● The capacity of the blood to transport oxygen may be inhibited at high concentrations, which

can result in symptoms such as headache, weariness, and dizziness, as well as a bluish
coloration to the skin and lips (methemoglobinemia).
● When levels are high enough, they may make breathing difficult, potentially lead to collapse
and death.
● When exposed to high levels, people may experience headaches, disorientation, seizures, and
even coma.

Chronic Effects:
The following are the chronic (long-term) health effects that may occur after the exposure to
phenacetin:
● Phenacetin has been shown to have carcinogenic potential in human studies.
● Some people may have an allergic reaction to phenacetin that shows up as a rash and itching.
● It is possible for very high or frequent exposure to kill red blood cells, which would result in
a low blood count (anemia).
● There is some evidence that phenacetin is harmful to the kidneys and liver.

Reference/s:
Phenacetin. (n.d.). New Jersey Department of Health and Senior Services Hazardous Substance
Fact Sheet. Retrieved May 17, 2022, from
https://nj.gov/health/eoh/rtkweb/documents/fs/1483.pdf

2. Name the medical test used to determine whether the person have been exposed to phenacetin.
The following medical tests are suggested for persons who are often or possibly highly
exposed to phenacetin:
● Liver and kidney function test.
● Blood methemoglobin level test.
● Complete blood count test.
● Evaluation by a qualified allergist, including careful exposure history and special testing,
may help diagnose skin allergy.