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DDRC SRL DIAGNOSTICS PRIVATE LIMITED
Building No.IV/748 B,B1 & B2 Kunnumbhagam P.O.
Chirakkadavu Panchayath,Kanjirapally, Kottayam - 686 507
Mail: kanjirappally@ddrcsrl.com , Phone : 9496005137
CIN:U85190MH2006PTC161480
Notes:
Test : LFT Sample : Serum Method : Diazo method for Bilirubin total and direct, IFCC without P5P for AST and ALT,IFCC for Alkaline phosphatase ,
Biuret method for protein total , BCG method for albumin and Calculation for globulin and A/G ratio.
Liver function tests are groups of blood tests that give information about the state of liver. These tests include , albumin, bilirubin (Total and direct) ,AST
or SGOT , ALT or SGPT , ALP , & Total protein are useful bio markers of liver injury in a patient with some degree of intact liver function.Most liver
diseases cause only mild symptoms initially, but these diseases must be detected early. Hepatic (liver) involvement in some diseases can be of crucial
importance. These tests are useful in the evaluation and management of patients with hepatic dysfunction. These tests can be used to detect the
presence of liver disease, distinguish among different types of liver disorders, gauge the extent of known liver damage, and follow the response to
treatment. Some or all of these measurements are also carried out (usually about twice a year for routine cases) on those individuals taking certain
medications, such as anticonvulsants, to ensure the medications are not damaging the person's liver.
According to the NCEP guidelines, the following are targets for treatment, Total Cholesterol, Total Triglycerides, LDL Cholesterol and HDL Cholesterol.
VLDL Cholesterol can be calculated as either (TC-HDL-LDL) or as( TG/5). A very large difference between the two values indicates the presence of IDL
and/or other lipoproteins like Lp(a) necessitating further investigation.
Method:
SILGY ROY
Lab Technician
Dept Of Biochemistry
DDRC SRL,Kanjirappally ,Mob:9496005137
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DDRC SRL DIAGNOSTICS PRIVATE LIMITED
Building No.IV/748 B,B1 & B2 Kunnumbhagam P.O.
Chirakkadavu Panchayath,Kanjirapally, Kottayam - 686 507
Mail: kanjirappally@ddrcsrl.com , Phone : 9496005137
CIN:U85190MH2006PTC161480
DEPARTMENT OF HORMONES
Notes:
TSH (Thyroid Stimulating Hormone or Thyrotropin) is produced by Anterior pituitary in response to its stimulation by TRH (Thyrotropin Releasing
Hormone) released from hypothalamus.TSH and TRH releases are regulated by Thyroid hormones through a feedback mechanism.
There are several causes that can lead to Thyroid gland dysfunction or dysregulation which eventualy results in Hyperthyroidism or
Hypothyroidism.Based on the thyroid hormones and TSH levels it can be classified as subclinical,primary or central.
Apart from this,certain other conditions can also leads to diagnostic confusions in the interpretation of a Thyroid function test, and they are Pregnancy,
Levothyroxine therapy, certain other drug therapy,assay interference, alterations in thyroid hormone binding protein's concentration and its binding
capacity, conditions of non-thyroidal illness and certain genetic conditions. TSH secretion exhibits a diurinal pattern , so its advisable to check it during
morning.
Measurement of TSH alone may be misleading , in conditions like Recent treatment for thyrotoxicosis ,TSH-assay interference,Central
hypothyroidism,TSH-secreting pituitary adenoma, Resistance to Thyroid hormone,and Disorders of thyroid hormone transport or metabolism.
TSH receptor present in Thyroid gland can be stimulated or inhibited by auto-antibodies produced during autoimmune thyroid disorders, which can lead
to functional abnormalities of thyroid gland.
The American Thyroid Association determined that only TSH assays with third generation functional sensitivity (sensitivity=0.01mIU/L) are sufficient for
use as screening tests for hyperthyroidism;their recommendation is consistent with the National Academy of Clinical Biochemistry Laboratory Medicine
Practice Guideline for assessment of thyroid function.
Method: CLIA
PRASEEDA S NAIR
Msc. BIOCHEMISTRY
DEPT. OF HORMONES
OPP. MCH , KOTTAYAM ,Tel:-9496005056
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