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vers.

EN 002
IRON Food supplement useful in case of sideropaenic anaemia.
contributes to the normal ZINC
20 SOLUBLE ORAL POWDER
formation of blood red cells and contributes to the normal
SINGLE-DOSE SACHETS
haemoglobin and to the normal functioning of the immune
LIPOSOME TECHNOLOGY
carriage of oxygen system
GLUTEN AND LACTOSE FREE
in the organism
SUITABLE FOR VEGETARIANS AND VEGANS

EMEFORT 1 SACHET % NRVs DOSAGE AND USE


1 sachet per day, preferably in
Iron 30 mg 214,3 the morning.
Folic acid 200 mcg 100 Lemon flavor.
Vitamin C 80 mg 100

NOT ONLY IRON Zinc 10 mg 100

NRVs: Nutritional References Values (for adults) for vitamins and mineral salts according to Reg. (UE) n.1169/2011.

FOLATE
BIBLIOGRAPHY
contributes to maternal tissue
VITAMIN C growth during pregnancy
1. Abbaspour N., Hurrell R., Kelishadi R. Review on iron
and its importance for human health. J Res Med Sci.
7. Ralli C., Ghiandai G., Imperiali P., Duranti E. Efficacia
della somministrazione di ferro liposomiale orale vs
increases iron absorption 2014 Feb; 19(2): 164–174. ferro gluconato endovena in emodialisi. Lavoro pre-
and to the normal 2. Cetin I., Berti C., Calabrese S. Role of micronutrien- sentato al 55° Congresso Nazionale Società Italiana
tes in the periconceptional period. Human repro- Nefrologia, Catania 2014.
haematopoiesis duction Update, vol.0, n.0 pp. 1-16, 2009. 8. Reig Isart F. Absorción de hierro administrado por
3. Gisbert J. P., Gomollón F., Muñoz M., Villar I., Gar- via oral. CSIC Conseil Superior d’Investigations
cía-Erce J.A. An update on iron physiology. World J Cientifiques – Barcellona. January 1999.
Gastroenterol 2009 October 7; 15(37): 4617-4626. 9. Reig Isart F. Iron absorption after oral administration

Technical sheet for physicians and pharmacists only, public distribution is forbidden.
4. http://www.allianceanemia.org/home.html of different dosage form. Efficacy of lipofer dispersi-
5. Kozubek A., Gubernator J., Przeworska E., Stasiuk ble iron absorption in rats. CSIC Conseil Superior d’In-
FOLATE, IRON and VITAMIN C M. Liposomal drug delivery, a novel approach: PLA- vestigations Cientifiques – Barcellona. January 1999.
Rosomes. Acta Biochim Pol. 2000;47(3):639-49. 10. Sharif Mohammad Shaheen, Fazle Rabbi Shakil Ah-
contribute to fatigue and weariness reduction. 6. Núñez M.T. Regulatory mechanisms of intestinal med, Md. Nazir Hossen, Maruf Ahmed, Md. Shah
iron absorption-uncovering of a fast-response me- Amran, Md. Anwar. Liposome as a carrier for ad-
chanism based on DMT1and ferroportin endocyto- vanced drug delivery. Pakistan Journal of Biologi-
sis. Biofactors. 2010 Mar-Apr;36(2):88-97. doi: cal Sciences. Year: 2006, Volume: 9, Issue: 6, Page
ZINC and VITAMIN C 10.1002/biof.84. No.: 1181-1191.
contribute to cells protection from oxidative stress

FOLATE and ZINC


play a role in cell division process (haematopoiesis)
INPHA DUEMILA Srl
Via Elettrochimica, 37 - 23900 Lecco - Italy
www.inpha2000.com
Printed on eco-friendly paper
IRON-DEFICIENCY WHEN IRON SUPPLEMENTATION LIPOSOMAL IRON Fe

AND SIDEROPAENIC ANAEMIA IS NECESSARY? Ferric pyrophosphate conveyed


within a phospholipid membrane
Iron-deficiency anaemia is caused by: • In lacking states or in increased needs • In case of malabsorption problems
• low iron-rich food intake (i.e.: red meat, • During pregnancy and breastfeeding • In anaemia due to kidney failure
legumes, fish, oily dried fruit)
• altered intestinal absorption
• In case of copious menstrual flow • In case of blood donation
IT ALLOWS
• In postmenopausal women during hormonal • In case of intense and prolonged physical
• laxative abuse replacement therapy activity
• High bioavailability compared to other iron sources
• blood loss: hemorroids, gastritis, • In vegetarian or vegan diets
copious menstrual flow, internal organs
ulcerations mcg/dl
• pregnancy and breastfeeding 3000
• neoplasia
compared to iron

Liposomal ferric pyrophosphate


• long-term therapy with antacid, 2500
+5,0 fumarate

Iron pyrophosphate

Iron sulfate
anti-inflammatory, anticoagulant drugs
and some antibiotic classes. 2000
compared to free iron
HIGHLY BIOAVAILABLE SOURCE OF IRON
1500 +3,5 pyrophosphate

Iron fumarate
1000

Control
500
+2,7 compared to iron sulfate
8% of Western women are
IRON-DEFICIENCY SYMPTOMATOLOGY iron-deficient 0
Bioavailability
• Weariness, weakness, sleepiness, insomnia
• Pallor
15% of teenagers are • Rapid absorption
• Easy fatigue in common daily tasks affected by this deficiency:
• Irritability girls on diet and those who
• Increased heart rate and shortness of breath are becoming vegetarian are AVOIDS
• Headache particularly at risk with the
• Pro-oxidant effect of free iron
• Concentration difficulties impairment of academic and
• Vertigo (especially from lying to standing position)
sport performances • Gastric side effects, diarrhea, constipation, nausea, vomit, abdominal pain
• Nail fragility, dry hair, mouth mucosa thinning along with burning sensation
and black coloration of the feces
• Sensitivity to cold
• Higher incidence of respiratory infections during winter (like the common cold)
Suitable for • Systemic toxicity
vegetarians and vegans

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