MCQs on Molecular Basis of Inheritance

1. The nucleic acid synthesis takes place in

1. 3’-5’ direction
2. 5’-3’ direction
3. Both ways
4. Any direction

2. What is the nature of the strands of the DNA duplex?

1. Anti-parallel and complementary

2. Identical and complementary
3. Anti=parallel and non-complementary
4. Dissimilar and non-complementary

3. Hershey and Chase’s experiment was based on the principle

1. Transformation
2. Translation
3. Transduction
4. Transcription

4. AUG stands for

1. Alanine
2. Methionine
3. N-formyl methionine
4. Glycine

5. The reason behind the anti-parallel strand of DNA is

1. Hydrogen bond
2. Ionic bond
3. Phosphodiester bond
4. Disulphide bond

6. In a transcription unit, the promoter is located towards

 1. 5’end of the structural gene
2. 3’end of the structural gene
3. 5’end of the template strand
4. 3’end of the coding strand

7. Genetic information is transferred from nucleus to cytoplasm through

1. RNA
2. Anticodon
3. DNA
4. Lysosomes

8. The enzyme involved in transcription

1. DNA Polymerase I
2. DNA Polymerase III
3. RNA Polymerase
4. DNA Polymerase II

9. Select the incorrectly matched pairs

1. Purines – Nitrogenous bases cytosine, thymine and uracil

2. Recombinant DNA – DNA formed by joining the DNA segments from two
different sources
3. rRNA – RNA found in ribosomes
4. ATP – The energy-carrying compound in the cell

10. The eukaryotic replication of DNA is

1. Bidirectional with many origins

2. Unidirectional with many origins
3. Bidirectional with a single origin
4. Unidirectional with a single origin

11. Spliceosomes are absent in the cells of

 1. Plants
2. Animals
3. Bacteria
4. Fungi

12. A molecule that acts as a genetic material must fulfil the following traits,
except

1. It should be structurally and chemically unstable

2. It should have the ability to generate its replica
3. It should facilitate slow changes necessary for evolution.
4. It should be able to express itself in the form of Mendelian characters.

13. What will the amount of guanine in a DNA if the total amount of adenine
and thiamine in the DNA is 45%?

1. 45%
2. 65%
3. 27.5%
4. 22.3%

14. The gene sequence that codes for proteins are

1. Exons
2. Introns
3. Intervening sequences
4. Control regions

15. The process of RNA splicing shows the dominance of

1. RNA world
2. DNA world
3. Microbial world
4. Protein world

16. In eukaryotes, RNA II facilitates transcription of

1. rRNA
2. mRNA
 3. hnRNA
4. tRNA

17. Which non-radioactive isotope was used by Messelson and Stahl in their
experiment?

1. P32
2. S35
3. N15
4. None

18. Histones are

1. Positively charged and basic amino acids

2. Positively charged and acidic proteins
3. Negatively charged and basic proteins
4. Absent in bacteria

19. In a nucleotide, the nitrogen base is joined to the sugar molecule by

a) Phosphodiester bond b) Glycosidic bond c) Hydrogen bond d) (a) &(b)
20. If a DNA contains 1000 base pairs, what would be its length?
a) 3400 Å b) 34000 Å c) 6800 d) 1000 Å
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