DRUG STUDY

Cardiovascular Drugs
Name: Conching D. Salas Ward: N/A
Age: 27 years old Date of Admission: November 23, 2022
Gender: Female Attending Physician: N/A
Address: Habitat Bool, Tagbilaran City Chief Complaints: Irregular Heart Beats
Civil Status: Married Diagnosis: Hypertension

Generic name Dosage/ Route Classification Mechanism of Action Indication Contraindication Nursing
Brand name Frequency Responsibilities

Generic Name: 50 mg/12.5 Angiotensin II It has an additive effect
actimed losartan + mg / PO / OD Antagonists / on blood pressure
hydrochlorothiazide Diuretics reduction, reducing
blood pressure to a
Brand Name: greater degree than
Hyzaar either component
alone. This effect is
thought to be a result of
the complimentary
actions of both
components. Further,
as a result of its diuretic
effect,
hydrochlorothiazide
increases plasma renin
activity, increases
aldosterone secretion,
decreases serum
It is indicated for the Hypersensitivity to - Initiate a patient
treatment of essential the active substance whose blood pressure
hypertension in or to any of the is not adequately
patients whose blood excipients. controlled with losart
pressure is not an 50 mg monotherapy
adequately controlled with HYZAAR 50/12.5
on losartan or once daily. If blood
hydrochlorothiazide pressure remainsun
alone. controlled after about 3
weeks of therapy, the
dosage may be
increased to two
tablets of HYZAAR
50/12.5 once daily or
one tablet of HYZAAR
100/25 once daily.
- Initiate a patient
potassium, and whose blood pressure
increases the levels of is not adequately
angiotensin II. controlled with losartan
Administration of 100 mg monotherapy
losartan blocks all the with HYZAAR 100/12.5
physiologically relevant (losartan 100
actions of angiotensin II mg/hydrochlorothiazide
and through inhibition 12.5 mg) once daily. If
of aldosterone could blood pressure
tend to attenuate the remains uncontrolled
potassium loss after about 3 weeks of
associated with the therapy, increase the
diuretic. dose to two tablets of
HYZAAR 50/12.5 once
daily or one tablet of
HYZAAR 100/25 once
daily.