the lateral epiphyseal
artery system.
Laceration of the superficial femoral artery by a displaced lesser trochanter fragment has been
reported, as well as binding of the guide pin within the reamer, resulting in guide pin
Nails had very large distal locking screw near the tip of the Nail with associated risk of stress
riser near the Nail Tip causing post operative femoral shaft fracture near the Nail tip. In PFN A
II stress riser effect is decreased by the tapered distal end of the Nail and the distal locking
20
REVIEW OF LITERATURE
Although fractures of hip were known since time of Hippocrates, Sir Astley Cooper (1822)
was the first to have given the accurate description of fracture occurring at proximal femur
and who has distinguished extra capsular from intra capsular fractures many decades before
Percival Pott at the end of 18th century was the first to stress the need of exerting traction in
fractures of upper end of femur. Steinmann in 1907 devised the metallic traction which
Invention of tri-flanged nail for internal fixation of fractures of femur by Smith Peterson
(1925) was the major breakthrough in field of internal fixation device for trochanteric
fractures.57
Thornton (1937) added an adjustable side plate to the S.P nail and thus made it possible to
[12] [13]
Boyd and Griffin (1949), Fielding and Magliato (1966), Zickel (1976), suggested
Mervyn Evans (1951) classified fractures into stable and unstable group thus putting
emphasis on stability of the fracture which is very important for deciding line of management
Raymond and Tronzo described new classification of fracture, classifying it into 5 different
types keeping in mind the anatomy of fracture which is becoming more acceptable
internationally at present.61
Jewett (1952) recommended that all hip fractures be treated with 135 degree nail plate
device. He also developed the fixed-angled nail plate which was initially biflanged and
later on changed to triflanged. As they do not allow controlled collapse and impaction at the
fracture site, without penetration of the femoral head, a stable reduction (anatomical or non
Taylor G.M. (1955) was the first to talk of various deformities resulting from fractures. He
stated that varus deformity is symptomatic when the neck shaft angle is less than 120
degrees.63
Clawson DK in 1959 with help of Richards manufacturing company invented the sliding
compression screw device which is the second major breakthrough in the field of internal
fixation devices for fractures. In 1959, AO blade plates were developed by ASIF. They
advised the device to be effective, must function as tension band, with presence of prompt
Dimon and Hugston (1964) have suggested an easier way of achieving stability, the medial
displacement technique.65
Weismann et.al (1964) were fixing the lesser trochanter in order to achieve anatomical
reduction.66
Wardie (1967) has stated that reduction and fixation of displaced lesser trochanter fragment
to femoral shaft in order to provide a stable buttress for reduction to proximal fragment is
22
difficult time consuming and often unsuccessful.67
Singh (1970) introduced the method of examining the degree of osteoporosis by x-ray
Green et al (1986) and Stern et al (1987) have presented a series of comminuted fractures
treated with Leinbach prosthesis and concluded that it is recommended for the elderly
Russel Taylor (1990) introduced reconstructed intramedullary nail for pertrochanteric and
subtrochanteric fractures63
RJ Medoff in 1990 designed a device that allows axial compression through the neck
portion and through the metaphyseal subtrochanteric portion through a sliding device that is
incorporated onto the plate attachment to the shaft of femur. The compression slide acts as a
intermediate segment, capturing the lag screw proximally and .engaging the barreled side
plate distally in a sliding track. The barreled side plate is attached to the femoral shaft with
the bone screws directed into two planes. This is called “The axial compression screw plate
device”.71
Halder and Williams in 1992 introduced Gamma Nail and Parker described complications
23
of Gamma nail. S.C. Halder in 1992 published paper on the Gamma nail for peritrochanteric
fractures.2
and therefore recommended anatomical reduction and fixation by the sliding hip screw in
most cases.72
fractures of the femur with DCS. In 1994 an author studied about pertrochanteric and
subtrochanteric fractures of the femur treated with Zickel nail. Zickel nail is not been
fractures.73
In 1995, Butt M.S. Krikler S J, Nafie, Ali studied the comparisons of Gamma Nail and
DHS and found that clinical and radiological union results with both implants were the same
but the rate of complication with Gamma Nail was higher .74
simple method to describe the position of the lag screw. The optimal placement of the lag
screw was in the centre/centre position.The correct placement of the lag screw and helical
blade at the centre of the femoral head and neck is important in both the antero-posterior and
axial views; in this the tip apex distance (TAD) In their study, to determine the value of this
24
measurement in prediction of the so called cut out of the lag screw the average tip apex
In 1996, the AO/ASIF developed the proximal femoral nail (PFN) as an intramedullary
device for the treatment of unstable per-, intra- and subtrochanteric femoral fractures in order
to overcome the deficiencies of the extramedullary fixation of these fractures. This nail has
moment arm, can be inserted by closed technique, which retains the fracture hematoma an
important consideration. in fracture healing, decreases blood loss, infection, minimizes the
subtrochanteric fractures and found that the PFN could bear the highest loads of all devices.
Takigami et al in 2008 found that the surgical time and operative blood loss were lower with
the use of PFNA as compared to PFN. They also found the cut out rates of 2% with PFNA2
Sahin et al in 2010 found cut out rates of4.7% in their study. They reported successful
outcome and low complication rates in PFNA2 in unstable per trochanteric fractures when
Geller et al. in 2010 reported 44% of cut outs in intertrochanteric fractures fixation with TAD
of > 25 mm and did not cut out with TAD of < 25 mm.78
Mora et al in 2011 recommend PFNA2 for treatment of trochanteric fractures in the elderly
25
Zeng et al in 2012 found that PFNA use was associated with a significant reduction in
duration of surgery, overall complication rate, post-operative fixation failure rate, and
Andruszkow H , et al in 2012 showed that Tip apex distance, hip screw placement, and neck
shaft angle as potential risk factors for cut-out failure of hipscrews after surgical treatment of
intertrochanteric fractures.81
Boopalan et al.in 2012 reported 21% incidence of intra operative lateral wall fractures in 31
A1 and A2 pertrochanteric fracturefixation. The fracture union was not affected by the
[35]
In 2012 Soucanye de landevoisin and E.Demortiere study showed PFNA was best in
Aguado - Maestro et al in their study of 200 patients in 2013, treated with PFNA found that
helical blade device reduced the rate of cut out & accurate placement of helical blade was key
Rubilo-Avila J, et al in 2013, in a systematic review found that Tip apex distance is one of the
General Objective:
To analyse the short term functional outcome of PFNA-II used in the treatment of
26
Specific Objective:
2.To assess functional outcome of the treatment using Harris hip score
27
METHODOLOGY
Study design: This was a prospective observational study carried out in the department
approval from institutional review board. An informed consent was obtained from the
patients. All the data were collected from the patients during their stay in the
hospital, during follow up at regular intervals and from the medical records. The
n0 =Z2pq/d2(cocharan 1997)
where,
Z is the confidence level set at 95% which is 1.96(Z =1.96 for 95% CI)
I could not find any exact literature on my study giving necessary informations on sample
size.The total cases presented to NMCTH last year was 30 so my sample size would be 30.
Inclusion criteria
28
- All unstable types of fracture pattern AO/OTA type 31A2.2 to 31A3.3 [4]
- Different mode of injuries i.e. fall from standing height, slippage, road traffic accident, -fall
Exclusion criteria
- Pathological fractures.
- Patients with intertrochanteric femur fracture treated with other modalities of internal
fixation.
Management: A detailed history was taken. Mode and mechanism of injury was
elicited. Associated injuries were assessed. A detailed physical examination was done.
X – rays of the hip including thigh in AP and lateral views were taken.
Skin/skeletal traction was applied. Pain mangement was done with IV analgesics.
29
Preoperative investigations were done and the patients were assessed by
anesthesiologists department for the fitness for surgery. Medically unfit patients were
Intra - operative protocol: All patients were taken to the operation theatre only after
the informed consent of anesthesia and surgery. All patients were given IV cefuroxime
spinal with/ without epidural anesthesia over fracture table. C - arm image intensifier was
Surgical technique: After anesthesia all the patients were kept in fracture table. Fracture was
reduced under image guidance. The affected limb was kept 10-15˚ of abduction for easy nail
insertion. Tip of greater trochanter was identified and skin incision was made 5 cm
proximally. Bone awl was used to make the entry point at the tip of trochanter and guide wire
was inserted. The position of wire was checked in image in both AP and lateral views. The
soft tissue was protected and intramedullary reaming was done using flexible reamers. The
appropriate diameter and length of nail was attached to the insertion handle and inserted into
the femur. The guide wire was removed. The 130˚ aiming arm was attached to the insertion
handle and guide wire for helical blade was inserted through small lateral incision. Central
position of blade guide wire in both AP and lateral view was checked. The length of helical
blade was measured and the cortex was drilled with 11 mm cannulated reamer. The
appropriate size helical blade was inserted over guide wire by gentle blow with hammer and
locked by turning the impactor clockwise. The distal locking of nail was done. Closure of the
30
Post - operative protocol: Quadriceps exercise and knee ROM was started from first
postoperative day. First dressing was done on 3 rd postoperative day. Patient was mobilized
non weight bearing in walker or crutches.Sutures were removed on 14th postoperative day.
Weight bearing increased gradedly on the basis of degree of discomfort or apprehension that
such weight bearing causes(self protected weight bearing). Patient was followed up at the
interval of 6 weeks, 3 months and 6 months. Harris hip score (HHS) was used for functional
Statistical Analysis : The data was entered in Microsoft Excel and converted into
Statistical Package for Social Sciences (SPSS-21) for statistical analysis. For descriptive
data analysis percentage, mean, SD, minimum and maximum were calculated along
with tubular and graphical presentation . For inferential data analysis , one - way
ANOVA test was applied to find the significant differences between the scale
(numerical) variables and the nominal (categorical) variables ; Pearson Chi – square test
was used to find the statistical differences between two nominal ( categorical )
variables, and if could not be applied due to >20% of cells having expected counts
<5, Fischer exact test was used. And if Fischer exact test could not be used then
Likelihood ratio was used to find the significance of an association. CI was set at
31
32
RESULT
A prospective observational study was carried out to evaluate the results of short term
(PFNA-II) in a total of 30 patients those fulfilling the inclusion criteria and following
In this study mean age was aproximately 72.33±7.7years. As far as the sex ratio is concerned,
11 were males and 19 were females. There was no significant relation of sex with the
Sex Distribution
37%
Male
Female
63%
34
Mode of injury:
The fracture was highly associated with self fall accounting for 63.3 % of cases and the
remainder were associated with road traffic accident (RTA). There was no significant
association between the mode of injury and the functional outcome (p=0.4).
35
Side of injury:
In this study 63.3 % of the patients sustained injury in the left side and 36.7% on the right
side. There was no significant association between the side of injury and functional outcome
(p>0.05).
Side of Injury
20
18
16
14 No of patients
12
10
8
6
4
2
0
Left Right
36
Type of Fracutures (AO classification):
In this study, the majority of the fractures were found to be 31A2.3 (60%) followed by
31A3.3 (20%). There was no significant association between the AO type and functional
outcome (p=0.5).
31A3.3 6 20
Total 30 100.0
AO Classification
13%
20%
A2.2
A2.3
A3.2
7%
A3.3
60%
37
12
10
6 Male
Female
0
A2.2 A2.3 A3.2 A3.3
38
Duration from time of injury to surgery:
In these 30 patients, surgery was performed within 2-9 days (average 5.30 days). There was
Primary outcome: All fractures united within expected time at an average of 13±1.2 weeks
Secondary outcome: There was 1 case of scre back-out at 2 weeks for which revision
The average Harris Hip score at final follow up was 82.40±5.50 (range 72-90). Out of 30,
10% patients had excellent, 76.7% had good and 13.3% had fair results
39
Functional Outcome
Excellent
No of patients
Good
Fair
0 5 10 15 20 25
40
DISCUSSION
just like the conventional PFN, more stiff, having shorter moment arm i.e. from the tip of
helical blade to the center of femoral canal with lesser incidence of varus malunion
incorporating the principles and theoretical advantages over Dynamic hip screw and many
The larger proximal diameter (17 mm) of the PFNA-IIcompared with PFN (15 mm) gives
additional stiffness to the nail. Minimal blood loss, shorter operative time, early weight
bearing, less chances of implant failure, minimal fluoroscopy time, easier helical blade
insertion (compared with cumbersome lag screw and derotation screw), lesser chances of post
op hip pain, better performance than any other implant in elderly osteoporotic patients are all
In the current study the union rate was 100%. There were no cases of preoperative and
Average operating time in our series was 62.6 minutes. (Range 39 – 97 min) was comparable
41
The use of image intensifier was 13.0 shots (Range: 8 to 20) in patients treated with the PFN,
The time to union was 13.0 weeks (Range: 12 to 16 weeks) in our study comparable to that
of Levent karapinar et.al. and Li J. et al and lesser than that of Yu. W. Zhang et al (14 weeks )
The average HARRIS HIP SCORE in our patients was 82.4 (at the end of 6 months) and
82.3. Most of them were graded as “good” as per HARRIS HIP SCORING.
88
Leventkarapinar et al -80.75
Yu.W.Zhang et al 86 -81.90
Average HARRIS HIP Our series - 82.3
SCORE Li J et al 89 - 86.19
One case of screw cut out (3.3%) was reported in our study. in few cases Two cases of helical
blade cut out (out of 42 patients, i e, 4.7%) was reported by Levent karapinar et al. 88 There
were no cases of non-union reported in our study comparable to that of Levent karapinar et
al.88
Peroperative and postoperative Femoral fractures have been documented in patients treated
with the PFN and PFN A-II. Multiple factors have been implicated like implant design and.
operative technique. Decreases in implant curvature, diameter, over reaming of femoral canal
by 1.5 to 2mm, insertion of the implant by hand and meticulous placement of the distal
locking. Screws without creating additional stress risers decreases the complication rate of
femoral shaft fracture (I.B. Schipper et al 2004)90. Patients with narrow femoral .canal and
implants (Halder et al 1992).2 We have followed these recommendations in our series. Hence
42
in our series we don’t have encountered any preoperative and postoperative femoral. shaft
43
CONCLUS
ION
Intramedullary nailing with the PFNA-II has distinct advantages over Conventional PFN or
DHS like shorter operating time and lesser blood loss for elderly, osteoporotic unstable
trochanteric fractures.
Early mobilization and weight bearing is allowed in patients treated with PFNA-II thereby
Good preoperative planning, correct surgical technique, adequate reaming of the femoral
canal, insertion of implant and meticulous placement of distal locking screws can further
reduce the incidence of postoperative femoral shaft fractures, non-union rates in PFNA-II.
PFNA-II is a significant advancement in the treatment of trochanteric fractures which has the
unique advantage of closed reduction, preservation of fracture hematoma, minimal soft tissue
In short the PFNA-II is a better implant with specific design superior to conventional PFN
and with distinct advantages over other implants to treat intertrochanteric fractures. With
adequate surgical technique, the advantages of the PFNA-IIincreases and the complication
rate decreases.
44
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APPENDIX
NOBEL MEDICAL COLLEGE TEACHING HOSPITAL
CONSENT
I,.…………………..………..................grandson/granddaughter
56
of ............................. district...............................V.D.C/ municipality, have been well
informed about the illness. I am willing to get treated at NMCTH and have no objection for
relevant investigations and treatment. The information will be utilized for study purpose and I
undersign giving a valid written consent of no objection for investigation and treatment.
........................................
Signature
Name: .................................
I, Dr. Suraj Shahi, will keep the above mentioned information confidential and sole use for
research purpose.
.....................................
PROFORMA
Personal Data:
Name:
Age:
Sex:
Occupation:
57
Address:
IP Number:
Mechanism of injury:
Past history:
General Condition:
Pulse Rate
Blood Pressure
Respiratory Rate
Systemic Examination:
CVS/RS/CNS/PA:
Local Examination:
Condition of skin
Presence of wound
Presence of infection
58
Neurovascular deficits
Immediate post op
0-3mm(good) 3- >5mm(poor)
5mm(acceptable)
Fracture gap
present Absent
cut-out or lateral migration of helical
blade
Infection
At 6 weeks
0-3mm(good) 3- >5mm(poor)
5mm(acceptable)
Fracture gap
present Absent
cut-out or lateral migration of helical blade
Infection
Secondary varus development
Persistent limp
Heterotopic ossification
At 3 months
Fracture gap 0-3mm(good) 3- >5mm(poor)
5mm(acceptable)
present Absent
cut-out or lateral migration of helical blade
Infection
Secondary varus development
Persistent limp
Heterotopic ossification
At 6 months
Fracture gap 0-3mm(good) 3- >5mm(poor)
5mm(acceptable)
59
present Absent
cut-out or lateral migration of helical blade
Infection
Secondary varus development
Persistent limp
Heterotopic ossification
60
Harris hip score at 6 months follow up
61
Figure 15 : Intraop fluoroscopic image
63
Figure 17 : Post op xray
64