PEPTIDE BOND to

PROTEIN
SYNTHESIS
Prepared by: May Ann F. Cuenca
A polypeptide will have at least a
“sentence” worth of “letters” and even a
chain of 100 amino acids.
A PAPER CLIP
NECKLACE
 PROCEDURE
1. Take one paper clip.
2. Hook it up with another one.
3. Add another one on the end, and another
one, and another one, until you have a long
strand of paperclips.
4. Take a picture of your work and send it in
our group chat.
 Amino acids are linked together by peptide bonds.
PROTEIN SYNTHESIS
PROTEINS are

polypeptides
HOW PEPTIDES ARE
FORMED?
HOW PEPTIDES ARE FORMED?
Glycine (Gly, G) Alanine (Ala, A) C-terminusN-terminus
HOW PEPTIDES ARE FORMED?

Glyci
 ne (Gly, G) OH + H Alanine (Ala, A) H₂O
Water
DEHYDRATION SYNTHESIS REACTION
During protein synthesis, or translation, amino acids are covalently
bonded to each other through a peptide bond.

This reaction, which takes place within ribosome, is known as a

"dehydration synthesis reaction"

Dehydration: loss of water

Synthesis : to build
HOW PEPTIDES ARE FORMED?
 Glyci

ne (Gly, G)
OH + H Alanine (Ala, A) H₂O
Water
POLYPEPTIDES
H₂O H₂O H₂O
Glycine (Gly, G) Alanine (Ala, A) Glycine (Gly, G) Alanine (Ala, A)

PAPER-PEN ACTIVITY

• Choose at least 4 of the 20 amino acids and form a

 polypeptide.
• Take a picture of your work and once you’re done,
send it here in the classpoint and in our group chat.

PROTEIN SYNTHESIS
 Amino acids are linked together by
Amino Acid peptide bonds.
THE RELATIONSHIP A peptide is two or more amino acids
joined together by peptide bonds.

Peptide Bond
A polypeptide is a chain of many
amino acids.
A protein contains one or more

polypeptides
folded into three dimensional structure.

Therefore, proteins are long chains of amino acids held together

by peptide bonds.

THANK YOU
 FOR
LISTENING!