The Cartagena Protocol on Biosafety (CPB) AKA Cartagena Protocol was developed

as an addendum and came into force in 2003. Basically, it is an international

requirement to ensure the safe transport and use of products of GMO or genetically
modified organisms. 
30 years ago, when the scientists discovered agrobacterium, which is a tool for
introducing novel genes into plants, science scholars have gone craze for more new
breed and genetic discoveries. Initially, from red apples to brussels until citizens got
worried about the probable strange effects of GMO which is exactly why CPB was
created for.
The Cartagena Protocol is significant because it addresses "biosafety, with a
particular emphasis on transboundary movement of any living is modified organism
resulting from modern biotechnology that may have an adverse effect on the
conservation and sustainable use of biological diversity."
Swedish authorities initially regarded CRISPR, the molecular scissor invented at
Umeà University, as a mutant rather than a GMO. While people continued to rally
against it, they accepted it because, as Steffan Jansson put it, "it does not make
sense to have a law where only those who exactly describe the crime to the court
can be sentenced."
Indeed, GMO has a lot of issues. It is risky, for it may have the ability to
evade detection and possibly introduce engineered genes into wild populations. The
genes may have the ability to survive after the GMO has been harvested and non-
target species' resistance. 
CPB, as the Biosafety Protocol, protects biological from the risks posed by
genetically modified organisms (GMOs) created by modern biotechnology.It has
become an indispensable weapon for those who wish to block some new scientific
discovery that they oppose, in its most popular use "where an action poses risks of
harm to the environment or human health, precautionary steps should be taken even
though certain cause and effect associations are not completely known scientifically."