COMMONWEALTH HIGH SCHOOL

Science and Technology

SY 2020-2021

Name : ___________________________________ Date : _____________________

Grade and Section: _________________________ Teacher : __________________

Science 10

Quarter 3: Living Things Week 4

Most Essential Learning Competences:

Activity Sheet on Protein Synthesis

Activity 4b
DECODING DNA SEGMENT

Objectives:

● Apply the concept of protein synthesis through the amino acids coded for the mRNA
using the genetic code

Materials

● Black pen and coloring pens

● Base template
● Decoding DNA Segment Chart

Procedures:
1. Study the given scenario (see attached activity) and study the profile of the suspects and
additional information.
2. Using your knowledge about DNA and RNA base-pairing, decode the DNA sample in order to
identify the sequence of amino acids. Use the amino acid identifier chart as your reference.
3. Compare the sequence of amino acids (proteins) to the profile of the suspects and additional
information given in order to determine the corresponding traits.
4. Name the culprit using data or information you got.
5. Using the pencil and crayons make a cartographic sketch of the suspect.

Draw the possible appearance of the culprit.

An intruder razed the science laboratory of a Junior High School. The school is in chaos. The
school administrators and teachers demanded to know the culprit. They have to identify the culprit and
do it fast. They had three suspects namely Rudy Tee, Van Go and Rambo Tan. As a forensic expert,
your mission is to identify the intruder using the profile of the suspects and other information taken from
the laboratory:

newton’s lab 2017 commonwealth high school

THE PROFILE OF THE SUSPECTS:

Rudy Tee Van Go Rambo Tan

 Flunked physics class  Suspended for a
three times  His investigative project week by Disciplinary
 with long nose/pointed is about the potential Committee for
nose applications of nuclear in repeated tardiness.
 oval eyes generating energy  Oval eyes
 full lips  short nose/flat nose  Attached earlobe
 attached ear lobe  chinky eyes  Wavy hair
 straight hair  free earlobe  Short nose/flat nose
 curly hair
 full lips

Additional Information: Below are the specific amino acid sequence for specific trait.

1. Nose

● Short : phe-lys
● Long : leu-lys
4. Ear attachment
2. Shape of eyes
● Free earlobe : thr-tyr-ser
● oval : val-ala-ala ● Attached : leu-arg-gly
● chinky : val-ala-val
5. Type of hair
3. Lips
● Straight : lys-glu
● Full lips : phe-glu-ala ● Wavy : phe-ala
● Harelip : phe-lys-ala ● Curl : glu-phe

SUSPECT: TAC-AAA-TTT-ATC-TAC-AAA-CTT-CGT-ATC-TAC-CAT-CGT-CAT-ATT-TAC-
TGG-ATA-TCG-ATC-TAC-CTT-AAA-ATC

Complementary base pairs:

DNA is represented by nitrogen bases that are read in groups of threes. To decode, use
the DNA as a blueprint to produce mRNA. Then use the mRNA as a blueprint to produce the
linear sequence of tRNA. A specific nitrogen base in the DNA pairs up with a specific nitrogen
base in the mRNA, and a specific nitrogen base in the mRNA pairs up with a specific nitrogen
base in the tRNA.

newton’s lab 2017 commonwealth high school

Characteristics and traits of the suspect based on the DNA code.

1. Nose :________________

2. Eyes :________________

3. Lips :________________

4. Ear Attachment :________________

5. Type of Hair :________________

Breaking the Code: Complete the data below

DNA triplet code mRNA tRNA Amino Acid

1. TAC AUG UAC Met (start)

2. AAA

3. TTT

4. ATC AUC

5. TAC Stop

6. AAA UUU

7. CTT

8. CGT

9. ATC AUC

10. TAC

11. CAT

12. CGT Ala

13. CAT GUA

14. ATT

15.TAC

16. TGG UGG

17. ATA

18. TCG

19. ATC

20. TAC

21. CTT GAA

22. AAA

23. ATC AUC STOP

newton’s lab 2017 commonwealth high school

 ____________________________________________
Name and cartographic sketch of the suspect

Q1. What amino acids sequences did you get upon decoding the genes?
nose : _______________________________
shape of eyes : __________________________________________
lips : ___________________________________________
ear attachment : ___________________________________________
type of hair : ___________________________________________

Q2. What are the traits of the culprit based on your data?

___________________________________________________________________________
___________________________________________________________________________

Q3. Who among the suspects matches with the sequence of amino acids (proteins) you got?
_______________________________________________________________________________
_______________________________________________________________________

newton’s lab 2017 commonwealth high school

Prepared by:

RONNIE L. CAAYA
Teacher III

newton’s lab 2017 commonwealth high school