Multimode Inlet 1.

Inlet programming
Slow solvent evaporation and
maximizes analyte transfer
Standard 11mm septa into column/detector.
Turn-top easy liner exchange No leaks at liner

2. Large volume injections

Decrease MDL by injecting more
sample.
Air plus CO2, N2
cryogenic cooling
Standard liner
dimensions

3. Thermally labile compounds

Elute analytes at lowest possible
Standard column nut temperature, minimizing breakdown and
absorption

GC Features
Agilent Restricted
Page 15 October 2014
 More inlet………

Volatile inlet

Purged pack inlet

Cool on column

GC Features
Agilent Restricted
Page 16 October 2014
GC Features

Flow
control

Electronic flow control = EPC

GC Features
Agilent Restricted
Page 17 October 2014
5th Generation Pneumatic Control
7890B GC
3rd, 4th Generation EPC
- 0.01 psi The only GC to regulate
- Diffusion bonded plate (2D)
pressure to 0.001 psi
- one cable The only EPC regulating
- three gas connectors pressure to 1/1000 psi
- “credit card” size

6890N GC
1st, 2nd Generation EPC
- 0.1 psi
- cables 5th Generation EPC
- gas lines & connectors - Metal injection molded (3D)
- large size - Digital signal pathways

5890 GC
… improved reliability and precision

GC Features
Agilent Restricted
Page 18 October 2014
EPC enables variable gas flow with time

vary the pressure with time

GC Features
Agilent Restricted
Page 19 October 2014
GC Features

Oven

Air heating
Direct heating

GC Features
Agilent Restricted
Page 20 October 2014
Column Heating

Standard Low Thermal Mass

Indirect heating with air Direct heating with wire

GC Features
Agilent Restricted
Page 21 October 2014
Approaches to Column Heating

Typical • Limitation on how fast the

column can be heated.

Heating
Air Column
element

Low Thermal Mass

Heating
Column
element

GC Features
Agilent Restricted
Page 22 October 2014
Low Thermal Mass Column Heating
Max temp : 400°C
Max ramp rate : 1,800°C/min

The heating wire is wrapped around

the column

GC Features
Agilent Restricted
Page 23 October 2014
LTM II
LTM Integrated w/ 7890 GC
- Hardware
- Firmware
- Software

GC Features
Agilent Restricted
Page 24 October 2014
LTM Provides Fast Heating

Heating speeds up to 1800oC/min

- Achievable rates depend on column

mass, configuration and column
void times

- … also including practical trade-offs

of speed vs resolution

GC Features
Agilent Restricted
Page 25 October 2014
LTM Provides Fast Cooling
Column Length
o
C 2m 5m 10 m 15 m 30 m
350->300 3 5 6 7 9
300->250 3 5 7 7 13
250->200 4 7 8 10 17
200->150 4 8 11 13 22
150->100 7 13 17 19 36
100->50 13 27 34 41 75

Type Time
350oC  50oC LTM (2m Column) 34 seconds (= 3+3+4+4+7+13)
Equilibration 3 seconds
350oC  50oC 7890 GC 3-4 minutes
Equilibration 2-3 minutes

GC Features
Agilent Restricted
Page 26 October 2014
Fast Simulated Distillation
8x Faster with LTM Compared to Conventional Method

pA

ASTM D2887 Reference Oil

2000
LTM Module : 45ºC to 350ºC at 150ºC/min
1500

1000

500

0
0.25 0.5 0.75 1 1.25 1.5 1.75 2 min
C12

pA
Analysis time reduced from
6000 16min to 2min.
C10

5000
C14
C5

C16

4000
Calibration sample C5-C44
C11

3000
C7
C8

C15

C17
C
9
C6

LTM Module : 45ºC to 350ºC at 150ºC/min

2000
C18

C20

C32

C36

C40
C24

1000
C28

0
0.25 0.5 0.75 1 1.25 1.5 1.75 2 2.25 min

GC Features
Agilent Restricted
Page 27 October 2014
Repeatable Simulated Distillation
Overlay of 10 runs

pA

900

800
LTM still give the repeatable
700
results!
600

500

400

300
Creaked gas oil, diluted 1:3 in pentane
RVM oven : 45ºC to 350ºC at 150ºC/min
200

100

0
0 0.5 1 1.5 2 2.5 min

GC Features
Agilent Restricted
Page 28 October 2014
GC Features

Flame ionization
Thermal conductivity Detector
Electron capture
Nitrogen phosphorus
Flame photometric

GC Features
Agilent Restricted
Page 29 October 2014
 When would you use these detectors

1. Flame ionization
2. Thermal conductivity
3. Electron capture
4. Nitrogen phosphorus
5. Flame photometric

GC Features
Agilent Restricted
Page 30 October 2014