Name of Drug Doctor’s Mechanism of Indication Contraindicatio Side effects Adverse Nursing

Order Action n Reaction Consideration

Intravenous 2 g/kg of Primary Patients who  Cough  Headach When
gamma globulin IVIG / IVIg interacts Immunodeficiency develop aseptic  cough e administering
(IVIG) 12 hours with a number of meningitis with producing  flushing, IVIG, an
q5days different  for the IVIG may have mucus  malaise, infusion nurse
CLASSIFICATIO components of treatment of increased cell  difficulty  chest must assess
N: the immune primary count and breathing tightness, the patient’s
Protein Based system, including immunodefic protein in their  fever  fever, health history
Therapies cytokines, iency in CSF but their  headache  chills, and perform a
complement, Fc adult and culture is  pain or risk
 myalgia,
Brand name: receptors and pediatric typically tenderness assessment
 fatigue,
Flebogamma several cell patients negative for around the prior to each
surface infectious  dyspnea, infusion.
 in eyes and
Generic Name: immunocompete microorganisms.  back Special
combination cheekbone
Human nt molecules. IVIG is pain, consideration
with hyaluro s
immunoglobulin IVIg also impacts nidase contraindicated  nausea, needs to be
 pale skin  vomiting,
G different effector (human in patients with taken in regard
 stuffy  diarrhea,
cells of the recombinant known to the patient’s
or runny  blood
Administration: immune system ) for the hypersensitivity history of
nose pressure
January 13, 2021 (B and T treatment of to IVIG. exposure to
lymphocytes,  tightness changes, IVIG. For
primary
Date dendritic cells, of the  tachycard instance,
immunodefic
Discontinued: etc.) and chest ia, patients are
iency in
January 18, 2021 regulates a wide  trouble  anaphyla categorized in
adults
range of genes. breathing ctic the following
Its main  unusual reactions, manner:
Immune
mechanism of bleeding or especiall • IVIG naïve:
Thrombocytopenic
actions are bruising y in IgA- patients who
Purpura (ITP)
believed to be  unusual deficient have never
Fc-dependent tiredness patients. received IVIG
 for the
and F(ab')2- or • IVIG initial
treatment of
dependent. IVIg weakness infusions:
acute or
competitively chronic patients who
blocks gamma immune have received
Fc receptors, thrombocyto
preventing the penic IVIG but may
binding and purpura in have changed
ingestion of adult and brands or have
phagocytes and not received
suppressing pediatric therapy within
platelet patients six weeks
depletion. IVIg • IVIG
contains a Chronic subsequent
number of Inflammatory infusions:
different Demyelinating patients who
antobodies, Polyneuropathy will receive
which prevent (CIDP) therapy after
infection by they have
attaching to the  for the received their
surface of treatment of first dose from
invading CIDP in a new brand,
pathogens and adult after the first
aiding in their patients lifetime dose or
disposal before after having
they can infect Multifocal Motor received the
cells. Antibodies Neuropathy (MMN) same drug
remove within a six-
pathogens via week time
 for
complement frame
maintenance
activation, (subsequent
therapy to
agglutination or infusions are
improve
precipitation, also defined as
muscle
pathogen infusions that
strength and
receptor are well-
disability in
blocking, tolerated
adult
macrophage without a
patients with
“tagging” or reaction or
MMN
neutralization significant
(via binding) of change in vital
pathogen toxins. Prophylaxis of signs
Intact IVIg and Bacterial Infection
F(ab′)2
fragments of IVIg  for the
can also prevention of
neutralize the bacterial
activity of various infections in
autoantibodies. patients with
hypogamma
By triggering the
production of globulinemia
interleukin-1 and/or B-cell
receptor chronic
antagonist, IVIg lymphocytic
modulates of the leukemia
production of
cytokines and Coronary Artery
cytokine Aneurysm
antagonists. It Associated With
also prevents the Kawasaki
generation of the Syndrome
C5b-9
membrane  for the
attack complex prevention of
and subsequent coronary
complement- artery
mediated tissue aneurysms
damage by in pediatric
binding active patients with
complement Kawasaki
components. syndrome

Dermatomyositis

 for the
treatment of
dermatomyo
sitis in adult
patients14
Name of Drug Doctor’s Mechanism Indication Contraindication Side effects Adverse Nursing
Order of Action Reaction Consideration
Aspirin 300mg 1 Unknown. >Mild pain or >Contraindicated  dyspepsia, EENT: tinnitus, >For
tab TID Thought to fever, Kawasaki to patient’s  epigastric hearing loss inflammatory
CLASSIFICATION: P.O. produce3 syndrome hypersensitivity to discomfort, Hematologic: conditions,
Analgesics (Non- analgesia by (mucocutaneou drug and in those  heartburn, leukopenia, rheumatic
Opioid) & blocking pain s lymph node with NSAID – and thrombocytopenia, fever and
Antipyretics / CNS impulses by syndrome) induced  nausea.  prolonged thrombosis,
drug inhibiting sensitivity bleeding time. give aspirin on
synthesis of reactions, G6PD GI: nausea, GI a schedule
Brand Name: prostaglandin deficiency, or distress, occult rather than
Bayer aspirin in the CNS or bleeding bleeding, P.R.N.
300mg of other disorders such as dyspepsia, GI >Because
substances hemophilia. bleeding. enteric-coated
Generic Name: that sensitize Hepatic: hepatitis and sustained
Aspirin pain Skin: rash, release tablets
receptors to bruising, urticarial are slowly
Administration: stimulation. Other: absorbed, they
January 13, 2021 The drug angioedema, aren’t suitable
may relieve hypersensitivity for rapid relief
Date Discontinued: fever through reactions of acute pain,
Up to 6 weeks central action fever or
after in the inflammation.
discharge( hypothalamic They cause
3mg/kg/day) heat- less GI
regulating bleeding and
center and may be better
exert its anti- suited for long-
inflammatory term therapy;
effect by such as
synthesis of treatment of
inhibiting arthritis.
prostaglandin
and that of
other
mediators of
the
inflammatory
response as
 well.

Name of Drug Doctor’s Mechanism Indication Contraindication Side effects Adverse Nursing
 Order of Action Reaction Consideration
Paracetamol 120MG Thought to >Mild pain >Contraindicated  Diarrhea Hematologic: >Many OTC
ORAL q6h produce3 or fever to patient’s  increased hemolytic and prescription
CLASSIFICATION: PRN analgesia by -Headache, hypersensitivity to sweating anemia, products
Analgesics (Non- blocking pain fever drugs.  loss of appetite neutropenia, contain
Opioid) & impulses by associated  nausea or vomitin leucopenia, acetaminophen;
Antipyretics inhibiting with colds. >Use cautiously g pancytopenia be aware of tins
synthesis of in patients with  stomach cramps Hepatic: when
Brand Name: prostaglandin long term alcohol or pain jaundice calculating total
Tempra 1 in the CNS or use because  swelling, pain, or Metabolic: daily dose.
of other therapeutic doses tenderness in the hypoglycemia >Use liquid
Generic Name: substances cause upper abdomen or Skin: rash form for
Acetaminophen that sensitize hepatotoxicity in stomach area urticaria children and
Drops pain receptors these patients patients who
to stimulation. have difficulty
Administration: The drug may swallowing.
January 12, 2021 relieve fever >In children,
through don’t exceed
Date discontinued: central action five doses in
January 13, 2021 in the 24hrs.
hypothalamic
heat-
regulating
center.

Name of Drug Doctor’s Mechanism Indication Contraindication Side effects Adverse Nursing
 Order of Action Reaction Consideration
Ampicillin 250MG 1 Inhibits cell- >Fever/infections >Contraindicated eosinophilia CNS: lethargy, >Before giving
tab q6 P.O wall synthesis >Skin and skin- in patient’s and skin rash hallucinations, drug, ask
CLASSIFICATION: during structure hypersensitivity to seizures, patient about
Anti-ineffectives / bacterial infections. drug or other anxiety, allergic
Penicillins multiplication. penicillin. confusion, reactions to
>Use cautiously in agitation, pennicilin. A
Brand Name: patients with other depression, negative
Omnipen drug allergies. dizziness, history of
Because of fatigue penicillin
Generic name: possible cross- CV: vein allergy is no
Ampicillin sensitivity, and in irritation, guarantee
those with thrombophlebitis. against a future
Administration: mononucleosis, GI: nausea, allergic
January 13, 2021 because of high vomiting, reaction.
risk of diarrhea > Obtain
Date discontinued: maculopapular GU: interstitial specimen for
January 20, 2021 rash. nephritis, culture and
nephropathy, sensitivity tests
vaginitis before giving
Skin: pain at first dose.
injection site Therapy may
Other: begin pending
hypersensitivity results.
reactions
Name of Drug Doctor’s Mechanism Indication Contraindication Side effects Adverse Nursing
Order of Action Reaction Consideration
Corticosteroid 7mg/kg/day The activation For the -Hypersensitivity to Not for IV
Celestone of a group of reduction in betamethasone  confusion,  hives, administration
Drug
syrup Orally proteins the chance Idiopathic  frequent  difficulty Use caution in
Class: Corticosteroids
known as of future thrombocytopenia cirrhosis, ocular
lipocortins, heart purpura urges to breathing, herpes simplex,
Brand which in turn problems -Live or live, HTN,
inhibit as well as attenuated urinate,  swelling of diverticulitis,
Name: Celestone
Syrup phospholipase the effect vaccines, when  sleepiness, your face, hypothyroidism,
A2, on the immunosuppressive myasthenia
responsible for duration of doses of  increased lips, gravi, PUD,
Generic the synthesis fever, signs corticosteroids osteoporosis,
Name: betamethasone of leukotrienes of infection required thirst, tongue, or ulcerative
from in the blood .  hunger, throat, colitis,
Administration: arachidonic and the psychotic
January 13, 2021 acid, thus number of  trembling,  wheezing, tendencies,
blocking the days spent untreated
Date inflammatory in hospital.  dizziness,  chest pain systemic
discontinued:January cascade.  weakness, or infections, renal
16, 2021 insufficiency,
 fatigue, pressure, pregnancy
 fast  fever, May cause
heartbeat,  seizure, adrenal
suppresion in
 muscle pain,  blue skin patients
receiving high
 muscle color, doses for
cramps,  cough, prolonged
periods of time
 acne,  fever, and
Prolonged use
 slow wound  chills
of
healing, corticosteroids
may increase
 increased incidence of
secondary
hair growth,
infection
 stretch
Monitor closely
 patients with
marks, latent
 fever, tuberculosis or
tuberculin
 chills, reactivity, if
corticosteroid
 cough, therapy
 sore throat, necessary;
reactivation of
 mood the disease
may occur
changes,
 spotting or a Killed or
inactivated
skipped vaccines may
be
period, administered;
 vision however, the
response to
changes, such vaccines
cannot be
 blurred predicted
vision,
 headaches,
 weight gain,
 sweating,
 restlessness
, and
 nausea

Name of Drug Doctor’s Mechanis Indication Contraindication Side effects Adverse Nursing
 Order m of Reaction Consideratio
Action n
Heparin 20 Bolus Inhibits  -Prevention Hypersensitivity  Abdominal or  Loss of hair -Adjust dose
Heparin thrombus and treatment to heparin; severe stomach pain or  Hemorrhage according to
Drug 0.7U/mL and clot of venous thrombocytopenia swelling ; bruising; coagulation
class: Anticoagul Subcutaneou formation thrombosis and ; uncontrolled  back pain or thrombocyto test results
ant, s q4 by blocking pulmonary bleeding; any backaches penia; performed just
the embolism patient who  bleeding from elevated before
Brand Name: conversion · Treatment of cannot be the gums when AST, ALT injection (30
heparin sodium of atrial fibrillation monitored brushing teeth levels, min before
injection prothrombin with regularly with  blood in the urine hyperkalemi each
to thrombin embolization blood coagulation  constipation a intermittent
Administration: and · Diagnosis tests; labor and  coughing up  Chills, fever, dose or q 4 hr
January 13, 2021 fibrinogen and treatment immediate blood urticaria, if continuous
to fibrin, the of DIC postpartum asthma IV dose).
 dizziness
Date final steps · Prevention of period; women  Osteoporosi Therapeutic
 headaches,
discontinued:Jan in the clotting in older than 60 yr s, range APTT:
severe or
uary 18, 2021 clotting blood samples are at high risk for suppression 1.5–2.5 times
continuing
process. and heparin hemorrhaging; of renal control.
lock sets and dysbetalipoprotei  heavy bleeding · Use heparin
or oozing from function
during dialysis nemia; recent (long-term, lock needle to
procedures surgery or injury. cuts or wounds avoid
 joint pain, high-dose
· Unlabeled therapy) repeated
uses: adjunct stiffness, or injections.
in therapy of swelling · Give deep
coronary  menstrual SC injections;
occlusion with bleeding, do not give
acute MI, unexpected or heparin by IM
prevention of unusually heavy injection.
left ventricular  unexplained · Do not give
thrombi and bruising or IM injections
CVA post-MI, purplish areas on to patients on
prevention of the skin heparin
cerebral  unexplained nos therapy
thrombosis in ebleeds (heparin
the evolving  vomiting of blood predisposes
stroke or material that to hematoma
looks like coffee formation).
grounds · Apply
pressure to all
injection sites
after needle is
withdrawn;
inspect
injection sites
for signs of
hematoma; do
not massage
injection sites.
· Mix well
when adding
heparin to IV
infusion.
· Do not add
heparin to
infusion lines
of other drugs,
and do not
piggyback
other drugs
into heparin
line. If this
must be done,
ensure drug
compatibility.
· Provide for
safety
measures
(electric razor,
soft
toothbrush) to
prevent injury
from bleeding.
· Check for
signs of
bleeding;
monitor blood
tests.