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Statement for each following

1 - The coating solution is sprayed on the surface of the tab


within the pan whilst the drum is..
A- Stoped.
B- Rotated
C- offed.
2 - There is a method by which dry granules called..
A- Slugging.
B- Impaction
C- Compression
3 - Reduced segregation of formulation components during
storage &lor processing in wet granulation method leading to
reduced..
A- Intra variability
B - Inter variability
C- Intra & inter variability
4 - Granules typically have a size range between..
A- 0.2-0.8mm
B - 0.2-0.4cm
C- 0.2-0.4 mm
5 - Coloured tab are formulated to..
A- Improve toughness
B- Identify product uniquely
C- Increase tab size
6 - One example of adsorbents called…
A- Mg phosphate
B- Ca carbonate
C- kaolin bentonite
7 - Example of in soluble lubricants that is commonly used
called……
A- Polyethylene glycol (PEG).
B- Glyceryl behenate.
C-Polyoxyethylene stearates.
8 - Typically disintegration of conventional tab must occur
within…
A- 5 min.
B- 10 min.
C-15 min.
9 - Binders that commonly used in the manufacture of tab by
wet granulation are all except…
A- Acacia
B- Starch
C- Sucrose
10 - Examples of diluents for tablets are all except…
A- Anhydrous lactose
B- lactose dehydrated
C- spray- dried lactose
11 - Types of objective of mixing all except..
A- Simple physical mixture
B- Chemical change
C- Dispersion
D- Promotion of reaction
12 - The mixer uses in liquid-liquid mixing include all except..
A-Shaker mixers
B- Propeller mixers
C- Paddle mixers
D- Non of above
13 - Factors affecting on size reduction include all except..
A-Softness
B-Toughness
C-Stickness
D-Temperature
14 - Advantages for the use of granules in tab manufacture in
wet granulation method all except.
A-Prevention of segregation of powder components during the
tableting process or during storage.
B-Enhancement of the flow properties.
C-Enhancement of the compaction properties.
D-Enhancement incidence of dust production.
15 - Control of the coating process is obtained by modifying
some parameters like all except.
A-rotation rate of the drum
B-airflow rate
C- solubility of the tab material
D- concentration of sugar/polymer within the coating
solution/emulsion.
TURE OR FALSE
1 - Tablet may be formulated to contain more than one
therapeutic agents .
True / False
2 - Antacid tab formulated as effervescent tab to child & adult
have difficult in swallowing.
True / False
3 - Impaction method use for size reduction give less fines
product than compression method.
True / False
4 - Emulsion is mixture of two immiscible liquids.
True / False
5 - Roller mill is the machine used for size reduction of solids
by cutting method.
True / False
6 - In the tablet coating process the hot water is passed over
the surface of the tab to facilitate the evaporation of the
solvent in which coating material has been dissolved.
True / False
7 - No heat or solvents are required in dry granulation method.
True / False
8 - example of soluble lubricants like glyceryl behenate.

True / False

9 - Acacia binder with concentration 1-5% w/w produce hard


tablet.
True / False

10 - One example of disintegrates like MCM .

True / False
TURE OR FALSE
1 - Capsules are essay to counterfeit .
True / False
2 - hydroxy propylmethylcellulose and starch, has been
investigated as suitable replacements for gelatin .
True / False
3 - gelatin are soluble in biological fluids at room temperature
only .
True / False
4 - Hydroalcoholic solvent seal. A hydroalcoholic solution (2:1
waterlethanol) is applied to the centre of the capsule.
True / False
5 - The final hard gelatin capsules should exhibit water
content of 13-19% w/w.
True / False
6 - A wide range of capsule sizes is available that can
accommodate fill volumes between 0.20 and 0.76 ml .
True / False
7 - polyethylene glycols (PEGS) that are solid at room
temperature but will liquefy upon cooling.
True / False
8 - Initially during manufacture of thesoft gelatin capsules the
concentration of water is between 30 and 40% w/v.
True / False
9 - most imprtant step in extraction of gelatin solution by acid
process is liming process .
True / False
10 - Colorants. Most frequently hard gelatin capsules are
colored to enhance the aesthetic properties and also to act as
a means of identifying the product .

True / False
Statement for each following
1 - example Miscellaneous excipients for soft gelatin capsules
is..
a-Titanium dioxide
b-polyhydric alcohols
c-glyceryl monostearate
d-PEGS
2 - Disintegrants used for the formulation of powder fills like
a- lactose
b-maize starch
c-colloidal silicon dioxide
d-sodium lauryl sulphate
3 - use of gelatin as a capsule material is principally due to the
excellent physicochemical and biological properties of this
material, including all except.
a-Non-toxic
b-excellent mechanical properties
c- insoluble in biological fluids at room temperature
d-Excellent rheological properties at elevated temperatures
4 - Advantages of capsules all except
a-Capsules are a convenient means of formulating substances of
abuse, e.g. temazepam.
b-The stability of therapeutic agents may be improved
c-Capsules are difficult to counterfeit.
d-Capsules (generally soft gelatin capsules) may be formulated
to decrease the oral bioavailability of poorly soluble therapeutic
agents
5 - Gelatin is a mixture of proteins that is extracted from
animal collagen derived from all except.
a-milk
b-skin

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