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JULY 2, 2021
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In a discovery that challenges long-held dogma NASA’s Self-
in biology, researchers show that mammalian
cells can convert RNA sequences back into Driving
DNA, a feat more common in viruses than
eukaryotic cells. Perseverance
Cells contain machinery that duplicates DNA into Mars Rover
a new set that goes into a newly formed cell. That
same class of machines, called polymerases, also “Takes the
build RNA messages, which are like notes copied
from the central DNA repository of recipes, so they Wheel”
can be read more efficiently into proteins. But
polymerases were thought to only work in one Perseverance’s First
direction DNA into DNA or RNA. This prevents Autonav Drive:
RNA messages from being rewritten back into the Perseverance relies on
master recipe book of genomic DNA. Now, Thomas left and right navigation
Jefferson University researchers provide the first
cameras. The view seen
evidence that RNA segments can be written back
here combines the
into DNA, which potentially challenges the central
perspective of two
dogma in biology and could have wide
cameras rover during
implications affecting many fields of biology.
the…
“This work opens the door to many other studies
that will help us understand the significance of READ MORE
having a mechanism for converting RNA messages
into DNA in our own cells,” says Richard
Pomerantz, PhD, associate professor of
JULY 2,
biochemistry and molecular biology at Thomas
2021
Jefferson University. “The reality that a human
Skin
polymerase can do this with high efficiency, raises
Reactio
many questions.” For example, this finding ns
suggests that RNA messages can be used as After
templates for repairing or re-writing genomic COVID-
DNA. 19
Vaccin
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The work was published June 11th, 2021, in the ation: Rare, Usually Don’t Recur
journal Science Advances. After Second Dose
Hubble
In a series of elegant experiments, the researchers Space
tested polymerase theta against the reverse Telesco
transcriptase from HIV, which is one of the best pe’s
studied of its kind. They showed that polymerase Comput
theta was capable of converting RNA messages er Is
into DNA, which it did as well as HIV reverse Still
Down –
transcriptase, and that it actually did a better job
Here’s
than when duplicating DNA to DNA. Polymerase What
theta was more efficient and introduced fewer NASA
errors when using an RNA template to write new Is
DNA messages, than when duplicating DNA into Trying
DNA, suggesting that this function could be its Now
primary purpose in the cell.
JULY 1,
The group collaborated with Dr. Xiaojiang S. 2021
Chen’s lab at USC and used x-ray crystallography
Winner
to define the structure and found that this Takes
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molecule was able to change shape in order to All: Galaxies Headed for
accommodate the more bulky RNA molecule — a Collision on Intergalactic “Road
feat unique among polymerases. of Matter”
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Wrong? New Their Own Workings of Predicts How Diseases JPL Mars
Research Destiny – the Enzyme Well People
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Secret Behind Their Own the First Time Ingrained Planck Institute Medicine
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Search for Cells
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91 COMMENTS
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pm | Reply
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welcome here.
commenter |
June 13, 2021
at 1:38 pm |
Reply
Where is his/her
comment wrong?
Jim
Jameson
| June 16,
2021 at 6:57 am |
They’re argument is
akin to jumping off
a cliff. The ground
is the so-called
“killer” (bacterial
pneumonia) but I
don’t think a
reasonable person
would advise the
jump. Get rid of the
jump (Spanish Flu)
the ground is
innocuous.
TW | June 15,
2021 at 1:27 pm
| Reply
IScherr | June
15, 2021 at
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2:59 pm | Reply
R P | June 16,
2021 at 7:17 am
| Reply
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https://www.irishtimes.com
/news/world/europe/german-
scientists-claim-to-have-solved-
covid-vaccine-blood-clot-puzzle-
1.4576752?mode=amp
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Babu G. Ranganathan*
(B.A. Bible/Biology)
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I love this
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https://www.sciencedirect.com/science
/article/pii/S1201971221003647
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Reply
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Wont*
Sorry Fran t-9 its early and it wouldn’t let
me edit comment. Sorry.
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pm | Reply
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