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Red Blood Cells 

(also called erythrocytes or RBCs)


Production of red blood cells is controlled by erythropoietin, a hormone produced primarily
by the kidneys. Red blood cells start as immature cells in the bone marrow. The formation of
a red blood cell takes about 2 days. A fter that rbc will take approximately seven days to
mature. The mature rbc will then be released into the bloodstream. On average, our body
makes about two million red blood cells every second.

White Blood Cells (also called leukocytes)


They have a short life, which normally live only two to three days, or even less than a
day, such as neutrophil. Hence, our bone marrow must constantly make new wbc to
maintain protection against infection. This is the reason why transfusion of wbc is generally
not effective since they do not remain in the body for very long.

Platelets (also called thrombocytes)


Platelets are produced from very large bone marrow cells called megakaryocytes.  As
megakaryocytes develop into giant cells, they undergo a process of fragmentation that results in
the release of over 1,000 platelets per megakaryocyte.  The dominant hormone controlling
megakaryocyte development is thrombopoietin (often abbreviated as TPO). 

With a lifespan of about 8–10 days, platelets are continuously generated


from bone marrow megakaryocytes which release platelets into
the bloodstream to maintain levels of 150,000–400,000 platelets per
microliter of blood.
A red blood cells take about 2 days to form, and the development of stem
cells to mature red blood cells take about 7 days. When matured, in a
healthy individual these cells live in blood circulation for about 100 to 120
days (and 80 to 90 days in a full term infant). At the end of their lifespan,
they are removed from circulation. In many chronic diseases, the lifespan
of the red blood cells is reduced.
the body makes about two million red blood cells every second.
In a normal adult the red cells of about half a litre (almost one pint) of blood
are produced by the bone marrow every week. Almost 1 percent of the
body’s red cells are generated each day, and the balance between red cell
production and the removal of aging red cells from the circulation is
precisely maintained. The rate of blood cell formation varies depending on
the individual, but a typical production might average 200 billion red cells
per day, 10 billion white cells per day, and 400 billion platelets per day.
WBC have a short lifespan, which range from 13 to 20 days, sme of them
even live only two to three days, or even less than a day, such as
neutrophil. Hence, our bone marrow must constantly make new wbc to
maintain protection against infection. This is the reason why transfusion of
wbc is generally not effective since they do not remain in the body for very
long.
Platelets in the bloodstream live approximately 8 to 10 days and are rapidly
replenished. When levels are low, they most often return to normal in
around 28 to 35 days.

Where does blood produce?


In the human embryo, the first site of blood formation is the yolk sac. Later
in embryonic life, the liver becomes the most important red blood
cell-forming organ, but it is soon succeeded by the bone marrow, which in
adult life is the only source of both red blood cells and the granulocytes.
The bone marrow is the soft fatty tissue inside bone cavities. In the human
adult, the bone marrow produces all of the red blood cells, 60–70 percent
of the white cells (i.e., the granulocytes), and all of the platelets.
For white blood cells such as B cells and T cells, they are produced in bone
marrow, B cells will mature in bone marrow while T cells produced in
thymus.
The platelets, which are small cellular fragments rather than complete cells,
are formed from bits of the cytoplasm of the giant cells (megakaryocytes) of
the bone marrow.
Immature blood cells are also called blasts. Some blasts stay in the marrow
to mature. Others travel to other parts of the body to develop into mature,
functioning blood cells.

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