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Folate and fetal programming: a play in epigenomics?

Trends in Endocrinology and Metabolism, June 2013, Vol. 24, No. 6


Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

Drug Resistance Updates 15 (2012) 183– 210


FOLATE

FIGURE 14.1 Folate structures: Folic acid consists


of a p-aminobenzoic acid molecule (shown in
purple) linked at one end to a pteridine ring
(shown in yellow) and at the other end to a
molecule of glutamic acid (shown in green). Food
folates exist in various forms, containing from2 to
10 additional glutamate residues joined to the first
glutamate. The folate/folic acid structure can vary
by reduction of the pteridine moiety to form
dihydrofolate and tetrahydrofolate (THF),
elongation of the glutamate chain, and
substitution of 1-C units at the N5, N10, or both
positions. Folate coenzymes are formed by the
attachment of 1-C units including methyl (CH3),
methylene (eCH2e), methenyl (eCH¼), formyl
(eCH]O), or formimino (eCH]NH) groups to the
polyglutamyl form of the THF molecule.

Present Knowledge in Nutrition, Volume 1


FOLATE

Present Knowledge in Nutrition, Volume 1


FOLATE

Present Knowledge in Nutrition, Volume 1


FOLATE

Present Knowledge in Nutrition, Volume 1


FOLATE

Present Knowledge in Nutrition, Volume 1


Handbook of VITAMINS

ISBN-13: 978-0-8493-4022-2
The basis for folinic acid treatment in neuro-psychiatric disorders

Biochimie 126 (2016) 79e90


Tetrahydrobiopterin in energy metabolism and metabolic diseases

Pharmacological Research 157 (2020) 104827


Tetrahydrobiopterin and Its Multiple Roles in Neuropsychological Disorders

Neurochemical Research (2022) 47:1202–1211


Tetrahydrobiopterin and Its Multiple Roles in Neuropsychological Disorders

Neurochemical Research (2022) 47:1202–1211


Tetrahydrobiopterin in energy metabolism and metabolic diseases

Pharmacological Research 157 (2020) 104827


Nutriepigenetic regulation by folate–homocysteine–methionine axis: a review

Mol Cell Biochem (2014) 387:55–61


ORTOMOLECULAR
Curso Ortomolecular
VAMOS ESTUDAR?
Folic Acid Treatment for Patients With Vascular Cognitive Impairment: A Systematic Review and Meta-Analysis

International Journal of Neuropsychopharmacology (2022) 25(2): 136–143


Folic Acid Treatment for Patients With Vascular Cognitive Impairment: A Systematic Review and Meta-Analysis

International Journal of Neuropsychopharmacology (2022) 25(2): 136–143


Folic Acid Treatment for Patients With Vascular Cognitive Impairment: A Systematic Review and Meta-Analysis

International Journal of Neuropsychopharmacology (2022) 25(2): 136–143


Folic Acid Treatment for Patients With Vascular Cognitive Impairment: A Systematic Review and Meta-Analysis

International Journal of Neuropsychopharmacology (2022) 25(2): 136–143


Folic Acid Treatment for Patients With Vascular Cognitive Impairment: A Systematic Review and Meta-Analysis

International Journal of Neuropsychopharmacology (2022) 25(2): 136–143


Folic Acid as the Adjuvant Therapy for Chronic Schizophrenia: A Comprehensive Study on Glutathione Reductase

folic acid 2 mg Open Access Macedonian Journal of Medical Sciences. 2022 Mar 30; 10(T7):87-91
Folic Acid as the Adjuvant Therapy for Chronic Schizophrenia: A Comprehensive Study on Glutathione Reductase

folic acid 2 mg Open Access Macedonian Journal of Medical Sciences. 2022 Mar 30; 10(T7):87-91
Folic Acid as the Adjuvant Therapy for Chronic Schizophrenia: A Comprehensive Study on Glutathione Reductase

folic acid 2 mg Open Access Macedonian Journal of Medical Sciences. 2022 Mar 30; 10(T7):87-91
Folic Acid as the Adjuvant Therapy for Chronic Schizophrenia: A Comprehensive Study on Glutathione Reductase

folic acid 2 mg Open Access Macedonian Journal of Medical Sciences. 2022 Mar 30; 10(T7):87-91
Effects of Supplementation with Folic Acid and Its Combinations with Other Nutrients on Cognitive Impairment and
Alzheimer’s Disease:
A Narrative Review

Nutrients 2021, 13, 2966


Effects of Supplementation with Folic Acid and Its Combinations with Other Nutrients on Cognitive Impairment and
Alzheimer’s Disease: A Narrative Review

Nutrients 2021, 13, 2966


Effects of Supplementation with Folic Acid and Its Combinations with Other Nutrients on Cognitive Impairment and
Alzheimer’s Disease: A Narrative Review

Nutrients 2021, 13, 2966


Folic Acid and Autism: A Systematic Review of the Current State of Knowledge

Cells 2021, 10, 1976


Folic Acid and Autism: A Systematic Review of the Current State of Knowledge

Cells 2021, 10, 1976


Folate as adjunct therapy to SSRI/SNRI for major depressive disorder: Systematic review & meta-analysis

CeComplementary Therapies in Medicine 61 (2021) 102770lls 2021, 10, 1976


Folate as adjunct therapy to SSRI/SNRI for major depressive disorder: Systematic review & meta-analysis

CeComplementary Therapies in Medicine 61 (2021) 102770lls 2021, 10, 1976


Folate as adjunct therapy to SSRI/SNRI for major depressive disorder: Systematic review & meta-analysis

CeComplementary Therapies in Medicine 61 (2021) 102770lls 2021, 10, 1976


Folate as adjunct therapy to SSRI/SNRI for major depressive disorder: Systematic review & meta-analysis

CeComplementary Therapies in Medicine 61 (2021) 102770lls 2021, 10, 1976


Folate as adjunct therapy to SSRI/SNRI for major depressive disorder: Systematic review & meta-analysis

CeComplementary Therapies in Medicine 61 (2021) 102770lls 2021, 10, 1976


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


The potential use of folate and its derivatives in treating psychiatric disorders: A systematic review

Biomedicine & Pharmacotherapy 146 (2022) 112541


ORTOMOLECULAR - FOLATO

• DUAS coenzimas. Não confundir função. Metilação e hidroxilação.


• Neurotransmissores.
• Óxido nítrico.
• Uso em praticamente todas desordens psiquiátricas.

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