Tables

Table Page
Title
No. No.

1. Summary of the history of Diabetes mellitus 2

2. The results of glucose analysis in glucose tolerance test 7

3. Pancreatic islets house have four major cell types 8

4. Some plants having hypoglycemic activity 16

5. List of antidiabetic agents from natural origin 36

6. List of chemicals/ solvents used 51

7. List of equipments/instruments used 53

8. List of glasswares used 54

9. Most probable total count by multiple-tube or serial dilution method. 59

10. Test for Salmonella typhi 61

11. Tests for Pseudomonas aeruginosa 62

12. Test for Staphylococcus aureus 62

13. Grouping scheme for antidiabetic Study 79

14. Procedure for estimation of total cholesterol 81

15. Procedure for estimation of HDL cholesterol. 82

16. Procedure for estimation of triglycerides 84

The details of column chromatography of Pet. ether extract of Careya

17. 93
arborea Roxb
Elution scheme for column chromatography of Pet. ether extract of Careya
18. 94
arborea Roxb

The details of column chromatography of alcoholic extract of Careya

19. 98
arborea Roxb
The details of column chromatography of alcoholic extract of Bridelia
20. 102
retusa Spreng

v
 Tables

Table Page
Title
No. No.
Elution scheme for column chromatography of alcoholic extract of Bridelia
21. 102
retusa Spreng

22. Behavioural characters of powdered bark of Careya arborea Roxb 108

111
23. Physical constants of Careya arborea Roxb. bark

111
24. Determination of moisture content of Careya arborea Roxb. bark

112
25. Microbial contamination test for Careya arborea Roxb. bark

Tests for presence of specified microorganisms of Careya arborea Roxb.

26. 112
bark

27. Extractive values for Careya arborea Roxb.bark 112

Results of qualitative chemical investigation for extracts of Careya arborea

28. 113
Roxb. bark

29. Behavioural characters of powdered bark of Bridelia retusa Spreng 117

30. Physical constants of Bridelia retusa Spreng.bark 120

31. Determination of moisture content of Bridelia retusa Spreng. bark 120

32. Microbial contamination test for Bridelia retusa Spreng.bark 121

Tests for presence of specified microorganisms of Bridelia retusa Spreng.

33. 121
bark

34. Extractive value for Bridelia retusa Spreng.bark 121

Results of qualitative chemical investigation for extracts of Bridelia retusa

35. 122
Spreng. bark

36. Parameters for titrations 125

37. Mean volume (in ml) at equivalence point for the titrations 125

38. LD50 and the effective doses of Careya arborea Roxb. bark 126

vi
 Tables

Table Page
Title
No. No.

39. Grouping scheme for antidiabetic study of Careya arborea Roxb.with doses 127

Effect of control on blood sugar (mg/dl) of normal animals at 0hrs, 2hrs,

40. 128
4hrs and 6hrs interval
Effect of diabetic control on blood sugar (mg/dl) of diabetic animals at 0hrs,
41. 128
2hrs, 4hrs and 6hrs interval
Effect of pet. ether extract of Careya arborea Roxb.on blood sugar (mg/dl)
42. 129
of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of benzene extract of Careya arborea Roxb.on blood sugar (mg/dl) of
43. 129
diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of chloroform extract of Careya arborea Roxb.on blood sugar
44. 130
(mg/dl) of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of acetone extract of Careya arborea on blood sugar (mg/dl) of
45. 130
diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of ethanol extract of Careya arborea Roxb.on blood sugar (mg/dl) of
46. 131
diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs. interval
Effect of aqueous extract of Careya arborea Roxb.on Blood Sugar (mg/dl)
47. 131
of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs. interval
Effect of alcoholic extract of Careya arborea Roxb. on blood sugar (mg/dl)
48. 132
of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of glibenclamide on blood sugar (mg/dl) of diabetic animals at 0hrs,
49. 132
2hrs, 4hrs and 6hrs. interval
Effect of control on blood sugar (mg/dl) of diabetic animals at 1st day, 7th
50. 133
day,14th day and 21st day
Effect of diabetic control on blood sugar (mg/dl) of diabetic animals at 1st
51. 134
day, 7th day,14th day and 21st day.
Effect of pet. ether extract of Careya arborea Roxb.on blood sugar (mg/dl)
52. 134
of diabetic animals at 1st day, 7th day,14th day and 21st day.
Effect of benzene extract of Careya arborea Roxb.on blood sugar (mg/dl) of
53. 135
diabetic animals at 1st day, 7th day,14th day and 21st day.

54. Effect of chloroform extract of Careya arborea Roxb.on blood sugar 135

vii
 Tables

Table Page
Title
No. No.
(mg/dl) of diabetic animals at 1st day, 7th day,14th day and 21st day.

Effect of acetone extract of Careya arborea Roxb. on blood sugar (mg/dl)

55. 136
of diabetic animals at 1st day, 7th day,14th day and 21st day.
Effect of ethanol extract of Careya arborea Roxb. on blood sugar (mg/dl)
56. 136
of diabetic animals at 1st day, 7th day,14th day and 21st day.
Effect of aqueous extract of Careya arborea Roxb. on blood sugar (mg/dl)
57. 137
of diabetic animals at 1st day, 7th day,14th day and 21st day.
Effect of alcoholic extract of Careya arborea Roxb.on blood sugar (mg/dl)
58. 137
of diabetic animals at 1st day, 7th day,14th day and 21st day.
Effect of glibenclamide on blood sugar (mg/dl) of diabetic animals at 1st
59. 138
day, 7th day,14th day and 21st day.
Effect of control group on body weight of normal animals at 1st day, 7th day,
60. 139
14th day and 21st day.
Effect of diabetic control group on body weight of animals at 1st day, 7th
61. 139
day, 14th day and 21st day.
Effect of pet. ether extract of Careya arborea Roxb. on body weight of
62. 140
animals at 1st day, 7th day, 14th day and 21st day.
Effect of alcoholic extract of Careya arborea Roxb. on body weight of
63. 140
animals at 1st day, 7th day, 14th day and 21st day.
Effect of aqueous extract of Careya arborea Roxb. on body weight of
64. 141
animals at 1st day, 7th day, 14th day and 21st day.
Effect of glibenclamide on body weight of animals at 1st day, 7th day, 14th
65. 141
day and 21st day.
Effect of Careya arborea Roxb. bark extracts on other biochemical
66. 143
parameters
Effect of Careya arborea Roxb.bark extracts on blood glucose level in oral
67. 144
glucose tolerance test (OGTT)

68. α-glucosidase inhibitory activity of extracts of Careya arborea Roxb.bark 145

69. Anticancer activity of Careya arborea Roxb. extracts by MTT assay 146

viii
 Tables

Table Page
Title
No. No.

70. IC50 values of extracts of Careya arborea Roxb.for anticancer activity 146

71. LD50 and the effective doses of Bridelia retusa Spreng. bark 147

Grouping scheme for antidiabetic study of Bridelia retusa Spreng. with

72. doses 148

Effect of diabetic control on blood sugar(mg/dl) of diabetic animals at 0hrs,

73. 2hrs,4hrs and 6hrs interval 149

Effect of pet. ether extract of Bridelia retusa Spreng. on blood sugar(mg/dl)

74. 149
of diabetic animals at 0hrs, 2hrs,4hrs and 6hrs interval
Effect of benzene extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
75. 150
of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of chloroform extract of Bridelia retusa Spreng. on blood sugar
76. 150
(mg/dl) of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of acetone extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
77. 151
of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of ethanol extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
78. 151
of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of aqueous extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
79. 152
of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of alcoholic extract of Bridelia retusa Spreng. on blood sugar
80. 152
(mg/dl) of diabetic animals at 0hrs, 2hrs, 4hrs and 6hrs interval
Effect of glibenclamide on blood sugar (mg/dl) of diabetic animals at 0hrs,
81. 153
2hrs, 4hrs and 6hrs interval
Effect of diabetic control on blood sugar (mg/dl) of diabetic animals at 1st
82. 154
day, 7th day,14th day and 21st day
Effect of pet. ether extract of Bridelia retusa Spreng. on blood sugar
83. 154
(mg/dl) of diabetic animals at 1st day, 7th day,14th day and 21st day
Effect of benzene extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
84. 155
of diabetic animals at 1st day, 7th day,14th day and 21st day

ix
 Tables

Table Page
Title
No. No.
Effect of chloroform extract of Bridelia retusa Spreng. on blood sugar
85. 155
(mg/dl) of diabetic animals at 1st day, 7th day,14th day and 21st day
Effect of acetone extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
86. 156
of diabetic animals at 1st day, 7th day,14th day and 21st day
Effect of ethanol extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
87. 156
of diabetic animals at 1st day, 7th day,14th day and 21st day
Effect of aqueous extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
88. 157
of diabetic animals at 1st day, 7th day,14th day and 21st day
Effect of alcoholic extract of Bridelia retusa Spreng. on blood sugar (mg/dl)
89. 157
of diabetic animals at 1st day, 7th day,14th day and 21st day
Effect of glibenclamide on blood sugar (mg/dl) of diabetic animals at 1st
90. 158
day, 7th day,14th day and 21st day
Effect of control group on body weight of normal animals at 1st day, 7th day,
91. 159
14th day and 21st day
Effect of diabetic control group on body weight of animals at 1st day, 7th
92. 159
day, 14th day and 21st day
Effect of alcoholic extract of Bridelia retusa Spreng. on body weight of
93. 160
animals at 1st day, 7th day, 14th day and 21st day
Effect of aqueous extract of Bridelia retusa Spreng. on body weight of
94. 160
animals at 1st day, 7th day, 14th day and 21st day
Effect of glibenclamide on body weight of animals at 1st day, 7th day, 14th
95. 161
day and 21st day
Effect of Bridelia retusa Spreng. bark extracts on other biochemical
96. 162
parameters
Effect of Bridelia retusa Spreng..bark extracts on blood glucose level in oral
97. 163
glucose tolerance test (OGTT)

98. α-glucosidase inhibitory activity of extracts of Bridelia retusa Spreng 164

99. Anticancer activity of Bridelia retusa Spreng. extracts by MTT assay 167

100. IC50 values of extracts of Bridelia retusa Spreng.for anticancer activity 167

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 Tables

Table Page
Title
No. No.
Total phenol and flavonoid contents of extracts of Careya arborea Roxb.
101. 168
bark

102. Free radical scavenging activity of Careya arborea Roxb. bark 169

103. Identification and estimation of lupeol by HPTLC 173

104. IR study of Lupeol 175

105. NMR study of Lupeol 177

Identification and estimation of quercetin of Careya arborea Roxb. by

106. 182
HPTLC

107. IR study of quercetin 185

108. NMR study of quercetin 186

109. Total phenol and flavonoid content of extract of Bridelia retusa Spreng.bark 189

110. Free radical scavenging activity of Bridelia retusa Spreng. bark 190

111. Identification and estimation of β-sitosterol by HPTLC 194

112. IR study of β-sitosterol 196

113. NMR study of β-sitosterol 199

Identification and estimation of quercetin of Bridelia retusa Spreng.by

114. 202
HPTLC

xi