CH3 Hz Geometrical

CHz C O t Han OH c
isomerism
11
CHz N is not
OH possible
Ketoxime
N OH
NH OH

Ht
Beckmann
Rearrangement

N methyl propana Gits

É NH CHz
mide
CHz NH GHS É
N ethyl Ethanamide
The acid catalyzed conversion of Ketoxim
es to N substituted amides is known as

Beckmann rearrangement
The reaction involves the migration
of a group from carbon to electron deficient
nitrogen
The reaction is
catalysed by the acidic
reagents such as 42504 50012 503 1205
 PC15 6455042 Polyphosphoric acid etc

migration of the group depends no

The
on the migrational aptitude but upon the
orient tion
of the group in relation to the OH group
The reaction is Stereospecific
MECHANISM

Hz 845
C
Ht

o Fit
H2O

C2Hs
845

G
Hz C
11
N
CH3
Ne
H2O electron deficient
Nitrogenspecies
Hot
GHS HO 45
C
11 HO C

N 11
N
CHz
CHz
Tautomerism

12115
C
for SH5CONACH
Ny
Nmethyl
CH propanamide

6245 CH3 845 CHz

c a
Ht

N
OH THz

H2O

CH3
I 5 CH3
11
 N
ya

H2O electron deficien

NitrogenSpecies

Hat
CH3 CH
C HO
11 HO C

N 11
N
6245
845
Tautomerism

Hz
C
for CH3CONHGHS
µ N ethyl
Gits Ethanamide

The retains its

migrating group
i e config ration
if migrating group has chiral
carbon its configuration will not change
due to migration
 Migrating groups are
migrated by
concerted path

OH Cu 3007

2 Han OH
caprolactum
Ht O
cyclic amide
H2O on
pol merisation

0 Peston
N polymer
NYLON 6
Cyclohexane

Han OH

Io He É

CHzCHzCHO t Semicarbazide HANNA NH

G

Ans CH CH CH N NH CONHZ
 Ht Me
A t B 8450

Me 0845
Ans A One mole of Acetone
B 2 mole of CaH5OH

Ht Calts
A t B 8450

Me Ome
Ans A One mole of Butanone
B 1 mole of CHzOH I mole of GH5OH

Q
Me I on I HCN
Me CH3 Hz
Ke K

Me I on I HCN
CH H
H
Kc Kz
Relation between K and ka is
1 K Kz 2 K Kz 3 Kz ki
4 Data insufficient
Q
O 111 KEN 42504
product
H 2 LAING

Identify the product

 OH OH
1 2

Pr CHzNHz Me NHz

pr
3 4 A and C are
correct
pr
NHz
H

Q C Nat He

Hz
CEC CH

OH
Q OO Ht
ea

O 2 MeMgBr
H
Hot
CH3
Ans
o CHzingBr OmgBr 1300
y 1
O O
O CH3 Hz
0
OH

2 Hydroxy CHO
2
methyl
Propanol
Q A carbonyl compound has molecular not 100
Among ketonic isomers of that compound
how will undergo Haloform reaction
many
M F 664120
it
2 Hexanone

8
i i

8
8
Q
1,2 dichloro
Alc In
ethane
H2O Ht IUPAC name of final
Cu 3007 product

HCN

Hydrolysis
CHz Li 3 mole
 y y

CHz CHz CHz CHz OH

Catz CHO city IT CEN

City
dit I oh 24th
super
city III hit

Grigngedagent Caste

excited 430
cats I low
Hz dits
city
dit I CH 3 Hydroxy
2 Butanone