Professional Documents
Culture Documents
Reckoner for
Medical Representative
Training
Dear Students,
Here is something which will be your constant companion not only during
the entire period of Training but also for your future use during interviews.
This is not only a book, it is also a guide which can enhance your
knowledge and help you to become a confident and successful
candidate facing the interview.
We know that this will be a useful tool and hope that you will be putting it
into use diligently.
FROM CARREOGRAPH
TRAINING DESK
INDEX
SECTION B :
CARREOGRAPH
8. Pronunciation .............................................................................. 8
9. The Human Body ......................................................................... 9
10. Cytology ....................................................................................... 10
11. Cell Division ................................................................................. 11
12. Musculoskeletal System ............................................................. 12 - 13
13. Note ............................................................................................. 14
14. Digestive System ......................................................................... 15 - 21
15. Note ........................................................................... 22
16. Metabolism .................................................................................. 23
17. Diabetes ....................................................................................... 24 - 25
18. Expansions of Abbreviation ......................................................... 26 - 27
19. Cardiovascular System ................................................................ 28 - 34
20. Note ............................................................................................. 35
21. Respiratory System ..................................................................... 36 - 38
22. Note ............................................................................................. 39
23. Biological Classification of Pathogenic Micro Organisms ............ 40 -41
24. Classification of Antimicrobial Drugs / Pharmacology 42 - 43
25. .................. 44 - 45
26. Nervous System .......................................................................... 46
27. Note ............................................................................................. 47 - 48
28. Urinary System ............................................................................ 49
29. Note ............................................................................................. 50 - 52
30. Endocrine ..................................................................................... 53 - 54
31. Reproductive System ................................................................... 55
32. Note ............................................................................................. 56 - 59
33. The Skin ..................................................................................... 60
34. Eye ............................................................................................... 61
35. Teeth ............................................................................................ 62
36. Detailing Story - Memorization ..................................................... 63 - 64
Ingredients of Ayurvedic Medicines..............................................
SECTION - A
1
2. Boys should wear formal dress (trousers, shirt, shoes) and cleanly shaved during
training. Girl candidates should be in churidar or western formals (trousers,
ladies shirt, formal shoes) and with minimum jewellery.
3. Students should carry Bio-Data with passport size photograph during training
period everyday while attending classes. Boys must carry one tie, should know
CARREOGRAPH
how to knot the tie.
4. In addition to the campus and other interviews arranged by us, students should
also go through “appointment section” of different newspapers and apply to
pharmaceutical companies wherever eligible after the Mock interview.
7. Mobile phones should be switched off inside the training room and
interview campus.
10. Regular attendance is necessary throughout the training and that will be checked
before sending for Co's interview.
11. Students (Kolkata) should not park their bike on the tram track (Restriction
from Kolkata Police).
12. Students should not bring any gifts / flowers / sweets or any food packets, for
any reason to CARREOGRAPH. Your job and career in the pharma industry is
reatest reward for us.
2
GUIDELINES
FOR LADY CANDIDATES
DRESS CODE:
CARREOGRAPH
colour dupatta.
To wear light makeup (no loud colours to be used for lipstick or nail
polish) and minimum jewellery.
INTERVIEW GUIDELINES:
1. Take any topic / story / newspaper report and practice these in english before a
mirror repeatedly to improve your english communication.
3. Listen hourly TV news (DD news, NDTV news, Times Now, Republic TV
etc.) in english for correct pronunciation.
CARREOGRAPH
Spend three hours every day for all the above.
On the day of Saraswati Puja all present & ex-students are cordially invited at
the institute to attend the Puja.
4
Sample Biodata
BIODATA BIODATA
Completed B.A under Calcutta University with 55% in the year Completed B.A under Calcutta University with 55% in the year 2015.
CARREOGRA PH
2015. Passed Higher Secondary Examination under W.B.C.H.S.E Passed Higher Secondary Examination under W.B.C.H.S.E with
with 41% in the year 2012. 41% in the year 2012.
Passed Madhyamik Examination under W.B.B.S.E with 49% in Passed Madhyamik Examination under W.B.B.S.E with 49% in
the year 2010. the year 2010.
OTHERS: OTHERS:
EXPERIENCE : Worked with Bhandari Automobiles as EXPERIENCE : Worked with Bhandari Automobiles as
Sales Representative for 2 years Sales Representative for 2 years
EXTRA CURRICULAR ACTIVITY : Played Cricket under C.A.B. EXTRA CURRICULAR ACTIVITY : Played Cricket under C.A.B.
AREAS OF INTEREST : Gardening, Listening to Music AREAS OF INTEREST : Gardening, Listening to Music
LANGUAGES KNOWN : English, Bengali, Hindi LANGUAGES KNOWN : English, Bengali, Hindi
I have a two wheeler & my licence no is I have a two wheeler & my licence no. Is
Date: Date:
Place: (DEBASISH SEN) (DEBASISH SEN)
Place:
BIODATA BIODATA
FATHER’S NAME
RESIDENTIAL ADDRESS : MR. PERSONAL
: INFORMATION:
PHONE NO.
: : Mr. Gautam Sen
E-MAIL ID
: FATHER’S NAME : 02/06/1992
NATIONALITY
: INDIAN DATE OF BIRTH : Indian
RELIGION
: NATIONALITY : Hinduism
MARITAL STATUS
: RELIGION : Single
GENDER
: MARITAL STATUS : Male
GENDER
ACADEMIC QUALIFICATION
ACADEMIC QUALIFICATION:
NAME OF UNIVERSITY / YEAR OF Completed B.A under Calcutta University with 55% in the year 2015. Passed Higher Secondary
% OF MARKS
EXAMINATION COUNCIL / BOARD PASSING Examination under W.B.C.H.S.E with 41% in the year 2012.
B.SC / B.COM / BA Passed Madhyamik Examination under W.B.B.S.E with 49% in the year 2010.
Date:
Place: Date:
(Print own Name in Capital Letter) (DEBASISH SEN)
Place:
5
IMPORTANCE OF MOBILITY
Dear Student,
CARREOGRAPH
restrict in the process of our selection for interview as well as
selection by the companies.
(Training Desk)
6
CARREOGRAPH
the job of a Medical Representative for which two-wheeler is required.
Basic requirements for maintaining a two-wheeler;
1. Driving
license.
2. Smart card, Insurance paper & emission certificate is
mandatory.
3. If a candidate's father or any close relative owns a two wheeler, then the
candidate
can use the same two- wheeler with an authorization letter from the owner. In such
cases, the candidate has to go to Court & make the authorization letter in stamp
paper by any Notary or government authorized lawyer.
4. If a candidate wants to purchase a second hand two wheeler from anybody, he/ she
has to go to the Regional Transport Office(RTO) with the owner of the two
wheeler & fill in form 29-30 by which he/she can transfer the two-wheeler in his
/her name.
5. It is important to note that one can purchase a two-wheeler any time but it is time
consuming to get a Driving license & Smart card. So it is suggested that
candidates who does not have a driving license should immediately apply for the
same.
Proper dress code as per motor vehicles act should be maintained while driving a
two-wheeler .Wearing a helmet is mandatory for a safe drive.
7
CARREOGRAPH
2. VOXX 10 90 100 70 30
3. FINEE 25 75 100 35 65
4. ZIP 10 60 70 55 15
PRONUNCIATION
1
Pharmacopoeia -
- 20
Ischaemia -
2
Therapeutics 21
Retinoblastoma -
- 22
Urticaria -
3
Intravenous 23
- Tachycardia -
24
4
Swelling Rheumatologist -
25
- Bacilli -
5
Subcutaneous 26
Abscess -
- 27
Hemorrhoid -
6
Ointment 28
Cystoscopy -
- 29
Peritoneal -
7
Coccyx 30
- Gigantism -
8
Pneumothorax
CARREOGRAPH
-
9
Homogenized
-
10
Sterilized
-
11
Bradycardia
-
12
Dyspnea
-
13
Rhinitis
-
14
Osteoporosis
-
15
Nephrologist
-
16
Orthopedics
-
17
Hypothyroidism
-
18
Encephalitis
-
19
Neuropathy
9
Farma - logist Ba - si - ly
kopia Thera Ab - sess
- pu - tics Hemo - roid
Intra - ve - Cis - tos - copy
nus Soel - Peri - to - nial
ling Jai - gan - tism
Sub kuta -
neous Oint
- ment
Kok - cyx
Neumo -
thorax
Homo - ge -
nized Ste -
ri - lized
Bra - di -
kardia
Disp -
nea
Ri - ni - tis
Os - tio -
poro - sis
Nef - ro -
logist Ortho
- pe - dics
Haipo - thai - roi
- dism En - ke -
fa - litis
Nuro -
pathy
Is - ke
- mia
Reti - no - blas -
toma Arti - ka -
ria
Taki - kar - dia
Ru - ma - to -
10
The body as a whole is built up round the bony framework of the skeleton and
consists of three main parts:
CYTOLOGY
Cytology is the branch of biology which deals with the study of structure and function of
cell. Cell is the basic structural and functional unit of living body.
Three main components of cells :
1. Plasma Membrane / Cell Membrane - The semi permeable membrane that
separates the interior of all cells from outside environment and protects
the cell.
2. Nucleus - Controls activities of the cell.
3. Cytoplasm - Surrounds the nucleus and carries out the activities
RREOG
Determined by the nucleus.
Nucleus and Cytoplasm together is called Protoplasm, the living substance of
the Cell.
The structure of the cell
CELL MEMBRANE: It is made up of lipids and proteins and gives shape and
protection to the cell and is also selectively permeable.
CYTOPLASM: A jelly like substance that fills up the cell and is surrounded by the cell
membrane.
NUCLEUS: It is the dense portion of the cell housing the genetic material that is
chromosome.
Gene: The hereditary unit of life, it is a unit of DNA located on the chromosome which
passes information from parent to offspring.
Mitochondria: Called the power house of the cell, it is where glucose is brokendown
releasing energy stored in the form of ATP.
12
CELL DIVISION
Function of Cell
Cell membrane is permeable to selective substances.
Gives response to external stimuli.
Has the ability to absorb nutrients and excrete waste products.
Has the capacity for growth and repair.
Has the ability to reproduce in Mitosis and Meiosis way.
MITOSIS MEIOSIS
- 2 identical daughter cell with 46 - Daughter cells with 23 chromosomes
chromosomes are formed develop
C
AR
REO
GR
APH
- Takes place in all somatic or body cells - Takes place only in Testes In males
of males and Ovary of females (sperm) and Ovary in females (ovum).
- For growth and repair. - For birth of next generation.
TISSUE: Similar cells put together and performing the same function are called
tissues. There are 5 types of tissues:
EPITHELIAL TISSUE
CONNECTIVE TISSUE
MUSCULAR TISSUE NERVOUS TISSUE
AREOLAR TISSUE
A group of tissues that perform a similar function (or functions) is called an
ORGAN. For e.g Heart, Liver, Lungs, Kidney
Organs when put together as they are engaged in the same type of function, form
SYSTEMS.
MUSCULOSKELETAL SYSTEM
Muscles are responsible for movement and various activities in our body.
REOG
CARDIAC - involuntary in nature and found only in the heart. Cardiac muscles
are controlled by Autonomic Nervous System.
THE SKELETON
SKULL
MANDIBLE
RIBS STERNUM
HUMERUS
ULNA
CARPALS
RADIUS
METACARPALS
PHALANGES
FEMUR
TIBIA
TARSALS FIBULA
PHALANGES METATARSALS
MUSCULOSKELETAL SYSTEM
Longest bone in our body is FEMUR and the smallest bone is STAPES in the middle
ear.
There are 12 pairs of Rib Bones originating from Vertebral Column and attached
With the STERNUM in the front, 10 pairs attached and 2 pairs remain hanging and
also called the Floating Ribs.
Some Bone and Joint diseases:
NOTE
16
DIGESTIVE SYSTEM
The mouth cavity : Teeth ,hard and soft palate ,Tongue ,salivary glands (one pair each
of parotid, sub maxillary and sub lingual)
Function : The food which is taken into the mouth is chewed with teeth and mixed with
saliva ,secretions of salivary glands to render it into a state suitable for swallowing.
Enzyme Salivary - amylase : Converts cooked starch into Maltose.
Pharynx : Acts only for food passage
Oesophagus : -do-
Stomach : A muscular bag just below the
diaphragm at the end of Oesophagus which
retains food for several hours. It has got
4 segments Cardiac Orifice, Fundus, Body & Pylorus.
The Small intestine has millions of tiny finger-like projections called Villi. Function of
Villi is to absorb nutrients (simple food) from small intestine into the blood stream.
Function : Mainly water absorption and excretion of waste products faeces or stool.
The function of the entire system is aided by secretions from largest gland liver (bile)
and mixed gland pancreas (pancreatic juice).
17
DIGESTIVE SYSTEM
Gall Bladder : Also associated with digestive system is the rear shaped gall bladder,
which is a small hollow organ which lies just beneath the liver. It is how that bile is
stored and concentrated before it is released into the small intestine.
What is digestion?
Digestion is a process where complex food molecules are broken down into simple
forms, which can be absorbed and used by the body.
2) Rennin(coagulates milk)
3) Small amount of gastric lipase (fat splitting enzyme)
What is liver?
1) Liver is the largest gland in the body
2) Liver is the head quarters of metabolism
3) Liver is the part of digestive system
DIGESTIVE SYSTEM
What is Metabolism ?
Metabolism involves the biochemical processes through which complex substances
are broken down with liberation of energy(catabolism) and building up of complex
substances from simple ones with the formation of tissue protein (anabolism).
Maintaining the continuing equilibrium (Isobolism).
What is Peristalsis?
Involuntary wave of muscular contraction followed by dilatation starting from
Oesophagus in presence of food effecting easy forward passage of food.
What is Sphinter?
A specialized ring of muscles that surrounds an orifice allowing substance to pass in
the forward direction only.
What is Calorie?
A unit of heat equal to the amount of heat required to raise the temperature of 1 gm of
water through 1º C.
Vitamins :
Group of substances essential for body growth. They do not produce calories but act
as catalysts. We require small amounts. They can't be synthesized in the body but
available in the food we take.
They are of two types. The water soluble group includes vitamin B complex and vitamin
C. The fat soluble group includes vitamin
DIGESTIVE SYSTEM
Minerals:
These are inorganic substances in the diet, required in small amounts, essential for
life. To name major minerals calcium, magnesium, sodium, potassium, phosphorus,
sulphur etc.
Stomach :
The main pancreatic duct meets the common bile duct, the two ducts join together,
dilate into an ampulla (Vater) and open into the 2nd part of duodenum over the summit
of the major duodenal papillae.
20
DIGESTIVE SYSTEM
Function of Bile -
1. Bile emulsifies Fat and Lipase converts the fat into Fatty Acid and Glycerol.
2. For proper absorption of digested fat, the presence of bile salts is necessary. They
act by lowering surface tension. Fatty Acid & Glycerol are absorbed into the villi of
small intestine.
glycerol
Small Succus Alkaline 1. Entero
Intestine Entericus Kinase Liberates Trypsin from Pancreatic fluid
OESOPHAGUS
STOMACH
PANCREAS
PANCREAS
22
CARREOGRAPH
DYSPHAGIA : Difficulty in swallowing.
PROCTITIS : Inflammation of anus or rectum.
STOMATITIS : Inflammation of soft tissue of mouth.
PHARYNGITIS : Inflammation of pharyn
TONSILLITIS : Inflammation of tonsils.
PEPTIC ULCER : Damage in the mucous membrane lining the area of
stomach exposed to acid & pepsin.
HYPERACIDITY : Excessive secretion of hydrochloric acid in stomach.
PERISTALSIS : Wave of contraction & relaxation commonly referred to
the alimentary tract.
SPASM : Sudden violent contraction.
FAECES : Stool, waste product excreted by intestines.
APPENDICITIS : Inflammation of appendix.
DIARRHOEA : Frequently passing of abnormally soft or liquid faeces.
JAUNDICE : Excess of bilirubin in the blood yellowing of the skin or
whites of the eyes.
GASTRITIS : Inflammation in Stomach
DYSPEPSIA : Indigestion
GASTROENTERITIS : Inflammation of stomach & Intestine
IBS : Irritable Bowel Syndrome
PANCREATITIS : Inflammation in Pancreas
23
NOTE
24
METABOLISM
Metabolism starts after absorption and is finished when the end products are
excreted. The chemical changes (1) Synthesis known as ANABOLISM, (2)
breakdown called
CATABOLISM and (3) maintaining equilibrium called ISOBOLISM, comprises total
Metabolism.
CARREOGRAPH
In short: METABOLISM is the term for all the chemical and physical processes
required for life, using absorbed nutrients.
ANABOLISM = When nutrients are used to build compounds and body tissues, this
process is called Anabolism.
CATABOLISM = When compounds and body tissues are broken down, releasing
energy stored as ATP, the process is called Catabolism.
A. NUTRIENTS are :
CATEGORY I (MACRONUTRIENTS)
CARBOHYDRATES.
PROTEINS.
FATS.
CATEGORY II (MICRONUTRIENTS)
VITAMINS.
MINERALS.
B. The ENERGY produced in the body may be measured and expressed
In units of work (Joules) or units of heat (Kilocalories).
BASAL METABOLIC RATE (BMR) is the rate of metabolism when the person
should be awake & is in complete physical and mental rest and in the normal
environments, using minimum energy just to maintain the essential life processes
(functioning of heart, lungs, nervous system and kidneys). It is measured as per
unit of body surface area (in Sq. Metres) per hour and to be taken 12 hours after
a meal.
25
DIABETES
CARREOGRAPH
become inactive. Both factors are responsible to develop diabetes mellitus.
In our country about 95% of the diabetics are suffering from diabetes mellitus.
India is considered as diabetic capital of the world observing the high number of
Diabetic patients in our country.
26
DIABETES
CARREOGRAPH
27
EXPANSION OF ABBREVIATIONS
CARREOGRAPH
WHO World Health Organization
ENT Ear, Nose and Throat
MBBS Bachelor of Medicine, Bachelor of Surgery
MD Doctor of Medicine
MS Master of Surgery
GP General Practitioner
Phy Physician
MRCP Member of Royal College of Physicians
FRCS Fellow of Royal College of Surgeons
Gynaecologist Doctor that deals with female disease
Cardiologist Doctor that deals with heart disease
Neurologist Doctor that deals with diseases of nervous system
Dermatologist Doctor that deals with skin disease
Paediatrician Doctor that deals with child disease
Ophthalmologist Doctor that deals with eye disease
Psychiatrist Doctor that deals with mental disease
RTI Respiratory Tract Infection
UTI Urinary Tract Infection
MRP Maximum Retail Price
mcg Microgram
mg Milligram
ml Millilitre
g/gm Gramme
Hb Haemoglobin
DM Doctorate of Medicine
28
EXPANSION OF ABBREVIATIONS
CARREOGRAPH
IP
HDL High Density Lipoprotein
LDL Low Density Lipoprotein
VLDL Very low density lipid
TG Triglyceride
DPCO Drug price control order
Rx Take it ( prescription writing)
o.d Once daily
b.d. or b.i.d. Twice daily
t.d.s. or t.i.d. Thrice daily
q.d. or q.i.d. Four times daily
i.m. Intramuscular
i.v. Intravenous
I.U. International Unit
CSF Cerebrospinal fluid
CNS Central Nervous System
SOS As and when required
DNA Deoxyribonucleic acid
RNA Ribonucleic acid
Analgesic Medicine that relieves pain
Antipyretic Medicine that relieves body fever
29
CARDIOVASCULAR SYSTEM
What is BLOOD ?
Blood is red and liquid connective tissue of alkaline reaction consisting of cells and
plasma.
BLOOD
CARREO GRAPH
1. ERYTHROCYTES (5 Million /mm3)
2. PLASMA PROTEINS (7 - 8%)
2. LEUCOCYTES (6 - 8 Thousand /mm3)
3. SOLUBLE SUBSTANCES (1 - 2%)
3. THROMBOCYTES (2.5 - 4 Lakhs/mm3)
What is Haemoglobin ?
Oxygen-rich Blood
Haemoglobin is a red pigment containing iron linked Oxygen-poor Blood
to a protein in RBC
Haem = iron , Globin = Protein
CARDIOVASCULAR SYSTEM
CARREOGRAPH
4) Act as Anti Histamine
What is ANAEMIA?
Deficiency of RBC and haemoglobin in the blood is called anaemia.
(Normal haemoglobin in blood is around 14.5 gm%)
What is pH?
pH is a scale used to specify how acidic or basic a water based solution is.
What is artery?
Blood vessels having three layers carrying blood away from the heart. All arteries
except pulmonary artery carry oxygenated blood.
What is vein ?
Blood vessels having three layers less in thickness than artery carrying blood
towards the heart. All veins except pulmonary veins carry deoxygenated blood.
31
CARDIOVASCULAR SYSTEM
CARREOGRAPH
From which chamber blood is circulated through out our body ?
From left ventricle through Aorta
CARDIOVASCULAR SYSTEM
CARREOGRAPH
4. Elasticity of the blood vessels.
5. Blood volume.
6. Blood viscosity.
What is BradyCardia?
Means low rate of heart beat than normal.
What is Tachycardia ?
Means increase of heart beat than normal.
CARDIOVASCULAR SYSTEM
What is Atherosclerosis ?
Hardening , narrowing of blood vessels .This is due to deposition of cholesterol and
Other substances with the eventual obstruction of blood flow.
CARREOGRAPH
3) They pour blood in the right atrium.
4) Then to right ventricle (through Tricuspid valve)
5) The blood is sent to the lungs (through pulmonary arteries) for gaseous
Exchange.
6) Then oxygenated blood is poured into left atrium (via pulmonary veins)
7) From where it comes to the left ventricle(through Bicuspid or Mitral valve)
8) From the left ventricle , the blood is supplied to different parts of the
body through Aorta
CAR REOGRAPH
Pair of Right Pair of Left
Pulmonary Vain Pulmonary Vein
Right Pulmonary
Arte
Left Pulmonary
Artery
Inferior Capillaries
Vena -
Cava
TRUNK AND LOWER LIMBS
CARREOGRAPH
ANTISEPTIC : A substance destructive to micro-organisms or
preventing sepsis.
HAEMOPOIETIC : Relating to formation of blood.
IMMUNITY : The body's ability to resist infection , afforded by the
presence of circulating antibodies and W.B.C.
OEDEMA : Presence of excessive amounts of fluid in tissues.
ARRHYTHMIA : Departure from normal regular heart rhythm.
EMBOLISM : Obstruction of blood vessel by a clot.
HYPERTENSION : Blood pressure above normal levels.
HYPOTENSION : Blood pressure below normal levels.
LEUKAEMIA : Pathological abnormality and increase in W.B.C number
INFARCTION : Area of dead tissue produced by obstruction of artery.
PALPITATION : Irregular heart beat.
STENOSIS : Narrowing of vein or artery
ANAEMIA : A reduction in the quantity of the oxygen-carrying pigment
"haemoglobin" in the blood.
ATHEROSCLEROSIS: Hardening ,narrowing of inner layer of blood vessels
due to deposition of cholesterol and loss of elasticity.
THROMBUS : Clot fixed to vessel wall produced by coagulation of blood/lipid.
HYPERSENSITIVITY`: Abnormal reaction of body tissue to certain products
( ALLERGY)
HEART ATTACK : Sudden severe chest pain following interruption of blood
supply in coronary arteries.
THALASSAEMIA : A hereditary blood disease , in which there is an abnormality
in the protein part of haemoglobin molecule affecting R.B.C.
Followed by anemia.
36
NOTE
37
RESPIRATORY SYSTEM
CARREO GRAPH
What are the Muscles & Bones involved in Respiration?
Two muscles of our body play very important role in respiration. They are Diaphragm and
Intercostal Muscles and two bones involved in respiration - Ribs and Sternum.
Major Organs of Respiration:
NOSE and NASAL CAVITY Nose is a structure made
up of cartilage with openings called nostrils which
allow the air to flow in or out. Nasal Cavities are the
spaces in bones of face which are filled with air.
EPIGLOTTIS A flap of cartilaginous structure in the
throat that keeps food from entering the
Air
respiratory tract.
LARYNX an organ serving as an air passage
conveying air to trachea and also responsible for Epiglottis
production of vocal sounds.
TRACHEA part of air passage between larynx and bronchi,
composed of smooth muscle with fixed incomplete cartilage.
Trachea bifurcates into right and left Bronchi.
LUNG a pair of organs of respiration, situated in the chest cavity on either
side of heart and enclosed by a double serous membrane called Pleura.
Inflammation of the Pleura is called Pleuritis or Pleurisy.
ALVEOLI a single alveolus is a microscopic single layer air sac covered with pulmonary
capillaries where oxygen and carbon dioxide can be readily exchanged.
What is Cough?
Cough is a protective reflex of the body, often Sudden and repetitive to clear out irritants, dust,
food particles, microbes etc from the respiratory passages. It can be voluntary or involuntary
in nature.
IMMUNITY AND VACCINE
VACCINES are suspensions of dead or attenuated but live microorganisms or products
obtained from them used as antigens when administered develop one or more types of
specific antibodies in the body. Vaccines are employed prophylactically and are of no value
during incubation period or in the active stage of disease.
IMMUNITY can be defined as the ability of the body to neutralize and eliminate the
pathogenic microorganisms and their toxic products, thus affording prevention of diseases.
38
CARREOGRAPH
DYSPNOEA : Difficulty in breathing.
RESPIRATORY SYSTEM
CARREOGRAPH
Epiglottis
Larynx
Trachea
Rib Cage
Pleural
Bronchus Membranes
NOTE
41
1) Chlamydiae 2) Fungi
3) Protozoa (Entamoeba histolytica) 4) Rickettsiae
5) Mycoplasmatales 6) Viruses
7) Bacteria
CLASSIFICATION OF BACTERIA
CARREOGRAPH
e.g Mycobacterium Tuberculosis Haemophilus influenzae
. Bacillus anthracis Neisseria gonorrhoeae
Clostridium tetani Bordetella pertusis
Staphylococcus aureus Neisseria meningitidis
AEROBES ANAEROBES
(Can live & grow in oxygen) (Can live & Grow without oxygen)
C) According to Morphology
CARRE OGRAPH
43
3) Beta Lactams ( Bactericidal) - Penicillin , end with “cillin” or start with “ceph” / “cef”.
e.g. Ampicillin, Cloxacillin, Amoxycillin , Oxacillin, Methicillin
CARREOGRAPH
Cephalosporins : -
st
1 Generation : Cefazolin, Cefadroxil, Cephalexin
nd
2 Generation : Cefaclor, Cefoxitin, Cefuroxime, Cefprozil
rd
3 Generation : Cefixime, Cefoperazone, Cefotaxime,
Ceftazidime, Ceftizoxime, Ceftriaxone
th
4 Generation : Cefepime, Cefeperome
th
5 Generation : Ceftobiprole , Ceftaroline, Ceftolozane
4) Beta Lactamase Inhibitors - i) CLAVULANIC ACID ii) SULBACTAM
PHARMACOLOGY
PHARMACOLOGY - The science of the properties of drugs in detail and particularly their
effects on the body is Pharmacology.
PLASMA HALF LIFE or t ½ - It is the time taken by the drug in the plasma to reduce to 50%
from its peak concentration at a particular dosage.
PHARMACODYNAMICS - The interaction of the drugs with cells. Simply, what drug does to the
body.
PHARMACOKINETICS - What the body does to the drug, which includes its absorption,
distribution, metabolism, and excretion.
ANTIBIOTIC - A chemical substance derived from a particular group of microorganisms that,
CARREOGRAPH
kills or inhibits the growth of other type of microorganisms. Nowadays most of the antibiotics
are manufactured either synthetically or semisynthetically. Antibiotics are used to treat
infections caused by organisms that are sensitive to them.
DRUG - A drug is any substance used for the purpose of DIAGNOSIS, PREVENTION,
RELIEF or CURE of a disease in MEN or ANIMALS.
AUC [Area Under Curve] - Plasma concentration of drug versus time.
TMAX - Time for peak plasma conc.
CMAX - The peak serum concentration of a drug.
Therapeutic Index (T.I) - is used to compare the therapeutically effective dose to the toxic
dose of a drug.
T.I = Toxic Dose / Lethal Dose
Effective Dose
Pharmacopoeia - An official book containing a selected list of established drugs with details of
their formulae, physical properties ,tests for their identity ,purity and potency .Few well known
pharmacopoeias are:I.P,B.P and U.S.P.
45
NERVOUS SYSTEM
ii) Peripheral Nervous System (PNS) consists of Nerves which are sensory and
motor nerves.
CARREO GRAPH
Nervous System means the vast network of cells specialized to carry information in
the form of nerve impulses to and from all parts of the body to bring about all bodily
activities.
What do you know about Central
Nervous System (CNS)?
Central Nervous System consists of Brain FRONTAL LOBE
PARIETAL
LOBE
and Spinal cord. Brain and Spinal cord LIMBIC
LOBE
controls and coordinates all nervous
activities of our body. Nerves originate from
the OCCIPITAL
LOBE
Brain and Spinal Cord and spreads
across the body. HYPOTHALAMUS
PITUITARY GLAND
MEDULLA OBLONGATA
Neuron is the smallest structural and SPINAL CORD CEREBELLUM
NERVOUS SYSTEM
Nerve impulses are electricity generated in the neurons of central nervous system
and it is conducted along the nerve fibres.
What is synapse?
A synapse is a junction between two or more neurons.
CARREOGRAPH
What is Neurotransmitter?
Neurotransmitters are chemical substances which are stored in the end of the neurons
and they help they carry nerve impulses from one neuron to other.
Meninges is a three- layered membrane that covers Brain and Spinal cord.
NOTE
48
URINARY SYSTEM
1. Filtration
CARREOGRAPH
2. Reabsorbtion of water and other dissolved substances with the help of ADH.
3. Excretion
4. Maintaining acid base balance
How filtration happens in kidney? Give a brief idea.
Blood is constantly purified in kidney .Blood coming to Glomerulus is filtered and
water, urea, creatinine and salts etc come to Bowmann's capsule .From there it
travels through the entire length of renal tubules and get collected to collecting duct.
In the passage, majority of water and salts are reabsorbed to blood with the help of
ADH and aldosterone respectively. The rest amount is excreted as urine.
Urethritis
Cystitis
Ureteritis
Pyelonephritis
Renal Abscess
49
URINARY SYSTEM
What is Nephron?
Nephron is the microscopic structural and functional unit of kidney. It is made up of
glomerulus, bowmann's capsule and renal tubules and collecting duct.
Structure of Nephron?
1. Bowman’s Capsule & Glomerulus
2. Renal Tubule - Proximal, Henle’s Loop, Distal,
3. Collecting Duct / Tubule
Bowman’s Capsule is surrounded by a tuft of capillary vessels, known as glomerulus.
Together, Bowman’s capsule & glomerulus constitute the Malpighian corpuscle.
CARREOGRAPH
What is diabetes mellitus? How many types of Diabetes we have in humans?
It is a metabolic disorder where there is impaired glucose metabolism in the body with
excessive thirst and hunger. Patient feels excessive urge to urinate. In severe cases,
sugar may excrete through urine. Lack of production of insulin or impaired insulin
utilization are common causes of Diabetes mellitus.
In humans, two types of Diabetes have been confirmed to exist.
1. Diabetes Mellitus- occurs as a results of lack of insulin
2. Diabetes Insipidus- Occurs as a result of lack of ADH
What is diuresis? Name one diuretic medication.
Increased production and excretion of urine is called Diuresis. Frusemide and
Torsemide are diuretics.
THE NEPHRON
Proximal Convoluted
Tubule
Bowman’s
Capsule
Glomerulus
Distal
Convoluted
Tubule
Arteriole from
Collecting renal artery
Tubule
Branch of renal
vein
Loop of Henle
50
NOTE
51
ENDOCRINE SYSTEM
CARREOGRAPH
2 Adrenal (Suprarenal) glands
Although the Hypothalamus is classified as a part of the brain and not as an
endocrine gland, it controls the Pituitary, the master gland for its secretion of different
hormones to influence the secretions of other endocrine glands. Pituitary has two
lobes - Anterior and Posterior.
Summary of the hormones secreted by the ANTERIOR PITUITARY gland and their
functions
Hormone Function
Growth hormone (GH) Regulates metabolism, promotes tissue
growth especially of bones and muscles.
Thyroid Gland stimulating
Stimulates growth and activity of thyroid
hormone (TSH)
gland and secretion of T3 and T4.
Adrenocorticotrophic hormone
Stimulates the adrenal cortex to secrete
(ACTH) glucocorticoids, mineralocorticoid, sexsteroids.
POSTERIOR PITUITARY secretes (1) Oxytocin for forceful uterine contractions for
smooth delivery. Posterior Pituitary also releases (2) Antidiuretic Hormone (ADH)
effecting reabsorption of water & selective substances from urinary tubules.
52
ENDOCRINES
CARREOGRAPH
3. Adrenal Gland (one pair) - Glucocorticoids, Mineralocorticoids,
Sexsteroids, Epinephrine,
Norepinephrine.
4. Islets of Langerhans (Endocrine pancreas) - Insulin, Glucagon
5. Ovary - Oestrogen, Progesterone.
6. Testis - Testosterone
7. Placenta (during pregnancy) - Progesterone & Oestrogen
Human Chorionic Gonadotropin (HCG)
In addition to the above, there are glands with probable endocrine functions:
a) Thymus b) Pineal body
Pituitary Gland
The master endocrine gland, a pea-sized body attached beneath the hypothalamus in the brain
that releases many hormones which in turn regulate the secretions of other endocrine Glands.
53
ENDOCRINE SYSTEM
CARREOGRAPH
54
REPRODUCTIVE SYSTEM
The male reproductive organs consists of Testes, Epididymis, Vas Deferens, Seminal
Vesicles, Prostate, Bulbo-urethral Gland, Prostatic Urethra, Penile Urethra and Penis.
The female organs include Ovaries, Fallopian Tubes, Uterus, Bartholin's Glands, Vagina.
Puberty - The onset of reproductive life is called puberty. It is the time when the gonads
(testes and ovaries) develop endocrine and gametogenic functions.
In the female, the Uterus is a thick-walled pear-shaped muscular hollow organ. It is
suspended in the pelvic cavity. The upper part is connected to the two Fallopian tubes, one
on each side and the lower part joins the vagina at the cervix-Vagina internal & vagina
external.
Two ovaries, one on each side of the uterus contain numerous follicles, within which the ova
CARREOGRAPH
develop. Ovulation is the process by which an ovum is released from a mature follicle. The
released ovum starts to travel through the Fallopian tube to the uterus, The fusion of a
spermatozoon and an ovum is know as Fertilization. In absence of sperm, when fertilization
does not take place, the endometrium breaks and the blood, mucus and uterine tissue are
eliminated through the vagina during 4 to 5 days in a cycle of 28 days is known as
Menstruation. In the age between 45 and 55, when the ovaries cease to produce an ovum,
menstruation ceases and the woman is no longer able to bear children. The stage is called
Menopause.
Fallopian Tube
1. Age of puberty
2. Graffian Follicle
(Ovarian Follicle)
3. Ovulation
4. Female Gamete (Ovum)
5. Corpus Leteum
6. Menstruation (Menarche) Ovum
Ovary Fimbria
7. Male Gamete
(Spermatozoa)
Uterus Cervix
8. Fertilization
9. Zygote
Vagina
10. Embryo
11. Placenta Sperm
FSH LH
12. Foetus
13. Gestation Period
14. Labour Oestrogen Progesteron
15. Menopause Oxytocin
Prolactin
55
AGE OF PUBERTY: It is the age when an adolescent reaches sexual maturity that is the
boy or girl is now capable of reproduction. This age usually ranges from 10 years to 14
years.
GRAAFIAN FOLLICLE: A mature ovarian follicle that ruptures to release the egg or ovum
during ovulation.
OVULATION: The release of the matured ovum from the ovary after the rupture of the
Graafian Follicle is called ovulation.
FEMALE GAMETE: A haploid cell containing 23 chromosomes produced from the Ovary is
called the female gamete or Ovum ( plural- Ova).
CARREOGRAPH
CORPUS LUTEUM: After the Graafian Follicle ruptures, in it's place a mass of yellow
coloured cells is formed. It is called Corpus Luteum which produces progesterone under the
action of Luteinzing Hormone.
MENSTRUATION: The shedding of the functional endometrial layer after every cycle of 28
days when there is no fertilization and therefore no embedding of the embryo on the wall of
the uterus.
MALE GAMETE: A haploid cell containing 23 chromosomes produced from the Testes is
called the male gamete or Spermatozoa (singular- Spermatozoon).
FERTILIZATION: The fusion or union of the male gamete with the female gamete is called
fertilization.
ZYGOTE: The first diploid cell of 46 chromosomes formed just after fertilization of ovum with
sperm is called zygote.
PLACENTA: It is a vascular organ which remains in direct contact with the uterine
endometrium and provides nourishment and oxygen to the growing foetus and also helps in
removal of waste products. The placenta also acts as a barrier in preventing certain disease
causing micro- organisms from reaching the foetus.
EMBRYO: The zygote starts multiplying and undergoes development; from 2 weeks to 8
weeks after fertilization it is called an embryo.
FOETUS: After 8 weeks of fertilization till birth, the embryo is now called the foetus.
GESTATION PERIOD: The entire period inside the female reproductive organs during which
the zygote becomes the fully matured foetus is called gestation. This is counted as 280 days
st
or 40 weeks from the 1 day of last menstrual cycle.
LABOUR: Under the influence of the hormone oxytocin there is painful contractions of the
myometrium of the uterus at the end of the gestation period to aid in the expulsion of the fully
grown foetus, this is called labour.
MENOPAUSE: The Menstrual Cycle stops after a certain age (45 to 55 years) in women. Her
reproductive age is over , this is called Menopause.
56
NOTE
57
THE SKIN
(STRUCTURE AND FUNCTIONS OF THE SKIN)
SKIN AN OVERVIEW :
Surface area of 1.2 to 2.2 square meters.
Weighs 4 to 5 kilograms.
Accounts for about 7% of total body weight in average adult.
A complex organ that protects its host from its environment, at the same time allowing
interaction with the environment.
A physical permeability barrier.
CARREOGRAPH
TYPES OF SKIN:
Two main kinds of human skin: glabrous skin (non hairy skin) and hair bearing skin.
Glabrous skin is found on the palms and soles and has lines and ridges (fingerprints).
THE SKIN
(STRUCTURE AND FUNCTIONS OF THE SKIN)
CARREOGRAPH
CELLS OF THE EPIDERMIS:
The Epidermis is a Squamous epithelium with four distinct cell types:
1) Keratinocytes-Cells of the epidermis which is filled with a protein called keratin.
2) Melanocytes-Produces dark brown to black pigment called Melanin, production
increases in presence of sunlight, it reflects skin colour.
3) Merkel cells-Sensory cells responsible for detecting touch, pain, pressure on the
skin.
4) Langerhan cells-Protective cells, responsible for protection from foreign particles
by phagocytosis.
DERMIS:
The Dermis is tough and elastic in nature and made up of fibrous tissue. It consists of
a dense network of blood and Lymph vessels, nerves, glands (sweat glands &
Sebaceous glands), hair roots.
The dermis is arranged in two major regions:
1) The Upper-Thin Papillary dermis - Contains Capillaries and nerve endings (Sensory)
& determines individual’s unique finger prints.
2) The Lower-Thick Reticular dermis - Contains sweat glands, larger blood vessels
& nerves.
HYPODERMIS OR SUBCUTIS:
The Hypodermis is a loose layer of Connective tissue with numerous blood vessels, it
connects the Epidermis and Dermis with the underlying tissue of muscles, bones and
cartilage. Almost 80% of the body fat is stored in the Hypodermis. It is responsible for
giving a cushioning effect against trauma and provides insulation and acts as a calorie
reserve. And also contains dense tracery of nerves.
59
THE SKIN
(STRUCTURE AND FUNCTIONS OF THE SKIN)
1) PROTECTION- The skin protects the body from the external environment and
from the invasion of micro-organisms.
2) SENSATION-The Merkel cells of the skin can detect and caution against
the external environment.
3) EXCRETION - The skin removes some amount of excess water and waste
materials through sweat glands.
CARREOGRAPH
4) THERMOREGULATION - The sweat glands regulate body temperature
through adjustment of the amount of sweat.
5) LUBRICATION of the Skin-The Sebaceous glands produces Sebum which forms
an oily covering on the skin causing a waterproofing effect and thus prevents the
skin from drying.
6) Subcutaneous fat provides cushioning effect against trauma.
SKIN LESIONS:
1) ABSCESS- A skin lesion characterised by collection of pus in a localised cavity.
2) DERMATITIS- Synonym Eczema, characterized by red inflamed epidermis with
itching.
3) URTICARIA- Allergic skin condition characterized by red swelled skin with wheals.
4) ACNE - A skin disease where sebaceous glands become inflamed,
characterised by oily skin.
Skin Infections-Skin infections are of different types and can be caused by Bacteria
(Leprosy), Fungi (Ringworm), Virus (Chicken pox, Herpes) and Parasites (Scabies,
Lice).
THE SKIN
CARREOGRAPH
61
THE EYE
The organ of vision is the eye which consists of the eyeball, roughly spherical ,located in the
orbit of the skull. The optic nerve enters the eyeball a little inside. Each eye is protected by
covering of two eyelids , along with hairs, eyelashes to keep dust away. The eyeball has
three coats :
Outer one (1) Fibrous Coat - with two parts a) Posterior part Sclera b) Anterior part Cornea
Middle one (2) Vascular Coat - (with large no. of blood vessels)
With three parts a) Posterior part Choroid b) Middle part Ciliary body c) Anterior part Iris
Inner one (3) Nervous coat is called Retina
With photosensitive receptors , where the visual impulses are generated. Two types of
cells are there : Rods to see in dim light and cone functioning in bright light.
CARREOGRAPH
Conjunctiva The exposed part of the eyeball is covered by a thin mucous membrane called
Conjunctiva. Its function is protection and
Lacrimal Gland Situated inside the upper atery fluid, the tears.
Aqueous Humour It is a transparent fluid loc has two
chambers anterior chamber (b erior chamber (between
iris and lens). The the
In the disease glaucoma the intra-ocul sure which is called intra-ocular
pressure.
Pupil The circular opening in the centre of the
iris ,t Lens The transparent crystalline structur
incoming light and focus into the re e
TEETH
Teeth are two types, Deciduous or Temporary teeth which are 20 in numbers and
permanent teeth which are 32 in numbers comprising upper and lower jaws.
Deciduous teeth start erupting at 6 months and complete by 24 months. On the other
hand permanent teeth start replacing temporary teeth from 6 years and complete by
24 years
CARRE
63
Scarfree Cream
Doctor,
For scarless healing of acne, prescribe Scarfree Cream.
Clindamycin in Scarfree Cream is a broad Spectrum antibiotic.
Whereas aloe allantoin reduces pain and regenerates new skin.
To keep the beauty of your patients, please prescribe Scarfree cream.
ONICO Tab
CARREOGRAPH
Doctor, Please prescribe Onico Tab, the oral fungicidal treatment for onychomycosis.
Onico is well absorbed upto 70 % and slowly eliminated, whereas longer half life makes it
effective for long term treatment.
Onico is effective in fungal nail infection, tinea versicolor and tinea captis.
Prescribe ONICO for effective fungicidal treatment.
Cute Shampoo
Doctor, to control itching and flaking by dandruff, prescribe Cute shampoo with
ketoconazole 2% & ZPTO 1%. Ketoconazole in Cute Shampoo treats dandruff, whereas
aloe extract offers antiseptic and moisturizer action.
Prescribe Cute shampoo to treat it from the Root.
Toximon
For the relief of the inflammatory and pruritic manifestations of steroid responsive dermatoses,
prescribe Toximon.
Toximon has fast action with high safety index.
Toximon is well tolerated and safe with once a day dosage convenience.
Please Prescribe Toximon for safer approach and long term treatment.
Coughtop
Infants suffer; it's an ordeal for their parents also.
Please Prescribe Orange CS drops with Phenylephrine & Chlorpheniramine Maleate.
In Cough, Cold symptoms like Coughing, runny nose and red eyes, prescribe Orange CS
drop to relieve nasal discomfort due to cold in Infants.
64
CARREOGRAPH
Heart, lungs, skin, liver, reproductive
Arjuna Terminalia Arjuna tissues, anemia, tumors, asthma,
arjuna myrobalan cardiac and circulatory problems.
CARREOGRAPH
Fever, pharyngitis, skin disorders,
Narikela Cocos Cocos nucifera alterative
nucifera
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