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Problem 1 Scenario 1
Case of Willy
Willy, a 35 year old male came to the ER hospital where you are working as a staff nurse. He
came for admission with complaints of low grade fever and body malaise for 10 days. The
physician on duty evaluated his history and did not reveal any significant medical conditions.
Initial assessment shows the patient’s complete blood count is elevated with total white blood
cell (WBC) count of 100,000 cells/μL with 75% blast cells.
On the 2nd day of confinement there was an abrupt increase in Willy’s temperature to
39.5degrees centigrade. He also developed small, shallow oral ulcers, which tested negative for
cytomegalovirus (CMV) and for herpes simplex virus (HSV) by polymerase chain reaction
(PCR). Willy was then prescribed cefepime for neutropenic fever. He developed diarrhea, losing
around 700 mL per day. A stool examination did not detect the presence of red blood cells, WBC
or pathogens like bacteria or fungi. A PCR test further confirmed that there was no Clostridium
difficile present in the stool samples. However, blood cultures detected Enterococcus faecium.
His antibiotic regimen was subsequently switched to treatment with imipenem and vancomycin.
2 weeks later: