New on NCI’s Websites for December 2021

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December 29, 2021,
by NCI Staff

NCI’s collection of cancer information products is constantly

growing, so we provide periodic updates on new and updated
content of interest to the cancer community.

Videos: The First Lady and NCI on the

50th Anniversary of the National
Cancer Act
The signing of the National Cancer Act of 1971 on
December 23 of that year opened the door to 50 years of
tremendous progress in the nation’s fight against cancer.
Two new videos commemorate that progress and look
ahead to the promise of further advances. In the first, First
Lady Dr. Jill Biden highlights how the investment in people and science spurred by the National Cancer Act
has led to many important advances, and she describes the administration’s commitment to ending cancer
as we know it. The second video outlines the progress in areas like prevention, treatment, and survivorship
and NCI’s plans to build on these advances and ensure progress across all cancers and for all people.

News Release: Drug Combination Helps Children with APL Avoid

Conventional Chemotherapy
A Children’s Oncology Group clinical trial has found that the combination of all-trans retinoic acid and arsenic
trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.
Nearly all patients in the trial survived for 2 years without their cancer returning.

News Release: High-Fiber Diet May Improve Melanoma Patients’

Response to Immunotherapy
A diet rich in fiber may help some people being treated for melanoma respond to immunotherapy treatment
by influencing the gut microbiome, according to a new study led by researchers at NCI’s Center for Cancer
Research and the University of Texas MD Anderson Cancer Center. Results from the study, which analyzed
both people with melanoma and mouse models of the disease, appeared December 24, 2021, in Science.

Studies Focus on Testing Family Members of People with Cancer-

Related Genetic Changes
If your family member had cancer, would you want to know if you carry a genetic mutation that increases
your risk of the same cancer? This question is at the heart of three research projects underway to determine
the best way for researchers to find relatives of women previously diagnosed with ovarian cancer so they can
decide whether to get genetic testing and counseling about their own risk of cancer.

NCI Bottom Line Blog: Familiar Fiscal Challenges for NCI

On December 2, Congress passed a new continuing resolution to provide funding for the federal government
at fiscal year 2021 levels until February 18. In this blog post, NCI Director Norman Sharpless, M.D., explains
what the continuing resolution means for NCI’s grantee community and how it affects both competing and
noncompeting grants.

Center for Global Health Website Refresh

Cancer is a global public health priority. Given that NCI is the world’s leading supporter of cancer research, it
has a unique role to play in generating knowledge and contributing to the global control of cancer. The
Center for Global Health (CGH), NCI’s global health hub, recently launched its newly redesigned and
enhanced website. The refreshed site features new and expanded content, tools for social media sharing,
and much more.

NCIDose Radiation Dosimetry Tools

The NCIDose collection of medical radiation dosimetry tools allow researchers to estimate the dose of
radiation a patient received while undergoing diagnostic or therapeutic procedures. These tools, developed
by health physicists from NCI’s Radiation Epidemiology Branch in the Division of Cancer Epidemiology and
Genetics, are available free of charge for noncommercial research purposes.

Video: The Effect of Diet and Exercise on Immunotherapy and the

Microbiome (EDEN Study)
NCI’s Center for Cancer Research is conducting a trial to investigate the link between diet, exercise, and
changes in the gut microbiome that may improve the efficacy of immunotherapy. The Effect of Diet and
Exercise on Immunotherapy and the Microbiome (EDEN) clinical trial will enroll people with melanoma that
cannot be removed by surgery. All visits will be conducted via telehealth, so participants can enroll from
anywhere and will not need to travel to a trial site. 

Video: Discovering Drivers of Childhood Cancer

Dr. Kimberly Stegmaier of Dana-Farber Cancer Institute describes the progress her research team has made
in Ewing sarcoma. Her team's work targeting the EWS-FLI fusion, one of the fusion oncoproteins that drives
childhood cancers, addresses one of the recommendations made by the Cancer Moonshot℠ Blue Ribbon
Panel.

Cancer in Children and Adolescents

NCI’s Cancer in Children fact sheet has been revised and expanded to include information about cancer in
adolescents, including updated statistics. Information was also added about racial and ethnic differences in
rates of common cancers in this age group, potential causes of cancer in children and adolescents, genetic
studies and testing, and navigating care for long-term survivors.
 < Older Post Newer Post >
Black Patients Are More Likely to Die of Cancer—Here’s FDA Oversight of E-Cigarettes Gathers Speed: A
How One Group Is Tackling That Conversation with Mitch Zeller

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