Republic of the Philippines

Cebu Normal University

Osmeña Blvd. Cebu City, 6000 Philippines

College of Nursing
Center of Excellence (COE) | Level IV Re-Accredited (AACCUP)
Telephone No.: (032) 254 4837
Email: cn@cnu.edu.ph/secretary@cnunursing.org
Website: www.cnu.edu.ph
DRUG STUDY

Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing
Responsibilities
Generic Name: PHARMACOT Action PO, injection, Hypersensitivity to ketorolac, Frequent (17%–12%): Baseline assessment
Ketorolac HERAPEUTIC: Inhibits prostaglandin nasal: Short-term aspirin or other NSAIDs. Headache, nausea, abdominal Assess onset, type,
NSAID. synthesis, reduces (5 days or less) Intracranial bleeding, cramps/pain, dyspepsia. location, duration of
prostaglandin levels in relief of mild to hemorrhagic diathesis, pain. Obtain baseline
CLINICAL: aqueous humor. moderate pain. incomplete hemostasis, high Occasional (9%–3%): renal/hepatic
Brand risk of Diarrhea. function tests.
Analgesic,
Name(s): Ophthalmic: bleeding; concomitant use of Intervention/evaluatio
intraocular anti-
Acular Therapeutic Effect: Relief of ocular aspirin, NSAIDs, probenecid Nasal: Nasal discomfort, n
inflammatory.-
Acular LS Reduces intensity of itching due to or pentoxifylline; rhinalgia, increased
inflammatory. pain stimulus, reduces seasonal allergic labor and delivery, advanced lacrimation, throat irritation, Monitor renal function,
intraocular conjunctivitis. renal impairment or risk of rhinitis. LFT, urinary output.
inflammation. Treatment postop renal failure, active or
for inflammation history of peptic ulcer disease, Ophthalmic: Transient Monitor daily pattern of
following cataract chronic inflammation of GI stinging, burning. bowel
Pharmacokinetics extraction, pain tract, recent or activity, stool
Readily absorbed from following history of GI consistency.
GI tract after IM incisional refractive bleeding/ulceration. Rare (3%–1%): Constipation,
administration. Protein surgery. Perioperative pain in setting of vomiting, flatulence, stomatitis. Observe for occult
binding: 99%. CABG surgery. blood loss.
Metabolized in liver. OFF-LABEL: Prophylaxis before major Ophthalmic:
Primarily excreted in Prevention, surgery. Ocular irritation, allergic Assess for therapeutic
urine. Not removed by treatment of ocular reactions (manifested by response: relief of pain,
hemodialysis. inflammation pruritus, stinging), superficial stiffness, swelling;
Half-life: 5–9 hrs (ophthalmic form). Cautions: Hepatic ocular infection, keratitis. increased joint mobility;
(increased in renal impairment, history of GI reduced
tract disease, asthma, joint tenderness;

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 impairment, in elderly). coagulation disorders,
receiving anticoagulants, fluid
retention, HF, renal
impairment, inflammatory
bowel disease, smoking, use of
alcohol, elderly, debilitated.
Adverse effects/toxic reactions improved grip strength.
Peptic ulcer, GI bleeding,
gastritis, severe hepatic reaction Monitor for bleeding
(cholestasis, jaundice) (may also occur
occur rarely. Nephrotoxicity with ophthalmic route
(glomerular nephritis, interstitial due to systemic
nephritis, absorption).
nephrotic syndrome) may occur
in pts with preexisting renal
impairment. Acute Patient/ family
hypersensitivity reaction (fever, teaching
chills, joint pain) occurs rarely. • Avoid aspirin, alcohol.
• Report abdominal
pain, bloody stools, or
vomiting blood.
• If GI upset occurs,
take with food, milk.
• Ophthalmic:
Transient stinging,
burning may occur upon
instillation.
• Do not administer
while wearing soft
contact lenses.

Source:
Source: Hodgson, K. J., Kizior, Source:
Hodgson, K. J., Source: R. J. (2019). Saunders Source: Hodgson, K. J., Kizior, R. J. Source:
Kizior, R. J. Hodgson, K. J., Nursing Drug Handbook Hodgson, K. J., Source:
(2019). Saunders Nursing Hodgson, K. J., Kizior,
(2019). Kizior, R. J. 2019. Elsevier. Kizior, R. J. (2019). Hodgson, K. J., Kizior, R. J.
Drug Handbook R. J. (2019). Saunders
Saunders (2019). Saunders Saunders Nursing (2019). Saunders Nursing Drug
2019. Elsevier. Nursing Drug Handbook
Nursing Drug Nursing Drug Drug Handbook Handbook
2019. Elsevier.
Handbook Handbook 2019. Elsevier. 2019. Elsevier.
2019. Elsevier. 2019. Elsevier.

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 This study source was downloaded by 100000821958132 from CourseHero.com on 02-21-2022 04:32:55 GMT -06:00
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